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Identifier: 13358165

GI number: 13358165

Start: 748200

End: 748997

Strand: Reverse

Name: Not Available

Synonym: UU600

Alternate gene names: 13358165

Gene position: 748997-748200 (Counterclockwise)

Preceding gene: 13358166

Following gene: 13358164

Centisome position: 99.64

GC content: 22.93

Gene sequence:

>798_bases
ATGAAAGTAAAGTCATTCGCAAAAATTGATTTAGGATATAGTGTTTATAAAAAACAAAAGAATTTTACAAAACACGATTT
TGAATCAATTTTTATACTTGTTGAAAATATTTATGACGATATTGAAATTACTAAAATAGAAAAAAATATTGATGATGTTC
ATTACTACAATGAAACCAATGAAATTTATGTTTATAGCCGTTTAGTTCATAAGACATTAGAATGGATTCGTCATACTTAT
CATATTAAAAATCATTATCGAATTAATATTAAAAAAAGAATTCCAATTGGTGCAGGCTTAGGTGGTGGTTCATCAAACGC
TGCAGCCATTATGAAATATATTCTAGAATTTGAGGGTATTAAAGAAATTAATTATAAAGATGTTGTTAATAAATTAGGTG
CTGATATTCCCTTTTTTTTATCAGGCTATAAAACAGCTTATATAAGTGATTACGGAAGTGTTTTAGAGGATTTGACTGGT
CAATTTAAATTAAATTATGAAGTTTATTTAATGAATGTTAATGTAAATACAAAAATTGTTTTTGAAAAATTTGATGATAA
TTCATGACATGTTATTAAAAATAATTTTAAAACAATTATTAAAAATTTAAAAGAAAATATTGTAGTTAACATACATAATG
ATCTACAAGAATACTGTTTTGAGCTATACCCTAATATTAAATACAAATATAATGAATTATTATCCGATGGTTTTTATACA
ATTTTAAGTGGTGCAGGTAGTTCATTTATTCGCATAAAATTAAAAAATAAGGAAGATTTAATTATTAATGAAAATTAG

Upstream 100 bases:

>100_bases
GAATTTACGAGCTGAAAACATTGAACCAAAAATGTTTCTAAAACTCTTTAATTATTTGAATAGATAAGATAATTAATAAA
ATTAAGTTGTAGGTCAAATT

Downstream 100 bases:

>100_bases
AACACGTTATGCTCCATCACCAACCGGTTATTTACATATTGGAGGAGCGCGAACAGCTTTATTTAATTATTTACTAGCAA
AAGCTTATGGTGGGGATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETNEIYVYSRLVHKTLEWIRHTY
HIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGIKEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTG
QFKLNYEVYLMNVNVNTKIVFEKFDDNSWHVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYT
ILSGAGSSFIRIKLKNKEDLIINEN

Sequences:

>Translated_265_residues
MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETNEIYVYSRLVHKTLEWIRHTY
HIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGIKEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTG
QFKLNYEVYLMNVNVNTKIVFEKFDDNS*HVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYT
ILSGAGSSFIRIKLKNKEDLIINEN
>Mature_265_residues
MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETNEIYVYSRLVHKTLEWIRHTY
HIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGIKEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTG
QFKLNYEVYLMNVNVNTKIVFEKFDDNS*HVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYT
ILSGAGSSFIRIKLKNKEDLIINEN

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30897; Mature: 30897

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETN
CCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCC
EIYVYSRLVHKTLEWIRHTYHIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGI
CEEEHHHHHHHHHHHHHHHHEECCEEEEEEEEECCEECCCCCCCCCHHHHHHHHHHHCCC
KEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTGQFKLNYEVYLMNVNVNTKIV
CCCCHHHHHHHHCCCCCEECCCCCEEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEE
FEKFDDNSHVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYTI
EEEECCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHCCCCEEHHHHHHHCCHHEE
LSGAGSSFIRIKLKNKEDLIINEN
HHCCCCEEEEEEECCCCCEEEECC
>Mature Secondary Structure
MKVKSFAKIDLGYSVYKKQKNFTKHDFESIFILVENIYDDIEITKIEKNIDDVHYYNETN
CCCCCCEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCC
EIYVYSRLVHKTLEWIRHTYHIKNHYRINIKKRIPIGAGLGGGSSNAAAIMKYILEFEGI
CEEEHHHHHHHHHHHHHHHHEECCEEEEEEEEECCEECCCCCCCCCHHHHHHHHHHHCCC
KEINYKDVVNKLGADIPFFLSGYKTAYISDYGSVLEDLTGQFKLNYEVYLMNVNVNTKIV
CCCCHHHHHHHHCCCCCEECCCCCEEEHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEE
FEKFDDNSHVIKNNFKTIIKNLKENIVVNIHNDLQEYCFELYPNIKYKYNELLSDGFYTI
EEEECCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHCCCCEEHHHHHHHCCHHEE
LSGAGSSFIRIKLKNKEDLIINEN
HHCCCCEEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA