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The map label for this gene is (sigK [H]

Identifier: 134298861

GI number: 134298861

Start: 1051431

End: 1051787

Strand: Reverse

Name: (sigK [H]

Synonym: Dred_0997

Alternate gene names: 134298861

Gene position: 1051787-1051431 (Counterclockwise)

Preceding gene: 134298873

Following gene: 134298860

Centisome position: 29.15

GC content: 42.02

Gene sequence:

>357_bases
ATGCTATCCGGCCTTTGGACAGTTACTGTCCTGTCGGTTGTTAACGGCGTAATGGCACTGGTTTCTTATATTGCCAACAA
CACTTTTCCCCAGCCCTTAAAAGAAGTGGAAGAAGCTCGTTATTTGGCATTATTGGCTGAAGGAGATGAAATGGCAAGGA
ATATCCTAACTGAAAGAAATCTCCGCTTAGTTGCTCATATTGTGAAAAAATTTGATTCTACTGGCGAAGATGTGGATGAC
TTAATCTCCATCGGGACCATTGGATTAATTAAAGCCATTAATACCTTTAAAGCTGATAAGGGCACCCGTCTAGCAACCTA
TGCCGCCCGATGTATTGAGAATGCAATTCTCCCATAA

Upstream 100 bases:

>100_bases
TTGTAAACAACATTTCCTTTGTTGCGGCACAGGACAGACACCAAATGGAGTTCCCTTCATAACATATATTGTTGACTCAA
TTATTAGGGGGGATTCATTG

Downstream 100 bases:

>100_bases
CGGAAACATTTTACTACGCTCAAAGTGTGGATATTTTAAAAAGCTTAACGGATTTGAATTCTGTTGGCGGTAGGATTAGA
TATTACCGGTTAGCTCATGG

Product: sigma-70 region 2 domain-containing protein

Products: NA

Alternate protein names: Sigma-27; Stage IV sporulation protein CB [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLSGLWTVTVLSVVNGVMALVSYIANNTFPQPLKEVEEARYLALLAEGDEMARNILTERNLRLVAHIVKKFDSTGEDVDD
LISIGTIGLIKAINTFKADKGTRLATYAARCIENAILP

Sequences:

>Translated_118_residues
MLSGLWTVTVLSVVNGVMALVSYIANNTFPQPLKEVEEARYLALLAEGDEMARNILTERNLRLVAHIVKKFDSTGEDVDD
LISIGTIGLIKAINTFKADKGTRLATYAARCIENAILP
>Mature_118_residues
MLSGLWTVTVLSVVNGVMALVSYIANNTFPQPLKEVEEARYLALLAEGDEMARNILTERNLRLVAHIVKKFDSTGEDVDD
LISIGTIGLIKAINTFKADKGTRLATYAARCIENAILP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the mother cell [H]

COG id: COG1191

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 (log phase) 250 (stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014209
- InterPro:   IPR016263
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 12906; Mature: 12906

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00715 SIGMA70_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGLWTVTVLSVVNGVMALVSYIANNTFPQPLKEVEEARYLALLAEGDEMARNILTERN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LRLVAHIVKKFDSTGEDVDDLISIGTIGLIKAINTFKADKGTRLATYAARCIENAILP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSGLWTVTVLSVVNGVMALVSYIANNTFPQPLKEVEEARYLALLAEGDEMARNILTERN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LRLVAHIVKKFDSTGEDVDDLISIGTIGLIKAINTFKADKGTRLATYAARCIENAILP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2536191; 2105293; 2841290; 3125151; 8969508; 9384377; 2492118 [H]