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The map label for this gene is yybE [H]

Identifier: 126700351

GI number: 126700351

Start: 3174212

End: 3175081

Strand: Direct

Name: yybE [H]

Synonym: CD2736

Alternate gene names: 126700351

Gene position: 3174212-3175081 (Clockwise)

Preceding gene: 126700349

Following gene: 126700368

Centisome position: 73.99

GC content: 29.43

Gene sequence:

>870_bases
ATGGATTTATTGCATCTTAAGTATTTTCAAACTGTTGCTAGAATGGAGCACATAACAAAAGCATCACACAAGTTAAATAT
AGCACAGCCAGCTTTAAGCAAAACTATATCTTCCTTAGAAAAAGAACTTGGAGTTCAGTTATTTGACAGAAAAGGAAGAT
ATATTGTTTTAAATGAGTATGGAAGATTGTTTTTAAAAAGAGTAGATAGCATTTTAGATTTAGTAGAAAGTTCAAAAAAG
GAGTTACAAGACACTTCTTTGGAAAATTCAGGAGAAGTAAAGATATTATCTCCTGCAGCGGCTAATGTGTTACCATCACT
TTTGAGTAATTTCAGAAAACTATATCCCAATATTACTTTTAATGTGTCACATACTTTGCCATCATCTTATAAAAAAAGTG
ATTTTGATTTGTACATATCTTCTTCATTTACAAAGCTAAACTCAGAAAATAGCATAACTTTAACATGCGAAGAAATACTA
TTAGGAGTTTCAATAAACCATCCTTTATCATTAAAGGATGAAGTATATCTAAGCGAAGTTTCAGATGAAAACTTTATAGT
TATAACGAAGGGTGAGAATTATAGAGAGGTAATTGATATCCTGTGCGAATCAGCTAATTTCAAACCCAAAATAGCATTTG
AGTCTGATTCACCATATACAATTTATGCTCTTATAAAATCACTTCAAGGAGTTGGATTTATATGTGGAAAATCATGGGGA
TTATCTCAAGACCCTGAGATTAAGTTGTTACATATCAAAGATATTGAATTTAAAAGATATTTAAATCTTTCATGGTTTAG
CGAAAACTATGAATCTAAAGCTGTGTTGTTGTTCAAAAACTTTCTTATCAACTATTTTAAAAATATTTAA

Upstream 100 bases:

>100_bases
TGTAGTTTATTATATAAACTTTATATTATAATGTATAATGTGGAGTTGATTATAAAATTGATATAACTCAAGTCATATTA
AAAGAGGTGTATTTTATACT

Downstream 100 bases:

>100_bases
ATCAAAGTTGATAATATTAAAGAGGATATATCAAAGTATAATAAATTTAATCTTAATATTGATACATCCTCTTTTTATCA
TTTTATATTGAACTTGTATT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELGVQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKK
ELQDTSLENSGEVKILSPAAANVLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSPYTIYALIKSLQGVGFICGKSWG
LSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVLLFKNFLINYFKNI

Sequences:

>Translated_289_residues
MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELGVQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKK
ELQDTSLENSGEVKILSPAAANVLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSPYTIYALIKSLQGVGFICGKSWG
LSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVLLFKNFLINYFKNI
>Mature_289_residues
MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELGVQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKK
ELQDTSLENSGEVKILSPAAANVLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSPYTIYALIKSLQGVGFICGKSWG
LSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVLLFKNFLINYFKNI

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=30.8695652173913, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=25.503355704698, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789204, Length=243, Percent_Identity=26.7489711934156, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=30.8755760368664, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=265, Percent_Identity=23.3962264150943, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.4813278008299, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788887, Length=191, Percent_Identity=26.1780104712042, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790399, Length=240, Percent_Identity=22.9166666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=24.2798353909465, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787601, Length=120, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=238, Percent_Identity=24.3697478991597, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=23.3898305084746, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788297, Length=241, Percent_Identity=24.896265560166, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786401, Length=120, Percent_Identity=30, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=117, Percent_Identity=31.6239316239316, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33031; Mature: 33031

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELGVQLFDRKGRYIVLNEY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCEEEECHH
GRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAANVLPSLLSNFRKLYPNITF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEE
NVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEILLGVSINHPLSLKDEVYLSEV
EEECCCCCCCCCCCEEEEEECCEEECCCCCCEEEEHHHEEEEECCCCCCCCCCCEEEEEC
SDENFIVITKGENYREVIDILCESANFKPKIAFESDSPYTIYALIKSLQGVGFICGKSWG
CCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHCCCEEEECCCCC
LSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVLLFKNFLINYFKNI
CCCCCCEEEEEEECCCHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELGVQLFDRKGRYIVLNEY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEECCCCCEEEECHH
GRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAANVLPSLLSNFRKLYPNITF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEE
NVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEILLGVSINHPLSLKDEVYLSEV
EEECCCCCCCCCCCEEEEEECCEEECCCCCCEEEEHHHEEEEECCCCCCCCCCCEEEEEC
SDENFIVITKGENYREVIDILCESANFKPKIAFESDSPYTIYALIKSLQGVGFICGKSWG
CCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHCCCEEEECCCCC
LSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVLLFKNFLINYFKNI
CCCCCCEEEEEEECCCHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]