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The map label for this gene is 134299765

Identifier: 134299765

GI number: 134299765

Start: 2104173

End: 2105114

Strand: Reverse

Name: 134299765

Synonym: Dred_1915

Alternate gene names: NA

Gene position: 2105114-2104173 (Counterclockwise)

Preceding gene: 134299766

Following gene: 134299764

Centisome position: 58.34

GC content: 41.51

Gene sequence:

>942_bases
ATGCTGATTGTAGATGCCCATTGTGACACCTTGACTGTCCTCACCCCACAAGGAAGAGATTTAGGAACTCTTTCCCAACG
GGGTCACATAGATATACCTAGGTTATATAGAGGTGGTATAAATGTTCAGTTTTTCGCCATTTTTATTGGACCTGATAATT
ACCATGACCCAGCGCAATACACGAAGGAAATTCTAAAGTTGTTTAATAAAGAAATCCAAAGGAATGCGTCTTCTTTATTG
CATGCCCGCAATTACGCTGATATTGTACATGCTTATGATTCAAAAAAGATTTGTGCTGTCCTTACCATTGAGGGTGGAGA
AGCATTAAAGGGGAAAATTGAGCAACTGGAAAGCTACTATACACAGGGGATTAGGGGCCTGACTTTAACCTGGAACGGTA
GGAATGAATTAGGGGATGGAGTGGGTTTAGGCCCCGAGGCATCAGGATTAACCGTTTTTGGACGACAGGTGATTCAAAAA
ATGGTAGAATTGGGTATGATGATTGATGTATCCCATTTATCTGAAGCAGGGTTTTGGGATGTTATATCAGAGATACGGGC
ACCCATTACTGCTTCCCATGCCAACAGCAGATTTATCTGTGACCATCCCAGAAACTTAACCGATCAACAAATTCGAGTTA
TTTCCGAAAGCGGAGGAGTTATAGGGGTTACCTATGTGCCTCAGTTTATTGATCTAAGTAAACCGTCTATTGAACGGCTC
ATTGAGCATATTGACCATATCTATGAGGTGGGAGGAATCTCTTGTATCGGACTAGGCTCTGATTTTGACGGCATTGATGC
GACTGTAGAGGGTCTACATGATGCAAGTATAGCAGTTCCTAATTTAGAAAATGCCCTTATAAAAAAGGGTTACACCACTG
GTGAAATCGAAAAGATAATGGGTGAGAACTGGTTAAGGGTATTTAAAGAGGTATGCGGTTAA

Upstream 100 bases:

>100_bases
AGTTAGTTCGGTACAACCTGTTTGCAAAAATAGCAAACAGGTTTCTTGCTTACTAGTGGTATTAAATTGATAACGAAGGT
GGTAGGAAAGGAGGGGCATG

Downstream 100 bases:

>100_bases
TCCTATACAAAGGAAAGCTGTTATATTGAATATAAATGAATGGTAATAATGTATAGAAAAAAGACGGTGATATTCATGCA
GTATGCCGATTTACATATTC

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLIVDAHCDTLTVLTPQGRDLGTLSQRGHIDIPRLYRGGINVQFFAIFIGPDNYHDPAQYTKEILKLFNKEIQRNASSLL
HARNYADIVHAYDSKKICAVLTIEGGEALKGKIEQLESYYTQGIRGLTLTWNGRNELGDGVGLGPEASGLTVFGRQVIQK
MVELGMMIDVSHLSEAGFWDVISEIRAPITASHANSRFICDHPRNLTDQQIRVISESGGVIGVTYVPQFIDLSKPSIERL
IEHIDHIYEVGGISCIGLGSDFDGIDATVEGLHDASIAVPNLENALIKKGYTTGEIEKIMGENWLRVFKEVCG

Sequences:

>Translated_313_residues
MLIVDAHCDTLTVLTPQGRDLGTLSQRGHIDIPRLYRGGINVQFFAIFIGPDNYHDPAQYTKEILKLFNKEIQRNASSLL
HARNYADIVHAYDSKKICAVLTIEGGEALKGKIEQLESYYTQGIRGLTLTWNGRNELGDGVGLGPEASGLTVFGRQVIQK
MVELGMMIDVSHLSEAGFWDVISEIRAPITASHANSRFICDHPRNLTDQQIRVISESGGVIGVTYVPQFIDLSKPSIERL
IEHIDHIYEVGGISCIGLGSDFDGIDATVEGLHDASIAVPNLENALIKKGYTTGEIEKIMGENWLRVFKEVCG
>Mature_313_residues
MLIVDAHCDTLTVLTPQGRDLGTLSQRGHIDIPRLYRGGINVQFFAIFIGPDNYHDPAQYTKEILKLFNKEIQRNASSLL
HARNYADIVHAYDSKKICAVLTIEGGEALKGKIEQLESYYTQGIRGLTLTWNGRNELGDGVGLGPEASGLTVFGRQVIQK
MVELGMMIDVSHLSEAGFWDVISEIRAPITASHANSRFICDHPRNLTDQQIRVISESGGVIGVTYVPQFIDLSKPSIERL
IEHIDHIYEVGGISCIGLGSDFDGIDATVEGLHDASIAVPNLENALIKKGYTTGEIEKIMGENWLRVFKEVCG

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=291, Percent_Identity=29.553264604811, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4758190, Length=291, Percent_Identity=29.553264604811, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI11641269, Length=324, Percent_Identity=29.320987654321, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI193211608, Length=322, Percent_Identity=27.9503105590062, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI193211610, Length=322, Percent_Identity=27.9503105590062, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221475880, Length=309, Percent_Identity=32.3624595469256, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281362638, Length=295, Percent_Identity=31.864406779661, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI281362636, Length=295, Percent_Identity=31.864406779661, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI161083233, Length=293, Percent_Identity=30.0341296928328, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 34492; Mature: 34492

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00869 RENAL_DIPEPTIDASE ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVDAHCDTLTVLTPQGRDLGTLSQRGHIDIPRLYRGGINVQFFAIFIGPDNYHDPAQY
CEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCHHHH
TKEILKLFNKEIQRNASSLLHARNYADIVHAYDSKKICAVLTIEGGEALKGKIEQLESYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHH
TQGIRGLTLTWNGRNELGDGVGLGPEASGLTVFGRQVIQKMVELGMMIDVSHLSEAGFWD
HCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHHHCCCCHHH
VISEIRAPITASHANSRFICDHPRNLTDQQIRVISESGGVIGVTYVPQFIDLSKPSIERL
HHHHHCCCEEECCCCCEEEECCCCCCCHHHHEEEECCCCEEEEEECCHHHCCCCHHHHHH
IEHIDHIYEVGGISCIGLGSDFDGIDATVEGLHDASIAVPNLENALIKKGYTTGEIEKIM
HHHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCEEECCCHHHHHHHCCCCHHHHHHHH
GENWLRVFKEVCG
HHHHHHHHHHHCC
>Mature Secondary Structure
MLIVDAHCDTLTVLTPQGRDLGTLSQRGHIDIPRLYRGGINVQFFAIFIGPDNYHDPAQY
CEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCHHHH
TKEILKLFNKEIQRNASSLLHARNYADIVHAYDSKKICAVLTIEGGEALKGKIEQLESYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHH
TQGIRGLTLTWNGRNELGDGVGLGPEASGLTVFGRQVIQKMVELGMMIDVSHLSEAGFWD
HCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHHHCCCCHHH
VISEIRAPITASHANSRFICDHPRNLTDQQIRVISESGGVIGVTYVPQFIDLSKPSIERL
HHHHHCCCEEECCCCCEEEECCCCCCCHHHHEEEECCCCEEEEEECCHHHCCCCHHHHHH
IEHIDHIYEVGGISCIGLGSDFDGIDATVEGLHDASIAVPNLENALIKKGYTTGEIEKIM
HHHHHHHHHHCCEEEEECCCCCCCCHHHHHCCCCCEEECCCHHHHHHHCCCCHHHHHHHH
GENWLRVFKEVCG
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]