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The map label for this gene is pbpG [H]

Identifier: 134299946

GI number: 134299946

Start: 2297788

End: 2299773

Strand: Reverse

Name: pbpG [H]

Synonym: Dred_2100

Alternate gene names: 134299946

Gene position: 2299773-2297788 (Counterclockwise)

Preceding gene: 134299948

Following gene: 134299943

Centisome position: 63.74

GC content: 44.26

Gene sequence:

>1986_bases
ATGCAACGGCCAAAGCTATTTCTCCTATTGGTGAGTTTCATTATTATATTCAATATCACGTCCGGTTGTGCGGACATTGG
ACAAAGGGAACCTCCGGATGTACCAACACCTTCTAGGATAGTGGATGTCAATAATAAATTAATTACTACCATATCTCAGA
CCAATCAAATTCCAGTTGAATTGGACCAGATTGCTCCAGAAATGCAACAAGCCATTGTGGCCATTGAAGATTATCGTTTT
TATGAACATTCTGGCATTGATATAAAGGGATTGGCACGGGCGGCTCTCATAAATATACGTAACCTTCGTATAGTGGAGGG
TGGCAGTACTATTACCCAGCAATTGGCAAAGAATTTGTATTTGGGGCCTGAACGTACCCTAGGAAGAAAAATTAAGGAAT
TATACTATACAGTACAATTGGAGCGGTCTTATACCAAAGAAGAAATATTGAATATGTATCTGAACCATGTTTATTTTGGA
CAGGGAGCTTATGGTATTGAGGCTGCGGCCCAGACTTATTTTGACAAACATGCCCAGGAACTAACCTTGGGCGAAAGTGC
TTTGCTGGCGGGACTACCCAAGGCACCAAGTTATTACGCGCCCACAACAAATTTAGCAGGAGCAAAGCAGAGGCAGCAGG
TTGTCTTAAACAGAATGCTGGAGTTGGGTATGATTACACCGGAGAAAAAGAAGCAAGCCCTTGACCAAACCATAGAACCA
CAGGCCAAAACAGAGTATTTTCAACAGGCACCGTACTTTGTTGCAGAGGTGGTTAAGTATTTTAAAAATAAATATCCAAA
TGGTATGGAGTTACTGTATTCCAGCGGCTTAACCATTCAGACTACCCTGGATATGGATATGCAGCAAGCTGCTGAACGGG
CCATAACCCAGGGATTAGGGCAGGTTAATAAAGATATGGAAGGGGCCTTGATAGCCATTGACCCAAGGAATGGTTATATA
AAGGCTATGGTTGGAGGACGCAATTGGCAGAAATCTCAATACAACCGGGCATTGGCAAAATCACAGCCGGGGTCATCCTT
TAAACCATTCCTATACACCGCTGCTATTGAATCGGGATATACCGCAGCTACCACTATTTTTTGTAAGCCCATTACCTACC
CTGGGGGATATAGGCCAAAGGATTATCATGGCTATCATTATCGTCCCTTTACCCTGAAACAGGCCCTGGCCATTTCAGAT
AACGTGGTATCTGTTCAATTGGCCGACCGTTTGGGACCAGAAGTACTGGTGCGTTATGCCAAAGCAATGGGCATTGAAAG
TAAACTGGATCCTTATTTGTCTCTGGCCCTTGGGTCCGCTGAAGTATCCCCCCTAGAAATGGCAGTTGCCTTTGGCCCCC
TGGCCAATGAAGGAATTCGAACAAAACCGCTATCCATCTTAAGGGTAACCGACAGCTCAGGTAGGGTTTTGGAAGAGGCG
CACCCCCAGCGCTACAAGGTCGTTGATGAGAAAGTGGCCTATATTGTTACCGATATGTTAAAGGCTGCGGTGCAACCCGG
TGGTACTGCGGCACAAATATCCCAATTAGTCTCGAGACCAGTGGCAGGTAAGACAGGAACCACAGATGAGTCCACCAATG
CCTGGTTTGTTGGCTATTCTCCAGAGCTAGTGGCATCGGTTTATGTTGGGTACGATGATAAAAGTAAAAAGGTTGGTTTA
ACAGGCAGTGACATTGCTGCACCTATTTGGGGTAACTTTTTTGAGGAAGCATTAAAGGGCACAGAAAAAACAGATTTTAA
AAAACCCGTGGGGGTTGTTGAGGTTAATATCTGTGCCTATGATGGACTAAAGGCTTCGGTATTTTCCAGTGACACCTTAA
GTGCTTATTTTATTAAGGGGACGGAGCCTAAAATACCTTGTTTTGGAGATTTCTGGTGGAAGGAGCAAGAAGGGCTTAGC
GAGGAGATACCTGACCAAAGAGGGAAGCAGAAAAAAAGATTAAATGAGTATGAGGAGAATCAATAA

Upstream 100 bases:

>100_bases
ATAGAATATTCTAATGGCACTTTATGGTTACCTTAATTTCACATATCCGTTTTGTTAAAGGGAAACAATTAAAAAAGATT
CTAAAAATCAGGAGGAAAAA

Downstream 100 bases:

>100_bases
TAAACAACAGGTGGCAACCTGTTGTTTATTATTGTAGGGTGATATTTTATTCCAGCGAACGTTCAGCTAAATAACAATTC
TCACAATAATTTGTGTCCAT

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MQRPKLFLLLVSFIIIFNITSGCADIGQREPPDVPTPSRIVDVNNKLITTISQTNQIPVELDQIAPEMQQAIVAIEDYRF
YEHSGIDIKGLARAALINIRNLRIVEGGSTITQQLAKNLYLGPERTLGRKIKELYYTVQLERSYTKEEILNMYLNHVYFG
QGAYGIEAAAQTYFDKHAQELTLGESALLAGLPKAPSYYAPTTNLAGAKQRQQVVLNRMLELGMITPEKKKQALDQTIEP
QAKTEYFQQAPYFVAEVVKYFKNKYPNGMELLYSSGLTIQTTLDMDMQQAAERAITQGLGQVNKDMEGALIAIDPRNGYI
KAMVGGRNWQKSQYNRALAKSQPGSSFKPFLYTAAIESGYTAATTIFCKPITYPGGYRPKDYHGYHYRPFTLKQALAISD
NVVSVQLADRLGPEVLVRYAKAMGIESKLDPYLSLALGSAEVSPLEMAVAFGPLANEGIRTKPLSILRVTDSSGRVLEEA
HPQRYKVVDEKVAYIVTDMLKAAVQPGGTAAQISQLVSRPVAGKTGTTDESTNAWFVGYSPELVASVYVGYDDKSKKVGL
TGSDIAAPIWGNFFEEALKGTEKTDFKKPVGVVEVNICAYDGLKASVFSSDTLSAYFIKGTEPKIPCFGDFWWKEQEGLS
EEIPDQRGKQKKRLNEYEENQ

Sequences:

>Translated_661_residues
MQRPKLFLLLVSFIIIFNITSGCADIGQREPPDVPTPSRIVDVNNKLITTISQTNQIPVELDQIAPEMQQAIVAIEDYRF
YEHSGIDIKGLARAALINIRNLRIVEGGSTITQQLAKNLYLGPERTLGRKIKELYYTVQLERSYTKEEILNMYLNHVYFG
QGAYGIEAAAQTYFDKHAQELTLGESALLAGLPKAPSYYAPTTNLAGAKQRQQVVLNRMLELGMITPEKKKQALDQTIEP
QAKTEYFQQAPYFVAEVVKYFKNKYPNGMELLYSSGLTIQTTLDMDMQQAAERAITQGLGQVNKDMEGALIAIDPRNGYI
KAMVGGRNWQKSQYNRALAKSQPGSSFKPFLYTAAIESGYTAATTIFCKPITYPGGYRPKDYHGYHYRPFTLKQALAISD
NVVSVQLADRLGPEVLVRYAKAMGIESKLDPYLSLALGSAEVSPLEMAVAFGPLANEGIRTKPLSILRVTDSSGRVLEEA
HPQRYKVVDEKVAYIVTDMLKAAVQPGGTAAQISQLVSRPVAGKTGTTDESTNAWFVGYSPELVASVYVGYDDKSKKVGL
TGSDIAAPIWGNFFEEALKGTEKTDFKKPVGVVEVNICAYDGLKASVFSSDTLSAYFIKGTEPKIPCFGDFWWKEQEGLS
EEIPDQRGKQKKRLNEYEENQ
>Mature_661_residues
MQRPKLFLLLVSFIIIFNITSGCADIGQREPPDVPTPSRIVDVNNKLITTISQTNQIPVELDQIAPEMQQAIVAIEDYRF
YEHSGIDIKGLARAALINIRNLRIVEGGSTITQQLAKNLYLGPERTLGRKIKELYYTVQLERSYTKEEILNMYLNHVYFG
QGAYGIEAAAQTYFDKHAQELTLGESALLAGLPKAPSYYAPTTNLAGAKQRQQVVLNRMLELGMITPEKKKQALDQTIEP
QAKTEYFQQAPYFVAEVVKYFKNKYPNGMELLYSSGLTIQTTLDMDMQQAAERAITQGLGQVNKDMEGALIAIDPRNGYI
KAMVGGRNWQKSQYNRALAKSQPGSSFKPFLYTAAIESGYTAATTIFCKPITYPGGYRPKDYHGYHYRPFTLKQALAISD
NVVSVQLADRLGPEVLVRYAKAMGIESKLDPYLSLALGSAEVSPLEMAVAFGPLANEGIRTKPLSILRVTDSSGRVLEEA
HPQRYKVVDEKVAYIVTDMLKAAVQPGGTAAQISQLVSRPVAGKTGTTDESTNAWFVGYSPELVASVYVGYDDKSKKVGL
TGSDIAAPIWGNFFEEALKGTEKTDFKKPVGVVEVNICAYDGLKASVFSSDTLSAYFIKGTEPKIPCFGDFWWKEQEGLS
EEIPDQRGKQKKRLNEYEENQ

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=546, Percent_Identity=32.967032967033, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI87082258, Length=388, Percent_Identity=37.6288659793814, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788867, Length=595, Percent_Identity=27.3949579831933, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI1789601, Length=177, Percent_Identity=40.6779661016949, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 73357; Mature: 73357

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPKLFLLLVSFIIIFNITSGCADIGQREPPDVPTPSRIVDVNNKLITTISQTNQIPVE
CCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEE
LDQIAPEMQQAIVAIEDYRFYEHSGIDIKGLARAALINIRNLRIVEGGSTITQQLAKNLY
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHEEECEEEEEECCCHHHHHHHHHCC
LGPERTLGRKIKELYYTVQLERSYTKEEILNMYLNHVYFGQGAYGIEAAAQTYFDKHAQE
CCCCHHHHHHHHHHHEEEEEHHHCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
LTLGESALLAGLPKAPSYYAPTTNLAGAKQRQQVVLNRMLELGMITPEKKKQALDQTIEP
HHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
QAKTEYFQQAPYFVAEVVKYFKNKYPNGMELLYSSGLTIQTTLDMDMQQAAERAITQGLG
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
QVNKDMEGALIAIDPRNGYIKAMVGGRNWQKSQYNRALAKSQPGSSFKPFLYTAAIESGY
HHCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHCCC
TAATTIFCKPITYPGGYRPKDYHGYHYRPFTLKQALAISDNVVSVQLADRLGPEVLVRYA
CEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHH
KAMGIESKLDPYLSLALGSAEVSPLEMAVAFGPLANEGIRTKPLSILRVTDSSGRVLEEA
HHHCCCHHCCHHHEEEECCCCCCHHHHHEEECCCCCCCCCCCCEEEEEEECCCCCHHHHC
HPQRYKVVDEKVAYIVTDMLKAAVQPGGTAAQISQLVSRPVAGKTGTTDESTNAWFVGYS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
PELVASVYVGYDDKSKKVGLTGSDIAAPIWGNFFEEALKGTEKTDFKKPVGVVEVNICAY
HHEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
DGLKASVFSSDTLSAYFIKGTEPKIPCFGDFWWKEQEGLSEEIPDQRGKQKKRLNEYEEN
CCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHCCHHHHHHHHHCCC
Q
C
>Mature Secondary Structure
MQRPKLFLLLVSFIIIFNITSGCADIGQREPPDVPTPSRIVDVNNKLITTISQTNQIPVE
CCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEE
LDQIAPEMQQAIVAIEDYRFYEHSGIDIKGLARAALINIRNLRIVEGGSTITQQLAKNLY
HHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHEEECEEEEEECCCHHHHHHHHHCC
LGPERTLGRKIKELYYTVQLERSYTKEEILNMYLNHVYFGQGAYGIEAAAQTYFDKHAQE
CCCCHHHHHHHHHHHEEEEEHHHCCHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
LTLGESALLAGLPKAPSYYAPTTNLAGAKQRQQVVLNRMLELGMITPEKKKQALDQTIEP
HHCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
QAKTEYFQQAPYFVAEVVKYFKNKYPNGMELLYSSGLTIQTTLDMDMQQAAERAITQGLG
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
QVNKDMEGALIAIDPRNGYIKAMVGGRNWQKSQYNRALAKSQPGSSFKPFLYTAAIESGY
HHCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHCCC
TAATTIFCKPITYPGGYRPKDYHGYHYRPFTLKQALAISDNVVSVQLADRLGPEVLVRYA
CEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHH
KAMGIESKLDPYLSLALGSAEVSPLEMAVAFGPLANEGIRTKPLSILRVTDSSGRVLEEA
HHHCCCHHCCHHHEEEECCCCCCHHHHHEEECCCCCCCCCCCCEEEEEEECCCCCHHHHC
HPQRYKVVDEKVAYIVTDMLKAAVQPGGTAAQISQLVSRPVAGKTGTTDESTNAWFVGYS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEECC
PELVASVYVGYDDKSKKVGLTGSDIAAPIWGNFFEEALKGTEKTDFKKPVGVVEVNICAY
HHEEEEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEE
DGLKASVFSSDTLSAYFIKGTEPKIPCFGDFWWKEQEGLSEEIPDQRGKQKKRLNEYEEN
CCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCHHCCHHHHHHHHHCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]