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The map label for this gene is gmr [H]

Identifier: 126700503

GI number: 126700503

Start: 3375865

End: 3377019

Strand: Direct

Name: gmr [H]

Synonym: CD2887

Alternate gene names: 126700503

Gene position: 3375865-3377019 (Clockwise)

Preceding gene: 126700495

Following gene: 126700543

Centisome position: 78.69

GC content: 24.07

Gene sequence:

>1155_bases
ATGAAAATAAATAAAAAATTCAATAGAGTTGATATGCAGGTTTCAATACTTACTGCAATTATTGTAATAATATCTTCCTC
ATGTGTATATTTTTTTAATTATACACTAACTTATAAGAGCATGATATACTCTTTAAGTGAGAGGTCAAAACATATCTATG
AATATGTAGAAAGAAATATTGATAAAAATACCTTTACTGAAATTAATTCTAAAGAAGACCAATCAAAAAAGTCTTATAAA
AGTTCTAAAATCCTTTTAGAATCTGTAAAAAATACTACTGGAGTCATGTATCTATATACTGCTAAAAAAACAAAAGATGG
ATCACTAGTATATGTTGTTGATGGTTTAAATTCATCTAGGAGTGATTTTAGAAATGCTGGTGATTTGATAGAAAAAGAGA
TTTGGGGAGACCTTAACAAAGCATTAGATAATCATATATTGTTACCTAAAAAGATTAAATCAACATCTTGGGGATACATA
TTTATATCGTATTTTCCTATTCACAATGATGTTGGTAAGGTTGTTGGAGTAATAGGAATTGAATTTGAAGCAAAACATCA
ATACAATACATTTAAATTTATAAGTATAGTTACACCAATAATAGCATTATTAACTTGTCTAATATCAGCATTGATTGCAG
TGATTCTATTTAAAAGAATATCTAATCCTACATATACTGATTTTGCTAATACAGATTATTTAACAGGCCTAAAAAATAGA
AATGCTTTTGAAATAGATATGAATAACTTAAACAATTCAAATCTAAAGAATCTAATATCTATCATATCAATAGATTTAGA
TGGTTTAAAAAAGATTAATGATAAATTTGGCCATCAGACAGGAGACTTATATATTAAGCAAGCAAGTAAAATTATACAAT
ATGTAATAAATAAAAAATATATAGTTTATCGTATTGGAGGTGATGAATACATAATTATTCTAAAAAATTTATCTCACAAA
GAAATAAATAATATTATAAATAATATTAATTTAAAAATAGTTGAAGAAAACTCAACTAATGAATTAAAATTATCAATGTC
TATTGGATATGCTATTTTTGATGAAAAAGTAGATGTTTCTTTATTTGATACATATCGTCGTGCAGATTCTCAAATGTATG
ATAACAAAAGGAAAATTAATAAACAATATCAATAA

Upstream 100 bases:

>100_bases
CACAAATTTGATAATATATGAATATATTATGGTGAAATTTATAGATATATATTAATTATGGGGAGATTGTGGGAGGTTCT
TTTCACAAGACATTTAAGCT

Downstream 100 bases:

>100_bases
TAAATTTAAAAAGTCTATTCTTTAAATAATAAATCATAAGAATAGACTTTTTAAATTTGTGTTTTTATAAGATAAATTAT
TTAATTAAAGTTTGTTCTTT

Product: signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYSLSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYK
SSKILLESVKNTTGVMYLYTAKKTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFKRISNPTYTDFANTDYLTGLKNR
NAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKFGHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHK
EINNIINNINLKIVEENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ

Sequences:

>Translated_384_residues
MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYSLSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYK
SSKILLESVKNTTGVMYLYTAKKTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFKRISNPTYTDFANTDYLTGLKNR
NAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKFGHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHK
EINNIINNINLKIVEENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ
>Mature_384_residues
MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYSLSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYK
SSKILLESVKNTTGVMYLYTAKKTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFKRISNPTYTDFANTDYLTGLKNR
NAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKFGHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHK
EINNIINNINLKIVEENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=158, Percent_Identity=31.0126582278481, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082007, Length=197, Percent_Identity=30.4568527918782, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=153, Percent_Identity=32.6797385620915, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081977, Length=225, Percent_Identity=28.4444444444444, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081974, Length=182, Percent_Identity=30.2197802197802, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=30.8176100628931, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787262, Length=204, Percent_Identity=25, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 44254; Mature: 44254

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYSLSERSKHIYEYVERNI
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAKKTKDGSLVYVVDGLNSSR
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCH
SDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYIFISYFPIHNDVGKVVGVIGI
HHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHCCCCCCEEEEEEEECCCCHHHHHEEEEE
EFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFKRISNPTYTDFANTDYLTGLKNR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCC
NAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKFGHQTGDLYIKQASKIIQYVINKKY
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCE
IVYRIGGDEYIIILKNLSHKEINNIINNINLKIVEENSTNELKLSMSIGYAIFDEKVDVS
EEEEECCCEEEEEEECCCHHHHHHHHCCCEEEEEECCCCCEEEEEEEECEEEECCCCCHH
LFDTYRRADSQMYDNKRKINKQYQ
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYSLSERSKHIYEYVERNI
CCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAKKTKDGSLVYVVDGLNSSR
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEECCCCCH
SDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYIFISYFPIHNDVGKVVGVIGI
HHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHCCCCCCEEEEEEEECCCCHHHHHEEEEE
EFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFKRISNPTYTDFANTDYLTGLKNR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCC
NAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKFGHQTGDLYIKQASKIIQYVINKKY
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCE
IVYRIGGDEYIIILKNLSHKEINNIINNINLKIVEENSTNELKLSMSIGYAIFDEKVDVS
EEEEECCCEEEEEEECCCHHHHHHHHCCCEEEEEECCCCCEEEEEEEECEEEECCCCCHH
LFDTYRRADSQMYDNKRKINKQYQ
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]