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The map label for this gene is rnjA [H]

Identifier: 134299786

GI number: 134299786

Start: 2128626

End: 2130290

Strand: Reverse

Name: rnjA [H]

Synonym: Dred_1938

Alternate gene names: 134299786

Gene position: 2130290-2128626 (Counterclockwise)

Preceding gene: 134299787

Following gene: 134299785

Centisome position: 59.04

GC content: 41.74

Gene sequence:

>1665_bases
TTGGCTAAAGAACCAAAATTAGCTGTAATTCCTTTGGGGGGATTAGGCGAGATCGGTAAAAATATGACTGCGGTGAGATT
TGGGGAAAATATTGTACTTATTGACTGTGGTTTAATGTTTCCAGAAGAGGAAATGCTGGGTATAGATATTGTAATCCCGG
ATATTACTTACCTATTGGAGCATAAGGAACAGGTTTTGGGTATTTTGCTTACACATGGTCACGAGGACCACATAGGTGCG
CTACCATATGTTTTACGACAAATCAATGTTCCTGTATATGGGTCTAAGCTGGCCCTAGGGCTAGTACAAGGAAAATTAAA
GGAACATAATTTGTTGGATCAGGTGAAATTGCATACGGTAAAACCAAGAGATACCATTCATATAGGGCCTTTCAGGATTG
AATTTATCAGAGTGTCTCATAGTATACCGGATGCAATGGCCATTGCTATTCATACACCTGTGGGGACATTGTTGCATACA
GGAGATTTTAAAATTGACCAAACACCGGTAGATGGCGAGGTCATTGATCTTCCAAGATTTGCAGCTCTGGGAGAAAAGGG
TGTATTAGTAATGATGTCGGATAGTACCAATGTTGAGCGGCCGGGCTATACCATGTCTGAGAGGGTGGTTGGTAATACCT
TTGACGAAACCTTCAGGCATGCCCAGGAAAGAATCATTATTGCAACCTTTGCATCCAACGTCCACCGACTTCAGCAGGCA
ATTTCAGTTGCCCATAAGTATGACCGTCATGTGGCAGTAGTGGGACGAAGTATGGTAAATGTCATGCAAGTAGCCAGTGA
ATTGGGATACATTCATATACCGGAGGGTACTTTAATCGAATTAGATGAAGCCGCTAGACTGCCCAAAAATAAGGTTGTCC
TTATTACCACAGGCAGTCAAGGTGAACCTATGTCTGCATTAACCCGAATTGCTATGAATGACCATCGGCAAGTTGATATT
ATGCCGGGAGATACTGTCATCATCTCTGCTACCCCGATACCCGGCAATGAGAAATTAGTTGCTCGGATTATTGATCAACT
TTTTAAGTTGGGTGCTAAGGTAATTTATGAAGCTGTTTCCGGGATTCATGTTTCTGGTCACCCCAGTCAAGAAGAATTAA
AGTTAATGCTTAATTTAGTTCGCCCTAAATTCTTTATACCTGTTCATGGAGAATATAGAATGCTGAAGAAGCATGCGGAG
TTGGCCCGTGAACTTGGAATCCCTGGAGAAAATATTTTTGTGGGCGAAAATGGCCAGGTCTTTGAGTTTTCCCGTAGGTA
TGGCAGAATGGCAGGAAGAGTGACTTCGGGAAAAATTCTTGTGGACGGGCTAGGCGTTGGGGATGTTGGAAATATTGTTT
TGCGAGATAGAAAGCAATTATCGCAGGATGGTATTTTAATCGTGGTTGTAACCATGGATAAACAAAACAATAAGGTTCTA
GCAGGACCTGACATTGTTTCGAGGGGATTTGTCTATGTTCGCGAATCGGAAATTCTGATGGAAGAAGCAAAAAATAAGGT
TAAACTAGCCTTAGATAAATGTTGTACCCGTGGAATTTCGGAATGGGCAGCAATTAAGTCTCAAGTTAGAGATGACTTAG
GCAAGTTTTTATACGAAAGAACTAGGAGAAGGCCAATGATCTTACCGATCATCATGGAAGTATAA

Upstream 100 bases:

>100_bases
AAATCACATATTTCCCCGCCTTCTCCTAGTTTCTCACCGTAAAATTACTTTATTTGTAGCAATTTTAATTGACACTAGAT
ATATTTTAGGAGGTGCGGTT

Downstream 100 bases:

>100_bases
GGTTAAAACCCCTGTCCTACATCAAAAGGACAGGGGTTTTTTCTATGGTATATTGGAAAGTATAACAGTCCCGATATGCT
TAAGGTAACTGAGCCTTAGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MAKEPKLAVIPLGGLGEIGKNMTAVRFGENIVLIDCGLMFPEEEMLGIDIVIPDITYLLEHKEQVLGILLTHGHEDHIGA
LPYVLRQINVPVYGSKLALGLVQGKLKEHNLLDQVKLHTVKPRDTIHIGPFRIEFIRVSHSIPDAMAIAIHTPVGTLLHT
GDFKIDQTPVDGEVIDLPRFAALGEKGVLVMMSDSTNVERPGYTMSERVVGNTFDETFRHAQERIIIATFASNVHRLQQA
ISVAHKYDRHVAVVGRSMVNVMQVASELGYIHIPEGTLIELDEAARLPKNKVVLITTGSQGEPMSALTRIAMNDHRQVDI
MPGDTVIISATPIPGNEKLVARIIDQLFKLGAKVIYEAVSGIHVSGHPSQEELKLMLNLVRPKFFIPVHGEYRMLKKHAE
LARELGIPGENIFVGENGQVFEFSRRYGRMAGRVTSGKILVDGLGVGDVGNIVLRDRKQLSQDGILIVVVTMDKQNNKVL
AGPDIVSRGFVYVRESEILMEEAKNKVKLALDKCCTRGISEWAAIKSQVRDDLGKFLYERTRRRPMILPIIMEV

Sequences:

>Translated_554_residues
MAKEPKLAVIPLGGLGEIGKNMTAVRFGENIVLIDCGLMFPEEEMLGIDIVIPDITYLLEHKEQVLGILLTHGHEDHIGA
LPYVLRQINVPVYGSKLALGLVQGKLKEHNLLDQVKLHTVKPRDTIHIGPFRIEFIRVSHSIPDAMAIAIHTPVGTLLHT
GDFKIDQTPVDGEVIDLPRFAALGEKGVLVMMSDSTNVERPGYTMSERVVGNTFDETFRHAQERIIIATFASNVHRLQQA
ISVAHKYDRHVAVVGRSMVNVMQVASELGYIHIPEGTLIELDEAARLPKNKVVLITTGSQGEPMSALTRIAMNDHRQVDI
MPGDTVIISATPIPGNEKLVARIIDQLFKLGAKVIYEAVSGIHVSGHPSQEELKLMLNLVRPKFFIPVHGEYRMLKKHAE
LARELGIPGENIFVGENGQVFEFSRRYGRMAGRVTSGKILVDGLGVGDVGNIVLRDRKQLSQDGILIVVVTMDKQNNKVL
AGPDIVSRGFVYVRESEILMEEAKNKVKLALDKCCTRGISEWAAIKSQVRDDLGKFLYERTRRRPMILPIIMEV
>Mature_553_residues
AKEPKLAVIPLGGLGEIGKNMTAVRFGENIVLIDCGLMFPEEEMLGIDIVIPDITYLLEHKEQVLGILLTHGHEDHIGAL
PYVLRQINVPVYGSKLALGLVQGKLKEHNLLDQVKLHTVKPRDTIHIGPFRIEFIRVSHSIPDAMAIAIHTPVGTLLHTG
DFKIDQTPVDGEVIDLPRFAALGEKGVLVMMSDSTNVERPGYTMSERVVGNTFDETFRHAQERIIIATFASNVHRLQQAI
SVAHKYDRHVAVVGRSMVNVMQVASELGYIHIPEGTLIELDEAARLPKNKVVLITTGSQGEPMSALTRIAMNDHRQVDIM
PGDTVIISATPIPGNEKLVARIIDQLFKLGAKVIYEAVSGIHVSGHPSQEELKLMLNLVRPKFFIPVHGEYRMLKKHAEL
ARELGIPGENIFVGENGQVFEFSRRYGRMAGRVTSGKILVDGLGVGDVGNIVLRDRKQLSQDGILIVVVTMDKQNNKVLA
GPDIVSRGFVYVRESEILMEEAKNKVKLALDKCCTRGISEWAAIKSQVRDDLGKFLYERTRRRPMILPIIMEV

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 61453; Mature: 61322

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEPKLAVIPLGGLGEIGKNMTAVRFGENIVLIDCGLMFPEEEMLGIDIVIPDITYLLE
CCCCCCEEEEECCCCHHHCCCCEEEEECCEEEEEEECCCCCCHHHEEEEEECCHHHHHHH
HKEQVLGILLTHGHEDHIGALPYVLRQINVPVYGSKLALGLVQGKLKEHNLLDQVKLHTV
HHHHHHEEHEECCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCHHHHEEEEE
KPRDTIHIGPFRIEFIRVSHSIPDAMAIAIHTPVGTLLHTGDFKIDQTPVDGEVIDLPRF
CCCCEEEECCEEEEEEEEECCCCCEEEEEEECCCCCEEECCCCEECCCCCCCCEECCCHH
AALGEKGVLVMMSDSTNVERPGYTMSERVVGNTFDETFRHAQERIIIATFASNVHRLQQA
HHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHEEEEEEHHHHHHHHHHH
ISVAHKYDRHVAVVGRSMVNVMQVASELGYIHIPEGTLIELDEAARLPKNKVVLITTGSQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEHHHHCCCCCCEEEEEECCC
GEPMSALTRIAMNDHRQVDIMPGDTVIISATPIPGNEKLVARIIDQLFKLGAKVIYEAVS
CCCHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIHVSGHPSQEELKLMLNLVRPKFFIPVHGEYRMLKKHAELARELGIPGENIFVGENGQV
CCEECCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCE
FEFSRRYGRMAGRVTSGKILVDGLGVGDVGNIVLRDRKQLSQDGILIVVVTMDKQNNKVL
EHHHHHHHHHHCCEECCEEEEEECCCCCCCHHEECCHHHHCCCCEEEEEEEECCCCCEEE
AGPDIVSRGFVYVRESEILMEEAKNKVKLALDKCCTRGISEWAAIKSQVRDDLGKFLYER
ECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
TRRRPMILPIIMEV
HCCCCEEEEEEECC
>Mature Secondary Structure 
AKEPKLAVIPLGGLGEIGKNMTAVRFGENIVLIDCGLMFPEEEMLGIDIVIPDITYLLE
CCCCCEEEEECCCCHHHCCCCEEEEECCEEEEEEECCCCCCHHHEEEEEECCHHHHHHH
HKEQVLGILLTHGHEDHIGALPYVLRQINVPVYGSKLALGLVQGKLKEHNLLDQVKLHTV
HHHHHHEEHEECCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHHCCCHHHHEEEEE
KPRDTIHIGPFRIEFIRVSHSIPDAMAIAIHTPVGTLLHTGDFKIDQTPVDGEVIDLPRF
CCCCEEEECCEEEEEEEEECCCCCEEEEEEECCCCCEEECCCCEECCCCCCCCEECCCHH
AALGEKGVLVMMSDSTNVERPGYTMSERVVGNTFDETFRHAQERIIIATFASNVHRLQQA
HHCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHEEEEEEHHHHHHHHHHH
ISVAHKYDRHVAVVGRSMVNVMQVASELGYIHIPEGTLIELDEAARLPKNKVVLITTGSQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEHHHHCCCCCCEEEEEECCC
GEPMSALTRIAMNDHRQVDIMPGDTVIISATPIPGNEKLVARIIDQLFKLGAKVIYEAVS
CCCHHHHHHHHCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIHVSGHPSQEELKLMLNLVRPKFFIPVHGEYRMLKKHAELARELGIPGENIFVGENGQV
CCEECCCCCHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCE
FEFSRRYGRMAGRVTSGKILVDGLGVGDVGNIVLRDRKQLSQDGILIVVVTMDKQNNKVL
EHHHHHHHHHHCCEECCEEEEEECCCCCCCHHEECCHHHHCCCCEEEEEEEECCCCCEEE
AGPDIVSRGFVYVRESEILMEEAKNKVKLALDKCCTRGISEWAAIKSQVRDDLGKFLYER
ECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
TRRRPMILPIIMEV
HCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]