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The map label for this gene is ackA

Identifier: 134299940

GI number: 134299940

Start: 2290150

End: 2291340

Strand: Reverse

Name: ackA

Synonym: Dred_2094

Alternate gene names: 134299940

Gene position: 2291340-2290150 (Counterclockwise)

Preceding gene: 134299941

Following gene: 134299939

Centisome position: 63.51

GC content: 42.49

Gene sequence:

>1191_bases
TTGCTAGTCCTAGTTGTTAACTGTGGTAGCTCATCTATTAAGTATAAATTAATGGATATGGAGCAAGAGTCCGTTCTTCT
TTCGGGTCTATCTGAAAGAATTGGTATCGCTGGTTCTAGAATTAAACAAGAAAATAATAAAGGTGAAGAATTGGTCCTGG
AGCAAGACCTGCCAGACCATAAGGCTGCCCTAGAGACAATTTTGAAATGCATTACCGATGCTAAATATGGTGCTATCAAA
GATACTGCAGAAATTAAAGCAGTTGGTCACCGGGTTGTGCACGGTGGAGAGAAATTTAATAAGTCTGTGGTTATCGATGC
AGAGCTTATGAAAGTATTGGAAGAGATGTCCGAATTGGCACCTCTACATAACCCGCCAAATATTATAGGTATTAAGACTT
GCCAAGAACTTATGCCCCATGCTGCACAAGTGGCCGTGTTTGATACAGCTTTCCATTCTGCTATGCCTAAACATGCTTAC
ACCTATGCTGTTCCTTACGAATACTATGAGAAGTATAAAATACGCCGTTATGGCTTCCACGGCACTTCTCATAAATTTGT
TTCCCACCGAGCAGCTGAAATTTTAGGAAAGCCCGTTGAAGATTTAAAAATTATCGTTTGCCATCTGGGCAATGGTTCCA
GTATCTCAGCTGTGGGCAATGGTGTATCCCAGGATACTTCCATGGGCTTTACCCCACTGCCAGGTCTTCCCATGGGTACT
CGTACCGGTGATATGGACCCTGCCATTGTTCCCTTCTTAATGGAGAAAGAACAATTAGGAGTTAACGAAATTGGTAATGT
TCTAAACAAAAAGAGCGGGGTGCTAGGTGTATCCGGCATTAGCAGTGACTTCCGTGATTTAGAAGATGCTGCCAGTAAAG
GTAATGAGAGAGCTGAGTTAGCCCTCAATATGTTTGCCTATGGCATTATTAAATACATTGGTGCCTATACTGCAGCCTTA
GGTGGCTTGGATGCCGTTGTATTTACTGGTGGCATTGGTGAAAATTCCAAGACTATGAGAGCCAAAGTACTGAATGGCCT
AGCTTATACCGGTTTGCAAATTGATGAAGAGAAGAACAATACCCGTGGTAAAGAAGTAATCGTCAGCAAACCTGGCGCAC
CTTTTGTGGCTATGGTTGTGCCCACCAACGAAGAATTAATGATTGCCCGTGAAACCAAAGAATTGGTTTAA

Upstream 100 bases:

>100_bases
TTGGTTTGAGAAATGGTGATACTGTTTATGCCTATAAGATTCACGGACATATTTCTCAGCTTGTAAAATAAATTAAGGGT
CTTTTAAGGAGGAGAATCCA

Downstream 100 bases:

>100_bases
TAAAAGAAATAGCCAGCTTGAGAAGTATAAAAGAACACAAAAGCCGTAAATCCTCGGGGATTACGGCTTTTGATTTTTCT
AGATAATATTAAGAAAAGTA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLVLVVNCGSSSIKYKLMDMEQESVLLSGLSERIGIAGSRIKQENNKGEELVLEQDLPDHKAALETILKCITDAKYGAIK
DTAEIKAVGHRVVHGGEKFNKSVVIDAELMKVLEEMSELAPLHNPPNIIGIKTCQELMPHAAQVAVFDTAFHSAMPKHAY
TYAVPYEYYEKYKIRRYGFHGTSHKFVSHRAAEILGKPVEDLKIIVCHLGNGSSISAVGNGVSQDTSMGFTPLPGLPMGT
RTGDMDPAIVPFLMEKEQLGVNEIGNVLNKKSGVLGVSGISSDFRDLEDAASKGNERAELALNMFAYGIIKYIGAYTAAL
GGLDAVVFTGGIGENSKTMRAKVLNGLAYTGLQIDEEKNNTRGKEVIVSKPGAPFVAMVVPTNEELMIARETKELV

Sequences:

>Translated_396_residues
MLVLVVNCGSSSIKYKLMDMEQESVLLSGLSERIGIAGSRIKQENNKGEELVLEQDLPDHKAALETILKCITDAKYGAIK
DTAEIKAVGHRVVHGGEKFNKSVVIDAELMKVLEEMSELAPLHNPPNIIGIKTCQELMPHAAQVAVFDTAFHSAMPKHAY
TYAVPYEYYEKYKIRRYGFHGTSHKFVSHRAAEILGKPVEDLKIIVCHLGNGSSISAVGNGVSQDTSMGFTPLPGLPMGT
RTGDMDPAIVPFLMEKEQLGVNEIGNVLNKKSGVLGVSGISSDFRDLEDAASKGNERAELALNMFAYGIIKYIGAYTAAL
GGLDAVVFTGGIGENSKTMRAKVLNGLAYTGLQIDEEKNNTRGKEVIVSKPGAPFVAMVVPTNEELMIARETKELV
>Mature_396_residues
MLVLVVNCGSSSIKYKLMDMEQESVLLSGLSERIGIAGSRIKQENNKGEELVLEQDLPDHKAALETILKCITDAKYGAIK
DTAEIKAVGHRVVHGGEKFNKSVVIDAELMKVLEEMSELAPLHNPPNIIGIKTCQELMPHAAQVAVFDTAFHSAMPKHAY
TYAVPYEYYEKYKIRRYGFHGTSHKFVSHRAAEILGKPVEDLKIIVCHLGNGSSISAVGNGVSQDTSMGFTPLPGLPMGT
RTGDMDPAIVPFLMEKEQLGVNEIGNVLNKKSGVLGVSGISSDFRDLEDAASKGNERAELALNMFAYGIIKYIGAYTAAL
GGLDAVVFTGGIGENSKTMRAKVLNGLAYTGLQIDEEKNNTRGKEVIVSKPGAPFVAMVVPTNEELMIARETKELV

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=45.5, Blast_Score=334, Evalue=5e-93,
Organism=Escherichia coli, GI145693184, Length=397, Percent_Identity=44.5843828715365, Blast_Score=330, Evalue=1e-91,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_DESRM (A4J6A8)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113436.1
- ProteinModelPortal:   A4J6A8
- SMR:   A4J6A8
- STRING:   A4J6A8
- GeneID:   4955638
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_2094
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   SSDFRDV
- PhylomeDB:   A4J6A8
- BioCyc:   DRED349161:DRED_2094-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 42884; Mature: 42884

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLVVNCGSSSIKYKLMDMEQESVLLSGLSERIGIAGSRIKQENNKGEELVLEQDLPDH
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHH
KAALETILKCITDAKYGAIKDTAEIKAVGHRVVHGGEKFNKSVVIDAELMKVLEEMSELA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEECHHHHHHHHHHHHHC
PLHNPPNIIGIKTCQELMPHAAQVAVFDTAFHSAMPKHAYTYAVPYEYYEKYKIRRYGFH
CCCCCCCEEEHHHHHHHCCCHHHEEHHHHHHHHCCCCCCEEEECCHHHHHHHHHEEECCC
GTSHKFVSHRAAEILGKPVEDLKIIVCHLGNGSSISAVGNGVSQDTSMGFTPLPGLPMGT
CCCHHHHHHHHHHHHCCCCHHEEEEEEECCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCC
RTGDMDPAIVPFLMEKEQLGVNEIGNVLNKKSGVLGVSGISSDFRDLEDAASKGNERAEL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCHHHH
ALNMFAYGIIKYIGAYTAALGGLDAVVFTGGIGENSKTMRAKVLNGLAYTGLQIDEEKNN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHCCEEEECCCCC
TRGKEVIVSKPGAPFVAMVVPTNEELMIARETKELV
CCCCEEEEECCCCCEEEEEECCCCCEEEEECHHHCC
>Mature Secondary Structure
MLVLVVNCGSSSIKYKLMDMEQESVLLSGLSERIGIAGSRIKQENNKGEELVLEQDLPDH
CEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHH
KAALETILKCITDAKYGAIKDTAEIKAVGHRVVHGGEKFNKSVVIDAELMKVLEEMSELA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHCCCEEEECHHHHHHHHHHHHHC
PLHNPPNIIGIKTCQELMPHAAQVAVFDTAFHSAMPKHAYTYAVPYEYYEKYKIRRYGFH
CCCCCCCEEEHHHHHHHCCCHHHEEHHHHHHHHCCCCCCEEEECCHHHHHHHHHEEECCC
GTSHKFVSHRAAEILGKPVEDLKIIVCHLGNGSSISAVGNGVSQDTSMGFTPLPGLPMGT
CCCHHHHHHHHHHHHCCCCHHEEEEEEECCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCC
RTGDMDPAIVPFLMEKEQLGVNEIGNVLNKKSGVLGVSGISSDFRDLEDAASKGNERAEL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCHHHH
ALNMFAYGIIKYIGAYTAALGGLDAVVFTGGIGENSKTMRAKVLNGLAYTGLQIDEEKNN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHCCEEEECCCCC
TRGKEVIVSKPGAPFVAMVVPTNEELMIARETKELV
CCCCEEEEECCCCCEEEEEECCCCCEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA