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The map label for this gene is fabH [H]

Identifier: 134299921

GI number: 134299921

Start: 2272401

End: 2273408

Strand: Reverse

Name: fabH [H]

Synonym: Dred_2075

Alternate gene names: 134299921

Gene position: 2273408-2272401 (Counterclockwise)

Preceding gene: 134299922

Following gene: 134299920

Centisome position: 63.01

GC content: 47.12

Gene sequence:

>1008_bases
ATGCCCAACCACCTGATTCGAGCGGGCATCCTAGGTGTGGGGAGTTATGTGCCTGAACGAATACTTACCAATAAAGAGTT
AGAAAAAATAGTGGATACCAGTGACGAATGGATAAAGTCCCGTACCGGGATAAAGGAACGTAGAATAGCCGAACCAGGAA
AATCCACGTCGGATCTGGCAACCATAGCATCCAGAAGGGCGCTGGAGCATGCCGGGATAAAGCCGGAGGAACTGGACTTA
ATTATATTAACTACTTGTTCTAAGGATATGATCATACCCGCAGGGGCCTGTCTGGTTCAACAGGAACTAGGTGCAACAAA
GGCGGGGGCCTTTGACCTAGAAGCAGGTTGTTCTGGTTTTGTATATGGTCTTAGTATTGCGACACAGTTTATTGCTACCG
GAGCCATGAAACATGTTCTTGTTATTGGTTCTGAGGTTTTGTCGAAGGTGGTAAACTGGGATGATCGGAATACTTGTGTT
TTATTTGGTGATGGTGCAGGGGCCGTTGTGGTGGGACCAGTGAGTTCTGATGAAGGAGTTTTGGCCAGCAAGTTGAGTGC
TGAGGGAGCAGGTTGGGAACACCTGTATATCCCGGCTGGTGGTTCAAAAATGCCTGCGGATCCGGTCACTGTTGAGAAAA
AGCTGCATTACATACACATGAATGGTAAAGAAGTTTTTCGCTATGCAGTACGGGTAATGGAGGAAGCGTCCTTAACCCTT
TTAAAGGCAGCAAATTTGGAACTGAGTGATATTGATCTGTTAATTCCACACCAGGCCAACATGCGGATTATTGAGCACGC
TGCTAAAAAATTACGTTTGCCAATGGATAAAGTGGCTGTGAATTTAGATCGCTATGGAAACACCTCTTCTGCTTCTATAC
CCATTGCTCTGGCCGAAGCCGTTCATTCGGGTCGTGTGAAGGCTGGAGATAACCTTGTGATGGTGGCCTTTGGGGCTGGT
TTAACCTCTGGTGGAGTTGTACTGAAGTGGAGAGACAGGGAGGGATAG

Upstream 100 bases:

>100_bases
TATTAAAAATGCCCTGCGAGTGGCAAAGGAAACTGTGGAACAGGGTCTGGTTCCAGCCATTAAAGAAAGTTTGGAAAATG
ATAAGGGGGTAGAGGAGTAA

Downstream 100 bases:

>100_bases
GTACTTGAAGATAAAAACGAAATTGTGTGATTTACTAGGGATTGAGTACCCAATTTTGCAAGGGGGTATGGCCTGGGTCT
CCACTGCTGAGCTGGCTGCT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPNHLIRAGILGVGSYVPERILTNKELEKIVDTSDEWIKSRTGIKERRIAEPGKSTSDLATIASRRALEHAGIKPEELDL
IILTTCSKDMIIPAGACLVQQELGATKAGAFDLEAGCSGFVYGLSIATQFIATGAMKHVLVIGSEVLSKVVNWDDRNTCV
LFGDGAGAVVVGPVSSDEGVLASKLSAEGAGWEHLYIPAGGSKMPADPVTVEKKLHYIHMNGKEVFRYAVRVMEEASLTL
LKAANLELSDIDLLIPHQANMRIIEHAAKKLRLPMDKVAVNLDRYGNTSSASIPIALAEAVHSGRVKAGDNLVMVAFGAG
LTSGGVVLKWRDREG

Sequences:

>Translated_335_residues
MPNHLIRAGILGVGSYVPERILTNKELEKIVDTSDEWIKSRTGIKERRIAEPGKSTSDLATIASRRALEHAGIKPEELDL
IILTTCSKDMIIPAGACLVQQELGATKAGAFDLEAGCSGFVYGLSIATQFIATGAMKHVLVIGSEVLSKVVNWDDRNTCV
LFGDGAGAVVVGPVSSDEGVLASKLSAEGAGWEHLYIPAGGSKMPADPVTVEKKLHYIHMNGKEVFRYAVRVMEEASLTL
LKAANLELSDIDLLIPHQANMRIIEHAAKKLRLPMDKVAVNLDRYGNTSSASIPIALAEAVHSGRVKAGDNLVMVAFGAG
LTSGGVVLKWRDREG
>Mature_334_residues
PNHLIRAGILGVGSYVPERILTNKELEKIVDTSDEWIKSRTGIKERRIAEPGKSTSDLATIASRRALEHAGIKPEELDLI
ILTTCSKDMIIPAGACLVQQELGATKAGAFDLEAGCSGFVYGLSIATQFIATGAMKHVLVIGSEVLSKVVNWDDRNTCVL
FGDGAGAVVVGPVSSDEGVLASKLSAEGAGWEHLYIPAGGSKMPADPVTVEKKLHYIHMNGKEVFRYAVRVMEEASLTLL
KAANLELSDIDLLIPHQANMRIIEHAAKKLRLPMDKVAVNLDRYGNTSSASIPIALAEAVHSGRVKAGDNLVMVAFGAGL
TSGGVVLKWRDREG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=45.7943925233645, Blast_Score=285, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35802; Mature: 35671

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNHLIRAGILGVGSYVPERILTNKELEKIVDTSDEWIKSRTGIKERRIAEPGKSTSDLA
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCCCHHHHH
TIASRRALEHAGIKPEELDLIILTTCSKDMIIPAGACLVQQELGATKAGAFDLEAGCSGF
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCEECCCHHHHHHHHCCCCCCCEECCCCCCHH
VYGLSIATQFIATGAMKHVLVIGSEVLSKVVNWDDRNTCVLFGDGAGAVVVGPVSSDEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCH
LASKLSAEGAGWEHLYIPAGGSKMPADPVTVEKKLHYIHMNGKEVFRYAVRVMEEASLTL
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHEEE
LKAANLELSDIDLLIPHQANMRIIEHAAKKLRLPMDKVAVNLDRYGNTSSASIPIALAEA
EEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHEEEHHHCCCCCCCCCHHHHHHH
VHSGRVKAGDNLVMVAFGAGLTSGGVVLKWRDREG
HHCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure 
PNHLIRAGILGVGSYVPERILTNKELEKIVDTSDEWIKSRTGIKERRIAEPGKSTSDLA
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCCHHHHCCCCCCCHHHHH
TIASRRALEHAGIKPEELDLIILTTCSKDMIIPAGACLVQQELGATKAGAFDLEAGCSGF
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCEECCCHHHHHHHHCCCCCCCEECCCCCCHH
VYGLSIATQFIATGAMKHVLVIGSEVLSKVVNWDDRNTCVLFGDGAGAVVVGPVSSDEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCH
LASKLSAEGAGWEHLYIPAGGSKMPADPVTVEKKLHYIHMNGKEVFRYAVRVMEEASLTL
HHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHEEE
LKAANLELSDIDLLIPHQANMRIIEHAAKKLRLPMDKVAVNLDRYGNTSSASIPIALAEA
EEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHEEEHHHCCCCCCCCCHHHHHHH
VHSGRVKAGDNLVMVAFGAGLTSGGVVLKWRDREG
HHCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]