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The map label for this gene is yhdR [H]

Identifier: 126700444

GI number: 126700444

Start: 3300160

End: 3301359

Strand: Direct

Name: yhdR [H]

Synonym: CD2828

Alternate gene names: 126700444

Gene position: 3300160-3301359 (Clockwise)

Preceding gene: 126700439

Following gene: 126700445

Centisome position: 76.92

GC content: 28.08

Gene sequence:

>1200_bases
GTGTTACATATGATATCTAATAAAATGCAAACTTTAGTTGCAAATAGTTCTGTTATAAGAGCTATGTTTGAAGAAGGAAA
GAAACTTTCTGATATTTATGGTGAGGAAAATGTTTTTGATTTTAGTATAGGAAATCCAAGTGTTGAACCTCCAGAGACTA
TTAAAGCAGTTATAAATGATATTTTAAATGAAGAATCTCCAAATTTAGTTCATGGATATATGAACAACTCAGGATATGAG
GATGTAAGAGATGCTATTGCTGAACACATAAATAAAAAAGATGGATTAAATCTTACAAGAGAAAATTTAATTATGACTTG
TGGTGCTGCTGGTGGTCTAAATATTATTTTAAAAACTCTTTTAAATCCTGGTGATGAAGTTATTGCTTTTGCACCGTATT
TTGGTGAGTATAAAAATTATACAGAAAACTATGATGGAAAATTAATAGAAGTTCCTACAAATATAGAGACTTTTGAGCCA
GATTTAGATGCTCTAAAAAATGCTATTACTCCAAAAACAAGAGCTTTAATAATAAACACTCCAAATAATCCTACTGGTGT
CATATATTCTGAAGAATTATTAAAAAATCTTGGAGAATTATTGGATTCAAAACAAAAAGAATTTAATACAAGCATATACC
TAATTTCTGATGAGCCATATAGAGAAATAATTTATGATGGTGCCAAAGTTCCTTGTGTACTAAAATACTATAGAAATTCA
TTTATAGGATACTCTTATAGTAAATCATTATCTCTACCTGGTGAACGTATAGGATATATTGTTGCTAATGGGCAAATGGA
TGATTTTGATGATGTTATGTCTTCATTAAATGTTGCAAATAGAATACTTGGATTTGTAAATGCTCCTTCTCTTTTTCAAA
GGGTTATTGCAAGAAGTTTAGATGCAGAAGTTGATGTAAATATTTATAAAAAGAATTTTGACCTTCTATATAATAGTTTA
ATCGATATGGGATATTCTTGTGTTAAACCTAATGGTACATTCTATTTGTTCCCAAAAGCTCCAATTGAAGATGATAAAAA
ATTCTGCAATGATGCAAAACAATTTAATTTATTATTAGTACCAGGTTCTTCTTTTGGTTGTCCAGGTCATTTTAGAGTAT
CATATTGTGTATCTTATGATAAAGTTAAAAGTTCTTTACCAGCATTTGAAAAATTAGCCAAATTATATAATTTAAAATAA

Upstream 100 bases:

>100_bases
TAAAAGTTTATATTTTCAAACAAGTAATTTTTCGAAAATTGTCTAAATTCAGTAAAAATATGGTAATATATACATAAGCA
ATATAAATCTATAAAAAGGA

Downstream 100 bases:

>100_bases
CTAAATAAAAGTAATTCAAATAATTAACTACCTTAGTATAGAATACTTACATTCTATATTAAGGTAGTTTATAATTTTAT
GTACTATATTTTATACATAC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLHMISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVINDILNEESPNLVHGYMNNSGYE
DVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEP
DLDALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNS
FIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSL
IDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK

Sequences:

>Translated_399_residues
MLHMISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVINDILNEESPNLVHGYMNNSGYE
DVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEP
DLDALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNS
FIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSL
IDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK
>Mature_399_residues
MLHMISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVINDILNEESPNLVHGYMNNSGYE
DVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEP
DLDALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNS
FIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSL
IDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=349, Percent_Identity=26.0744985673352, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI95147551, Length=332, Percent_Identity=24.0963855421687, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI169881279, Length=332, Percent_Identity=24.0963855421687, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI56713256, Length=412, Percent_Identity=21.6019417475728, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI56713254, Length=415, Percent_Identity=21.9277108433735, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=402, Percent_Identity=28.8557213930348, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788722, Length=381, Percent_Identity=23.3595800524934, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=23.3766233766234, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=384, Percent_Identity=24.4791666666667, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=275, Percent_Identity=25.0909090909091, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=357, Percent_Identity=26.3305322128852, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=364, Percent_Identity=25, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859735, Length=368, Percent_Identity=26.3586956521739, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573069, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646114, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573067, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573065, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44732; Mature: 44732

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHMISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVIND
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
ILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTL
HHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
LNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLDALKNAITPKTRALIINT
CCCCCCEEEECCCHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEEC
PNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNS
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHCC
FIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSL
CCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
DAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLV
CCCEEEEEEEHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCHHHHHHCCHHHEEEEEE
PGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK
CCCCCCCCCCEEEEEEEEHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLHMISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPSVEPPETIKAVIND
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHH
ILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTL
HHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
LNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLDALKNAITPKTRALIINT
CCCCCCEEEECCCHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCEEEEEEC
PNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNS
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHCC
FIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSL
CCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
DAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLV
CCCEEEEEEEHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCHHHHHHCCHHHEEEEEE
PGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK
CCCCCCCCCCEEEEEEEEHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]