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The map label for this gene is kdgR [H]

Identifier: 126700626

GI number: 126700626

Start: 3490365

End: 3491141

Strand: Direct

Name: kdgR [H]

Synonym: CD3005

Alternate gene names: 126700626

Gene position: 3490365-3491141 (Clockwise)

Preceding gene: 126700617

Following gene: 126700627

Centisome position: 81.36

GC content: 30.63

Gene sequence:

>777_bases
ATGACTTCAGATAATCATCGCCCAACAGCTAGGATATTAGATATTTTAGAAGCATTAGCAGAATCCGAAAATGGATATAC
TCTTACAGAAATAGCAGATGTTATCAATGCTCCAAAAAGTAGCATCTTTCCTATAGTTCATACACTTAATGCTAGAAAAT
ACATTACTATTGATAAAAACACATCCAAATATTCTATAGGGATACGTTCTTACACATTAGGGTCTTCATTTTTTGAAAAA
AGAACTATTTTTAACTATATAATTGACGAAATGACTAATATAGTTAATTCCTGTTCTGAAACTTGTCAGCTTGGTATACT
TGACAATAATGAAGTTCTTTATATTGGAAAAGTAGATTCTCCAGAACCGATTAGACTTATTTCTTATGTTGGAAAAAAAA
TACCTGCTAATTGTACAGGTCTTGGAAAAGCTCTTTTATGTGATTTTGACAAGGAAAAACTAATAAGCTTATATCCAGAT
GGTCTAAAAGGTTTTACAGAAAAATCAATTACAGATTTTGATGTTTTATACGACCAGCTTCTTGAAGTTCAAAGAACACA
AATAGCTTCAGAGTGTGAGGAATCAATGGAACACCTAAAATGTCTTGCCGTACCAATAAGAAAAAATGGATGTATAAGAG
CTGCTGTTAGTGTAACACTGCCTTTATTTAGAGCTAATGACGAAAAAATAGAACTGATAAAAAAATTACTCTTAAATGCT
CAGAAAAATATTCAATCAATGATGGAAGAACGTAATGAAGACATTGTAATAAATTAG

Upstream 100 bases:

>100_bases
ATAAATTTACATATTTATTTTCTACATTGTAAAATATCGTATAGTGTGCTAAAATCAACATATTCTAATACTTTAAATTA
ATAAAAAGAGGGGGAAATTT

Downstream 100 bases:

>100_bases
ATTAATATTCTGTATATTGAAGATATCAAAACATAATAATTAAAAATTTTGTTTTAAACTAATGTATTTATTTGATTTAT
ACTATAAAAACAAAGTTGCT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFPIVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEK
RTIFNYIIDEMTNIVNSCSETCQLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSVTLPLFRANDEKIELIKKLLLNA
QKNIQSMMEERNEDIVIN

Sequences:

>Translated_258_residues
MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFPIVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEK
RTIFNYIIDEMTNIVNSCSETCQLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSVTLPLFRANDEKIELIKKLLLNA
QKNIQSMMEERNEDIVIN
>Mature_257_residues
TSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFPIVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKR
TIFNYIIDEMTNIVNSCSETCQLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPDG
LKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSVTLPLFRANDEKIELIKKLLLNAQ
KNIQSMMEERNEDIVIN

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=241, Percent_Identity=27.3858921161826, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082359, Length=244, Percent_Identity=25, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786715, Length=240, Percent_Identity=23.75, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786468, Length=236, Percent_Identity=24.5762711864407, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790752, Length=236, Percent_Identity=26.6949152542373, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788581, Length=241, Percent_Identity=23.6514522821577, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789999, Length=235, Percent_Identity=20.8510638297872, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29049; Mature: 28918

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFPIVHTLNARKYITIDKN
CCCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECC
TSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETCQLGILDNNEVLYIGKVDS
CCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCC
PEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPDGLKGFTEKSITDFDVLYDQL
CCHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHCCCHHHHHHHHHH
LEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSVTLPLFRANDEKIELIKKLLLNA
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHEEHHHCCCCHHHHHHHHHHHHH
QKNIQSMMEERNEDIVIN
HHHHHHHHHHCCCCEECC
>Mature Secondary Structure 
TSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFPIVHTLNARKYITIDKN
CCCCCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECC
TSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETCQLGILDNNEVLYIGKVDS
CCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCC
PEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPDGLKGFTEKSITDFDVLYDQL
CCHHHHHHHHCCCCCCCCCCCCHHHHCCCCHHHHHHHCCCCCCCCHHCCCHHHHHHHHHH
LEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSVTLPLFRANDEKIELIKKLLLNA
HHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHEEHHHCCCCHHHHHHHHHHHHH
QKNIQSMMEERNEDIVIN
HHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]