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The map label for this gene is pqqE [H]

Identifier: 134300005

GI number: 134300005

Start: 2362516

End: 2363508

Strand: Reverse

Name: pqqE [H]

Synonym: Dred_2159

Alternate gene names: 134300005

Gene position: 2363508-2362516 (Counterclockwise)

Preceding gene: 134300006

Following gene: 134300004

Centisome position: 65.51

GC content: 49.55

Gene sequence:

>993_bases
ATGATTATATCTTGGAATACAACCAACGCCTGTAACTTGTATTGTGAACACTGCTACCGGGATGCAGGTGTAAAGGCAGA
GGAAGAGCTTTCTACCGACGAAGGCAAGAGACTACTGGATCAAATTGCCGAAGTGGGTTTTAAAATCATGATTTTCAGCG
GCGGAGAACCCTTAATGAGACCAGACATTTATGAACTGGTGGCCCATGCTAGGTCTAAGGGGCTGCGCCCGGTTTTTGGT
ACAAATGGCACCCTAATTACCCCTGAAGTGGCCAAGCGGTTGAAGGAATCTGGTGCCCTTGGCATGGGCATCAGCCTAGA
CAGTGTGGACCCTGCCAAACACGATAAATTCCGGGCTCAGGAAGGATGTTGGCAGGCAGCCGTAGAAGGTATGAGGAATT
GTCGCAGGGCGGGTCTTCCCTTCCAGATTCACACCACGGTAATGGACTGGAATTACGAGGAAGTAGAGGATCTTACGGAT
TTTGCGGTACAGGAGGGGGCAGTGGCCCACCATGTATTCTTCTTGGTACCCACTGGCAGAGCTGTTAACATTGAGCAGGA
ATCCCTGCGGGCTGAACAGTATGAAAACCTATTGCATCGCATTATGGAAAAGCAAAAGCAAGTGGACATTGAGTTGAAGC
CCACCTGTGCTCCCCAATTTATGCGCATTGCCAAGCAAATGGGTGTGGATACCCGATTCCAGCGAGGGTGCTTGGCAGGT
ACTGCCTATTGTATTATTGGTCCCAAGGGTGATGTGCAGCCCTGTGCTTACTTAAACATCCCTCTGGGCAATGTAAAAGA
GATGTCCTTTGCGGATATCTGGAAAGACAATCCTGTGTTAAAGGAACTGCGGACGATGGATTATAAGGGAGGTTGCGGCA
CCTGCGGCTATAAGAAAGTTTGTGGTGGATGTCGGGCCAGAGCATATTTTTACCACGGGGACTATATGGCGGAAGAACCC
TGGTGCTTATACCACGGTCGAAAGGGGTATTAA

Upstream 100 bases:

>100_bases
TTGTTCTCGAGACACTTACCGGCTTAAAACGGGCTGGGGCAGATATGCTTATTACCTACCATGCTCCGGAGGTTGCCAAC
TGGCTGAAGGAGGGATAAGC

Downstream 100 bases:

>100_bases
ATGCAGCTGGATCATATTGATAAACACCTGCTTGATGTTGTCCAAACGGATTTTCCCATTTGTACGGAACCCTACAGGGT
GATTGGTGAAAAAATTGGTA

Product: radical SAM domain-containing protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIISWNTTNACNLYCEHCYRDAGVKAEEELSTDEGKRLLDQIAEVGFKIMIFSGGEPLMRPDIYELVAHARSKGLRPVFG
TNGTLITPEVAKRLKESGALGMGISLDSVDPAKHDKFRAQEGCWQAAVEGMRNCRRAGLPFQIHTTVMDWNYEEVEDLTD
FAVQEGAVAHHVFFLVPTGRAVNIEQESLRAEQYENLLHRIMEKQKQVDIELKPTCAPQFMRIAKQMGVDTRFQRGCLAG
TAYCIIGPKGDVQPCAYLNIPLGNVKEMSFADIWKDNPVLKELRTMDYKGGCGTCGYKKVCGGCRARAYFYHGDYMAEEP
WCLYHGRKGY

Sequences:

>Translated_330_residues
MIISWNTTNACNLYCEHCYRDAGVKAEEELSTDEGKRLLDQIAEVGFKIMIFSGGEPLMRPDIYELVAHARSKGLRPVFG
TNGTLITPEVAKRLKESGALGMGISLDSVDPAKHDKFRAQEGCWQAAVEGMRNCRRAGLPFQIHTTVMDWNYEEVEDLTD
FAVQEGAVAHHVFFLVPTGRAVNIEQESLRAEQYENLLHRIMEKQKQVDIELKPTCAPQFMRIAKQMGVDTRFQRGCLAG
TAYCIIGPKGDVQPCAYLNIPLGNVKEMSFADIWKDNPVLKELRTMDYKGGCGTCGYKKVCGGCRARAYFYHGDYMAEEP
WCLYHGRKGY
>Mature_330_residues
MIISWNTTNACNLYCEHCYRDAGVKAEEELSTDEGKRLLDQIAEVGFKIMIFSGGEPLMRPDIYELVAHARSKGLRPVFG
TNGTLITPEVAKRLKESGALGMGISLDSVDPAKHDKFRAQEGCWQAAVEGMRNCRRAGLPFQIHTTVMDWNYEEVEDLTD
FAVQEGAVAHHVFFLVPTGRAVNIEQESLRAEQYENLLHRIMEKQKQVDIELKPTCAPQFMRIAKQMGVDTRFQRGCLAG
TAYCIIGPKGDVQPCAYLNIPLGNVKEMSFADIWKDNPVLKELRTMDYKGGCGTCGYKKVCGGCRARAYFYHGDYMAEEP
WCLYHGRKGY

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI22027536, Length=175, Percent_Identity=29.1428571428571, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37144; Mature: 37144

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISWNTTNACNLYCEHCYRDAGVKAEEELSTDEGKRLLDQIAEVGFKIMIFSGGEPLMR
CEEECCCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCCC
PDIYELVAHARSKGLRPVFGTNGTLITPEVAKRLKESGALGMGISLDSVDPAKHDKFRAQ
CHHHHHHHHHHHCCCCEEECCCCCEECHHHHHHHHHCCCCEECEECCCCCCCHHHHHHHH
EGCWQAAVEGMRNCRRAGLPFQIHTTVMDWNYEEVEDLTDFAVQEGAVAHHVFFLVPTGR
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCC
AVNIEQESLRAEQYENLLHRIMEKQKQVDIELKPTCAPQFMRIAKQMGVDTRFQRGCLAG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCHHHHCCCCCC
TAYCIIGPKGDVQPCAYLNIPLGNVKEMSFADIWKDNPVLKELRTMDYKGGCGTCGYKKV
CEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHH
CGGCRARAYFYHGDYMAEEPWCLYHGRKGY
HCCHHEEEEEEECCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MIISWNTTNACNLYCEHCYRDAGVKAEEELSTDEGKRLLDQIAEVGFKIMIFSGGEPLMR
CEEECCCCCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEEEEECCCCCCC
PDIYELVAHARSKGLRPVFGTNGTLITPEVAKRLKESGALGMGISLDSVDPAKHDKFRAQ
CHHHHHHHHHHHCCCCEEECCCCCEECHHHHHHHHHCCCCEECEECCCCCCCHHHHHHHH
EGCWQAAVEGMRNCRRAGLPFQIHTTVMDWNYEEVEDLTDFAVQEGAVAHHVFFLVPTGR
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCC
AVNIEQESLRAEQYENLLHRIMEKQKQVDIELKPTCAPQFMRIAKQMGVDTRFQRGCLAG
EECCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCHHHHCCCCCC
TAYCIIGPKGDVQPCAYLNIPLGNVKEMSFADIWKDNPVLKELRTMDYKGGCGTCGYKKV
CEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHH
CGGCRARAYFYHGDYMAEEPWCLYHGRKGY
HCCHHEEEEEEECCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA