Click here to switch to the map view.

The map label for this gene is selA [H]

Identifier: 134300030

GI number: 134300030

Start: 2388761

End: 2390188

Strand: Reverse

Name: selA [H]

Synonym: Dred_2186

Alternate gene names: 134300030

Gene position: 2390188-2388761 (Counterclockwise)

Preceding gene: 134300031

Following gene: 134300029

Centisome position: 66.24

GC content: 43.21

Gene sequence:

>1428_bases
ATGGAGCTGCAAAAGAATAAAGATTTATTAAGAGAATTACCTAAAGTGGACCAAATCATAAAGAATCCAGCTATTGATAA
GCTATTAGATACCTACCCTAGGACTTTGGTAGTAGAAGCTGTCCGCAATTCCATTGATTCAATCAGAAAAGGCATTTTAA
ATGGACAGTTTTATCAAATTGACAAAATGCAAGAAATGGTTATTCAAGGGGTAGTGGATCTGCTGGAAAAAGAAACCCGA
CCGAACCTACGAAAAGTTATTAATGCCACTGGAGTGGTATTACATACCAATCTAGGAAGGGCATTGCTTTCTAAATCTGC
CAGAAAAGCAGTAGATGCTGTCACATCTTCCTTTTGTAACCTGGAAATCAATCTTGAATCAGGGAAAAGGGGTTCCCGGT
ATGAGCCTGTGGAGGAATTAATAACCCGACTGACCGGTGCAGAGGCTGCACTGGTAGTAAATAACAATGCCTCTGCTGTT
TTACTGGCATTGGGTACTCTAGCTAAGGGAAAAGAAGTTATCGTATCTAGAGGACAGCTTGTTGAAATTGGGGGTTCCTT
CCGAATTCCCGAGGTTATGGAACAAAGTGGAGCAATATTGGTGGAAGTAGGAGCCACCAACAAAACGCATCCTTGGGATT
ACCGCAATGGAATTTCGGAGAACACTGCCCTTTTATTACATGTACATACAAGTAACTATCGCATTGTTGGTTTTACCAGA
GAAACAACGGTGGAGGAACTGGTGGCAATTGGTAAAGAAGGTAATATTCCAGTGATGTCCGACCTAGGCAGTGGTTTCCT
GGTTGAATTATCCCAATTTGGTCTCCCCAAAGAACCCAGTGTTCAGGAAACTGTGGCAGCCGGGGCAGATGTAATAACCT
TCTCTGGTGACAAATTGTTGGGAGGGCCCCAGGCAGGAATTATTGTAGGTAAAAGACACTGGATTGAAAAGATGAAAAAA
AATCCCTTAACCCGAGCAGTTAGGATCAATAAATTTACGGTGGCGGCTTTGGAAGCAACACTGCGAGAATATCTGGATGA
ACAAGGTGTTTTGAAAAATATCCCAACGCTACGCATGCTTACAGAACCAACAGAGGAAATAAGGTCTAGGGCTAGAGAGT
TAGAAAAGAAACTTAGGATGCTTCTGAAAGTAAAGGTGGACATAGAAGTCATAGGAGGAACCTCTCAGGTAGGAGGTGGT
TCCATGCCAACGGCTGAGATGGCAACCTATATACTGGCCTGTGTACCGGAAAACTTATCGGTGGATGAGCTTGCTGTAAA
TCTACGAATGTCGGAACCTGCGGTGGTGGCAAGGGTTCAAGATGGAAAATATCAGGTGGACTTGCGAACAGTTCAATTTG
AAGAAATTGATATGTTAGCAACTGTCATGGCCAAAGTTCTAAATTCCGGGGAGGTGAGCCGGCGATGA

Upstream 100 bases:

>100_bases
GAATAAAGATAAGATTTAACCCAGCAATGCTGGGTTTCTTGCTTTTTCAGTATTGGTTACCCTATAATTGAACGAAGAAA
AGTTTGTACGGGGGAATTGT

Downstream 100 bases:

>100_bases
AGCATATTATCATTGGAACCGCAGGGCACGTGGACCATGGTAAAACCTTGCTTATTAAAACATTAACAGGAATGGATACT
GACCGTTTAAAAGAAGAGAA

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MELQKNKDLLRELPKVDQIIKNPAIDKLLDTYPRTLVVEAVRNSIDSIRKGILNGQFYQIDKMQEMVIQGVVDLLEKETR
PNLRKVINATGVVLHTNLGRALLSKSARKAVDAVTSSFCNLEINLESGKRGSRYEPVEELITRLTGAEAALVVNNNASAV
LLALGTLAKGKEVIVSRGQLVEIGGSFRIPEVMEQSGAILVEVGATNKTHPWDYRNGISENTALLLHVHTSNYRIVGFTR
ETTVEELVAIGKEGNIPVMSDLGSGFLVELSQFGLPKEPSVQETVAAGADVITFSGDKLLGGPQAGIIVGKRHWIEKMKK
NPLTRAVRINKFTVAALEATLREYLDEQGVLKNIPTLRMLTEPTEEIRSRARELEKKLRMLLKVKVDIEVIGGTSQVGGG
SMPTAEMATYILACVPENLSVDELAVNLRMSEPAVVARVQDGKYQVDLRTVQFEEIDMLATVMAKVLNSGEVSRR

Sequences:

>Translated_475_residues
MELQKNKDLLRELPKVDQIIKNPAIDKLLDTYPRTLVVEAVRNSIDSIRKGILNGQFYQIDKMQEMVIQGVVDLLEKETR
PNLRKVINATGVVLHTNLGRALLSKSARKAVDAVTSSFCNLEINLESGKRGSRYEPVEELITRLTGAEAALVVNNNASAV
LLALGTLAKGKEVIVSRGQLVEIGGSFRIPEVMEQSGAILVEVGATNKTHPWDYRNGISENTALLLHVHTSNYRIVGFTR
ETTVEELVAIGKEGNIPVMSDLGSGFLVELSQFGLPKEPSVQETVAAGADVITFSGDKLLGGPQAGIIVGKRHWIEKMKK
NPLTRAVRINKFTVAALEATLREYLDEQGVLKNIPTLRMLTEPTEEIRSRARELEKKLRMLLKVKVDIEVIGGTSQVGGG
SMPTAEMATYILACVPENLSVDELAVNLRMSEPAVVARVQDGKYQVDLRTVQFEEIDMLATVMAKVLNSGEVSRR
>Mature_475_residues
MELQKNKDLLRELPKVDQIIKNPAIDKLLDTYPRTLVVEAVRNSIDSIRKGILNGQFYQIDKMQEMVIQGVVDLLEKETR
PNLRKVINATGVVLHTNLGRALLSKSARKAVDAVTSSFCNLEINLESGKRGSRYEPVEELITRLTGAEAALVVNNNASAV
LLALGTLAKGKEVIVSRGQLVEIGGSFRIPEVMEQSGAILVEVGATNKTHPWDYRNGISENTALLLHVHTSNYRIVGFTR
ETTVEELVAIGKEGNIPVMSDLGSGFLVELSQFGLPKEPSVQETVAAGADVITFSGDKLLGGPQAGIIVGKRHWIEKMKK
NPLTRAVRINKFTVAALEATLREYLDEQGVLKNIPTLRMLTEPTEEIRSRARELEKKLRMLLKVKVDIEVIGGTSQVGGG
SMPTAEMATYILACVPENLSVDELAVNLRMSEPAVVARVQDGKYQVDLRTVQFEEIDMLATVMAKVLNSGEVSRR

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=454, Percent_Identity=47.136563876652, Blast_Score=379, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 52169; Mature: 52169

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQKNKDLLRELPKVDQIIKNPAIDKLLDTYPRTLVVEAVRNSIDSIRKGILNGQFYQI
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
DKMQEMVIQGVVDLLEKETRPNLRKVINATGVVLHTNLGRALLSKSARKAVDAVTSSFCN
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEE
LEINLESGKRGSRYEPVEELITRLTGAEAALVVNNNASAVLLALGTLAKGKEVIVSRGQL
EEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHCCCCHHEECCCCE
VEIGGSFRIPEVMEQSGAILVEVGATNKTHPWDYRNGISENTALLLHVHTSNYRIVGFTR
EEECCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEECCCEEEEEEEH
ETTVEELVAIGKEGNIPVMSDLGSGFLVELSQFGLPKEPSVQETVAAGADVITFSGDKLL
HHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCCEEEECCCEEC
GGPQAGIIVGKRHWIEKMKKNPLTRAVRINKFTVAALEATLREYLDEQGVLKNIPTLRML
CCCCCCEEECHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHHCCCCHHHCCCCHHHH
TEPTEEIRSRARELEKKLRMLLKVKVDIEVIGGTSQVGGGSMPTAEMATYILACVPENLS
CCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VDELAVNLRMSEPAVVARVQDGKYQVDLRTVQFEEIDMLATVMAKVLNSGEVSRR
HHHHEEEEEECCCEEEEEEECCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELQKNKDLLRELPKVDQIIKNPAIDKLLDTYPRTLVVEAVRNSIDSIRKGILNGQFYQI
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
DKMQEMVIQGVVDLLEKETRPNLRKVINATGVVLHTNLGRALLSKSARKAVDAVTSSFCN
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHEE
LEINLESGKRGSRYEPVEELITRLTGAEAALVVNNNASAVLLALGTLAKGKEVIVSRGQL
EEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHCCCCHHEECCCCE
VEIGGSFRIPEVMEQSGAILVEVGATNKTHPWDYRNGISENTALLLHVHTSNYRIVGFTR
EEECCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEEEECCCEEEEEEEH
ETTVEELVAIGKEGNIPVMSDLGSGFLVELSQFGLPKEPSVQETVAAGADVITFSGDKLL
HHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCCEEEECCCEEC
GGPQAGIIVGKRHWIEKMKKNPLTRAVRINKFTVAALEATLREYLDEQGVLKNIPTLRML
CCCCCCEEECHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHHCCCCHHHCCCCHHHH
TEPTEEIRSRARELEKKLRMLLKVKVDIEVIGGTSQVGGGSMPTAEMATYILACVPENLS
CCCHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
VDELAVNLRMSEPAVVARVQDGKYQVDLRTVQFEEIDMLATVMAKVLNSGEVSRR
HHHHEEEEEECCCEEEEEEECCEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA