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The map label for this gene is hslV

Identifier: 134299828

GI number: 134299828

Start: 2175178

End: 2175708

Strand: Reverse

Name: hslV

Synonym: Dred_1981

Alternate gene names: 134299828

Gene position: 2175708-2175178 (Counterclockwise)

Preceding gene: 134299829

Following gene: 134299827

Centisome position: 60.3

GC content: 45.57

Gene sequence:

>531_bases
ATGTTTCACGCAACGACCATTGTTGCTGTAAAGAGAGGTACCAAGGTTGCCGTAGCCGGTGATGGGCAGGTTACCTTTGG
ACAAAATACGATCATGAAACATACTGCCAGAAAAGTGAGACGCTTGCATAATGGTCAAGTTTTGGCAGGTTTTGCCGGGT
CGGTGGCAGACGCCTTTACGCTATTTGAAAAGTTTGAGGGAAAATTGGAAGAGTATCATGGTAACCTAATGAGGGCTGCT
GTGGAATTGGCCAAAGCCTGGCGTACTGACAAATACCTGCGCACGCTGGAGGCCATGCTGATTGTGGCCAATCAAGAACA
TCTGTTGGTTTTGTCAGGTAACGGAGAAGTTATTGAGCCGGATGAAGGAGTAACAGCCATAGGTTCCGGCGGTCCTTATG
CATTGGCAGCTGCCAGAGCACTCACAAAACACACCAATCTTTCGCCTAAAGATATAACCTATGAGGCTCTAAATTTGGCC
GCAGATATTTGTGTCTACACTAATAAAAATATTGTTGTTGAGGAAATTTAA

Upstream 100 bases:

>100_bases
ACAACTCAGATCTACACCCACGTAACAAAGAAAAAAATTAAGCGAGTTTATAAAATGAGCCACCCAAGGGCGTAGCTTTG
GAAAAGAGGAAGGGATGCTG

Downstream 100 bases:

>100_bases
TTTAGGTATCAAAGGAGTGGAGCCAATGGAAGCCCTGACGCCACGACAAACCGTAAGAGAGCTTGATAAATATATAGTGG
GCCAAGAAAAAGCCAAAAAA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFTLFEKFEGKLEEYHGNLMRAA
VELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEPDEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLA
ADICVYTNKNIVVEEI

Sequences:

>Translated_176_residues
MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFTLFEKFEGKLEEYHGNLMRAA
VELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEPDEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLA
ADICVYTNKNIVVEEI
>Mature_176_residues
MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFTLFEKFEGKLEEYHGNLMRAA
VELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEPDEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLA
ADICVYTNKNIVVEEI

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=172, Percent_Identity=58.1395348837209, Blast_Score=204, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_DESRM (A4J5Z6)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113324.1
- ProteinModelPortal:   A4J5Z6
- SMR:   A4J5Z6
- STRING:   A4J5Z6
- MEROPS:   T01.007
- GeneID:   4958112
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_1981
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   A4J5Z6
- ProtClustDB:   PRK05456
- BioCyc:   DRED349161:DRED_1981-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19067; Mature: 19067

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: ACT_SITE 5-5

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFT
CCCCEEEEEEECCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
LFEKFEGKLEEYHGNLMRAAVELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEECCCEEEEEECCCCEECC
DEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLAADICVYTNKNIVVEEI
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEEECCEEEEEEC
>Mature Secondary Structure
MFHATTIVAVKRGTKVAVAGDGQVTFGQNTIMKHTARKVRRLHNGQVLAGFAGSVADAFT
CCCCEEEEEEECCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
LFEKFEGKLEEYHGNLMRAAVELAKAWRTDKYLRTLEAMLIVANQEHLLVLSGNGEVIEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEECCCEEEEEECCCCEECC
DEGVTAIGSGGPYALAAARALTKHTNLSPKDITYEALNLAADICVYTNKNIVVEEI
CCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA