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The map label for this gene is nuoC [H]

Identifier: 134299890

GI number: 134299890

Start: 2244064

End: 2244507

Strand: Reverse

Name: nuoC [H]

Synonym: Dred_2044

Alternate gene names: 134299890

Gene position: 2244507-2244064 (Counterclockwise)

Preceding gene: 134299891

Following gene: 134299889

Centisome position: 62.21

GC content: 42.79

Gene sequence:

>444_bases
ATGAACGGTAAACCACTGGCAGAAATTATCCAAGAACTTACAAATAAATACCCTTCATTAGAGGTATCCGAAAAAGGACA
TTTAACAGTGCCGGTAGAGTCACTGATGTTATTTATGCGTGATTTAAAGGAAATTTACGGTTTTAATTATCTTACCAATG
TAACTGGAGCGGATTATTTGGAGTATCTTGAGGTTGTCTATAACCTTTGTATCATAGGACATCCAGAAATGCTTCATGTA
AAGACCAGGCTTGATCGAAATAACCCAGAGGTTCCCTCAATGGTGCCCATCTGGGGTGGAGCCATCTGGCAGGAAAGGGA
AGTTTTTGACTTGCTGGGCATTGTCTTTACGGACCATCCTGATTTAAGGAGAATCTTACTGGCCGATGATTGGGAAGGTC
ATCCTCTCCGCAGGGATTATCAGTGGGAGGGTGGCCGAGAATAG

Upstream 100 bases:

>100_bases
GTCTATATTCCTGGTTGTGCCCCCCGGCCCGATGCAGTTATTCATGGGTTTATGAAATTAAAAGAAAAAATTATTAATCC
TGAGGTGGTGAAACGTGGCG

Downstream 100 bases:

>100_bases
GCCCTATGAGAGGTGATACACGTTGACCATTAAAACCGAAGAATTTTTATTAAATTTAGGTCCGCAGCATCCCAGTACCC
ACGGTGTTTTTAGAATTGTT

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNGKPLAEIIQELTNKYPSLEVSEKGHLTVPVESLMLFMRDLKEIYGFNYLTNVTGADYLEYLEVVYNLCIIGHPEMLHV
KTRLDRNNPEVPSMVPIWGGAIWQEREVFDLLGIVFTDHPDLRRILLADDWEGHPLRRDYQWEGGRE

Sequences:

>Translated_147_residues
MNGKPLAEIIQELTNKYPSLEVSEKGHLTVPVESLMLFMRDLKEIYGFNYLTNVTGADYLEYLEVVYNLCIIGHPEMLHV
KTRLDRNNPEVPSMVPIWGGAIWQEREVFDLLGIVFTDHPDLRRILLADDWEGHPLRRDYQWEGGRE
>Mature_147_residues
MNGKPLAEIIQELTNKYPSLEVSEKGHLTVPVESLMLFMRDLKEIYGFNYLTNVTGADYLEYLEVVYNLCIIGHPEMLHV
KTRLDRNNPEVPSMVPIWGGAIWQEREVFDLLGIVFTDHPDLRRILLADDWEGHPLRRDYQWEGGRE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=150, Percent_Identity=34.6666666666667, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI145693162, Length=78, Percent_Identity=42.3076923076923, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789076, Length=64, Percent_Identity=45.3125, Blast_Score=59, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=42.7184466019417, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=42.7184466019417, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24656494, Length=147, Percent_Identity=34.0136054421769, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17141; Mature: 17141

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKPLAEIIQELTNKYPSLEVSEKGHLTVPVESLMLFMRDLKEIYGFNYLTNVTGADYL
CCCCCHHHHHHHHHCCCCCCEECCCCCEEECHHHHHHHHHHHHHHHCCCHHHCCCCHHHH
EYLEVVYNLCIIGHPEMLHVKTRLDRNNPEVPSMVPIWGGAIWQEREVFDLLGIVFTDHP
HHHHHHHHHHHCCCCHHEEHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DLRRILLADDWEGHPLRRDYQWEGGRE
CCEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGKPLAEIIQELTNKYPSLEVSEKGHLTVPVESLMLFMRDLKEIYGFNYLTNVTGADYL
CCCCCHHHHHHHHHCCCCCCEECCCCCEEECHHHHHHHHHHHHHHHCCCHHHCCCCHHHH
EYLEVVYNLCIIGHPEMLHVKTRLDRNNPEVPSMVPIWGGAIWQEREVFDLLGIVFTDHP
HHHHHHHHHHHCCCCHHEEHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DLRRILLADDWEGHPLRRDYQWEGGRE
CCEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA