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The map label for this gene is fabD [H]

Identifier: 134299919

GI number: 134299919

Start: 2270501

End: 2271445

Strand: Reverse

Name: fabD [H]

Synonym: Dred_2073

Alternate gene names: 134299919

Gene position: 2271445-2270501 (Counterclockwise)

Preceding gene: 134299920

Following gene: 134299918

Centisome position: 62.95

GC content: 49.74

Gene sequence:

>945_bases
TTGACTAAGGTAGCATTTGTTTTCCCGGGCCAGGGTTCCCAGTATGTGGGCATGGGCAGGGAGTTATATAATAACTTTCA
AGTAGTTCGTGAAACCATGGAAGAGGCAGACGATTCGTTAGGCTTTGGATTAACAAAATTATGCTTTGAGGGACCAGTTG
AAGAACTCAATAGCACTGTGAATACTCAGCCTGCCCTATTGGCAGTTAGTGTGGCAGCCCTGAGGGTGTTGCAACAGGAA
TGCGGCATACTTCCCTCGGTGCTGGCCGGGCACAGTCTGGGCGAATACTCTGCCCTGGTGGCCGCCGGTTCAGTCCATTT
TTCGGATGCCGTTAAGGTTGTTCGTCAGAGGGGCCTGTTTATGCAGGAGGCGGCTCCTGTTGGGTCCGGTGGAATGGCAG
CGGTTCTTGGTTTGGCCAGAGAGAAGGTAGTTGCCTGTTGCCTGGAGGCCTCGTCCCATGGGGTGGTTGAACCAGTAAAT
TTCAACTGCCCAGGTCAAGTGGTTATAGCCGGGGAACAAGAAGCATTACAGCAGGCAATGGAGCTGTGCCGTGCCGCTGG
TGCCAAAAGAGCCATTGCCCTAGCTGTCAGTGGTCCTTTCCATTCCAGTCTTATGCGCCCGGCAGGTGAAAGACTAGCCC
CAATACTGGAAGAAATAGAGATTTGTGATCCGGCAATTCCAGTTATAGCCAATGTCAGTGCTGATTATGTAAGGACAGTA
CAAGAAGTAAAACAGTCCCTGGCTAAACAGGTATCCGGTGCAGTTCTTTGGGAAGACAGCATTCAAAGGATGGCTACTGA
GGGAATTAATACCTTGGTGGAATTAGGACCAGGTAAAGTTCTCTGCGGTTTGGTTAAGAAAATTTCTAAGGAAATAACCA
CTAGCAACCTGGAAGATTTGGCAAGCTTGGAAAAAGTCCTTGCACTGTTCAAGGAGGTTGGCTAA

Upstream 100 bases:

>100_bases
TATGGTTAAAAAAATAGAACCGGCCGAAGAGATCATTCAGGAAATTATTGGTGGTGCAGAGCAAGTATTAGCGCGGTTAG
CTGGAGGTGAATTTTAGAAA

Downstream 100 bases:

>100_bases
AATGTTTCTGAATGGTAAAGTTGCTATTGTCACTGGAGCATCTCGGGGAATCGGTAAAGCCATTGCCCTGGCCCTGGCCG
GAGCCCAGGCAGATATCGTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTKVAFVFPGQGSQYVGMGRELYNNFQVVRETMEEADDSLGFGLTKLCFEGPVEELNSTVNTQPALLAVSVAALRVLQQE
CGILPSVLAGHSLGEYSALVAAGSVHFSDAVKVVRQRGLFMQEAAPVGSGGMAAVLGLAREKVVACCLEASSHGVVEPVN
FNCPGQVVIAGEQEALQQAMELCRAAGAKRAIALAVSGPFHSSLMRPAGERLAPILEEIEICDPAIPVIANVSADYVRTV
QEVKQSLAKQVSGAVLWEDSIQRMATEGINTLVELGPGKVLCGLVKKISKEITTSNLEDLASLEKVLALFKEVG

Sequences:

>Translated_314_residues
MTKVAFVFPGQGSQYVGMGRELYNNFQVVRETMEEADDSLGFGLTKLCFEGPVEELNSTVNTQPALLAVSVAALRVLQQE
CGILPSVLAGHSLGEYSALVAAGSVHFSDAVKVVRQRGLFMQEAAPVGSGGMAAVLGLAREKVVACCLEASSHGVVEPVN
FNCPGQVVIAGEQEALQQAMELCRAAGAKRAIALAVSGPFHSSLMRPAGERLAPILEEIEICDPAIPVIANVSADYVRTV
QEVKQSLAKQVSGAVLWEDSIQRMATEGINTLVELGPGKVLCGLVKKISKEITTSNLEDLASLEKVLALFKEVG
>Mature_313_residues
TKVAFVFPGQGSQYVGMGRELYNNFQVVRETMEEADDSLGFGLTKLCFEGPVEELNSTVNTQPALLAVSVAALRVLQQEC
GILPSVLAGHSLGEYSALVAAGSVHFSDAVKVVRQRGLFMQEAAPVGSGGMAAVLGLAREKVVACCLEASSHGVVEPVNF
NCPGQVVIAGEQEALQQAMELCRAAGAKRAIALAVSGPFHSSLMRPAGERLAPILEEIEICDPAIPVIANVSADYVRTVQ
EVKQSLAKQVSGAVLWEDSIQRMATEGINTLVELGPGKVLCGLVKKISKEITTSNLEDLASLEKVLALFKEVG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=321, Percent_Identity=36.7601246105919, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI27477045, Length=114, Percent_Identity=43.859649122807, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1787334, Length=309, Percent_Identity=49.1909385113269, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=31.4189189189189, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=28.4745762711864, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI212642053, Length=319, Percent_Identity=26.3322884012539, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665753, Length=317, Percent_Identity=34.0694006309148, Blast_Score=150, Evalue=9e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33180; Mature: 33049

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVAFVFPGQGSQYVGMGRELYNNFQVVRETMEEADDSLGFGLTKLCFEGPVEELNSTV
CCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHC
NTQPALLAVSVAALRVLQQECGILPSVLAGHSLGEYSALVAAGSVHFSDAVKVVRQRGLF
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCH
MQEAAPVGSGGMAAVLGLAREKVVACCLEASSHGVVEPVNFNCPGQVVIAGEQEALQQAM
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHH
ELCRAAGAKRAIALAVSGPFHSSLMRPAGERLAPILEEIEICDPAIPVIANVSADYVRTV
HHHHHCCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHH
QEVKQSLAKQVSGAVLWEDSIQRMATEGINTLVELGPGKVLCGLVKKISKEITTSNLEDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHH
ASLEKVLALFKEVG
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TKVAFVFPGQGSQYVGMGRELYNNFQVVRETMEEADDSLGFGLTKLCFEGPVEELNSTV
CEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHC
NTQPALLAVSVAALRVLQQECGILPSVLAGHSLGEYSALVAAGSVHFSDAVKVVRQRGLF
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCH
MQEAAPVGSGGMAAVLGLAREKVVACCLEASSHGVVEPVNFNCPGQVVIAGEQEALQQAM
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHH
ELCRAAGAKRAIALAVSGPFHSSLMRPAGERLAPILEEIEICDPAIPVIANVSADYVRTV
HHHHHCCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHH
QEVKQSLAKQVSGAVLWEDSIQRMATEGINTLVELGPGKVLCGLVKKISKEITTSNLEDL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHH
ASLEKVLALFKEVG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]