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The map label for this gene is nuoH [H]

Identifier: 134299888

GI number: 134299888

Start: 2241872

End: 2242921

Strand: Reverse

Name: nuoH [H]

Synonym: Dred_2042

Alternate gene names: 134299888

Gene position: 2242921-2241872 (Counterclockwise)

Preceding gene: 134299889

Following gene: 134299887

Centisome position: 62.16

GC content: 42.38

Gene sequence:

>1050_bases
GTGGAGAACTTATTTGTTAATTTAGCCAGCGGGTCTCGGACCCTGCTGGGGTCCGCTGGCCTACCCGGTGCGGCAACTGA
TTTCATAGTAATGTTCTTAAAATTAGGTGCTATTCTTGTATACATCTTAGTCAGTGCTCTCTGGCTGGTGTACATGGAAA
GGAAAGTATCGGCCTATATGCAGTGTCGGATAGGTCCTAACCGGGTTGGACCCTTGGGTTTGTTACAGACCACAGCGGAT
ATCGGGAAATTAATAAGCAAAGAAATTATTATTCCTAGATGTGTAGATAAAAAGTTGTTTTTGCTGGGACCTATGTTGAT
TTTTATGCCACCCTTGGCAGTCTTTGCTGTTGCTCCCTTTGGCAAAGATATGGTGGCCATCGATTTGAACATAGGAGTTT
ACTACTTCTTGGCTGTAGCTTCTTTATCAACTGTAATTGTCTGGATGTCTGGTTGGGCCTCTAACAACAAGTACTCCTTA
ATTGGAGGTATGCGCGTAGTGGCTCAAATGGTAAGCTACGAAATGCCTTTAATTTTATCCATTGTCGGGGTCATCATTTT
AACCGGAACCTTAAACATGAGCGAAATTATCCAGGCACAGGAAGGAGTTTGGTTTATCTTTCTGCAACCCCTTGGTTTTT
TAATTTACTTAATCGCAGGAGTTGCCGAAACAAACCGGGCCCCCTTTGACTTAGTAGAAGGAGAATCGGAAATTATCTGC
GGACCCTTTACTGAATATAGTGGCATGGGTTTTGCCATGTTCTTTCTGGCTGAGTATGCCAATGTTGTGCTTGTTTCCGT
AATGGCAACCACTTTGTTTTTAGGAGGTTGGCAAGCACCCTTTGGGCTTACTTTTATTCCATCCTGGATTTGGTTTTTGT
TTAAAGTATATGTGATGATTTTTCTCTTCATGTGGTTCCGTTGGACCTATCCAAGGGTTAGGGTGGATCAGTTAATGGAA
TTTGGTTGGAAGGTACTGGTTCCTCTTTCTATTGCGAATATTTTCTTAACTGGTATTGGTAAATATCTGTATCAAACACT
AGGGTGGTGA

Upstream 100 bases:

>100_bases
ATGCTACGGGGCTGGAAGATAGCGGATGTTATTGCCATTCTTGGCAGCATTGATATCGTGTTAGGTGAAGTTGATGCTTA
GATTGTAGGAGTGAGGCAAA

Downstream 100 bases:

>100_bases
TAGCATTGCATGGCAAGGGTCTAATAAAGGGTCTGGGAGTGACGATTAAGCATTTTTTTAAACCAAAGGTAACGGTGCAA
TACCCCGAGGTGCGATTGCC

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MENLFVNLASGSRTLLGSAGLPGAATDFIVMFLKLGAILVYILVSALWLVYMERKVSAYMQCRIGPNRVGPLGLLQTTAD
IGKLISKEIIIPRCVDKKLFLLGPMLIFMPPLAVFAVAPFGKDMVAIDLNIGVYYFLAVASLSTVIVWMSGWASNNKYSL
IGGMRVVAQMVSYEMPLILSIVGVIILTGTLNMSEIIQAQEGVWFIFLQPLGFLIYLIAGVAETNRAPFDLVEGESEIIC
GPFTEYSGMGFAMFFLAEYANVVLVSVMATTLFLGGWQAPFGLTFIPSWIWFLFKVYVMIFLFMWFRWTYPRVRVDQLME
FGWKVLVPLSIANIFLTGIGKYLYQTLGW

Sequences:

>Translated_349_residues
MENLFVNLASGSRTLLGSAGLPGAATDFIVMFLKLGAILVYILVSALWLVYMERKVSAYMQCRIGPNRVGPLGLLQTTAD
IGKLISKEIIIPRCVDKKLFLLGPMLIFMPPLAVFAVAPFGKDMVAIDLNIGVYYFLAVASLSTVIVWMSGWASNNKYSL
IGGMRVVAQMVSYEMPLILSIVGVIILTGTLNMSEIIQAQEGVWFIFLQPLGFLIYLIAGVAETNRAPFDLVEGESEIIC
GPFTEYSGMGFAMFFLAEYANVVLVSVMATTLFLGGWQAPFGLTFIPSWIWFLFKVYVMIFLFMWFRWTYPRVRVDQLME
FGWKVLVPLSIANIFLTGIGKYLYQTLGW
>Mature_349_residues
MENLFVNLASGSRTLLGSAGLPGAATDFIVMFLKLGAILVYILVSALWLVYMERKVSAYMQCRIGPNRVGPLGLLQTTAD
IGKLISKEIIIPRCVDKKLFLLGPMLIFMPPLAVFAVAPFGKDMVAIDLNIGVYYFLAVASLSTVIVWMSGWASNNKYSL
IGGMRVVAQMVSYEMPLILSIVGVIILTGTLNMSEIIQAQEGVWFIFLQPLGFLIYLIAGVAETNRAPFDLVEGESEIIC
GPFTEYSGMGFAMFFLAEYANVVLVSVMATTLFLGGWQAPFGLTFIPSWIWFLFKVYVMIFLFMWFRWTYPRVRVDQLME
FGWKVLVPLSIANIFLTGIGKYLYQTLGW

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=285, Percent_Identity=39.6491228070175, Blast_Score=210, Evalue=2e-54,
Organism=Escherichia coli, GI1788618, Length=312, Percent_Identity=41.9871794871795, Blast_Score=250, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38925; Mature: 38925

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLFVNLASGSRTLLGSAGLPGAATDFIVMFLKLGAILVYILVSALWLVYMERKVSAYM
CCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCRIGPNRVGPLGLLQTTADIGKLISKEIIIPRCVDKKLFLLGPMLIFMPPLAVFAVAPF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHCCHHHHHHHHHHHHCCCC
GKDMVAIDLNIGVYYFLAVASLSTVIVWMSGWASNNKYSLIGGMRVVAQMVSYEMPLILS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHH
IVGVIILTGTLNMSEIIQAQEGVWFIFLQPLGFLIYLIAGVAETNRAPFDLVEGESEIIC
HHHHHHHHCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEE
GPFTEYSGMGFAMFFLAEYANVVLVSVMATTLFLGGWQAPFGLTFIPSWIWFLFKVYVMI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FLFMWFRWTYPRVRVDQLMEFGWKVLVPLSIANIFLTGIGKYLYQTLGW
HHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENLFVNLASGSRTLLGSAGLPGAATDFIVMFLKLGAILVYILVSALWLVYMERKVSAYM
CCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QCRIGPNRVGPLGLLQTTADIGKLISKEIIIPRCVDKKLFLLGPMLIFMPPLAVFAVAPF
HCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHCCHHHHHHHHHHHHCCCC
GKDMVAIDLNIGVYYFLAVASLSTVIVWMSGWASNNKYSLIGGMRVVAQMVSYEMPLILS
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHH
IVGVIILTGTLNMSEIIQAQEGVWFIFLQPLGFLIYLIAGVAETNRAPFDLVEGESEIIC
HHHHHHHHCCCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEE
GPFTEYSGMGFAMFFLAEYANVVLVSVMATTLFLGGWQAPFGLTFIPSWIWFLFKVYVMI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FLFMWFRWTYPRVRVDQLMEFGWKVLVPLSIANIFLTGIGKYLYQTLGW
HHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA