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The map label for this gene is manP [H]

Identifier: 126700186

GI number: 126700186

Start: 2969118

End: 2969426

Strand: Direct

Name: manP [H]

Synonym: CD2567

Alternate gene names: 126700186

Gene position: 2969118-2969426 (Clockwise)

Preceding gene: 126700185

Following gene: 126700187

Centisome position: 69.21

GC content: 33.98

Gene sequence:

>309_bases
ATGAAAATAGTAGCTATAACATCATGTATAGCAGGATTAGCACACACACCTATGGCAGCAAAAGCTTTAGAACAAGCTGC
ATCAAAAATGGGTCATGAAATCAAAGTAGAACAACAAGGTGCTATGGGACGAGTAAATACTATAACAAAAGAAGAAGCAC
AAGATGCGGACTTTATACTTATAGCATCTGACCAAACTATATCTGGAATGGAAAGATTTGATGGTAAAAAAGTGATAAAA
GTCAAAATAGGTATAGCGTTAAAAAAACCAGAAGCTGTCTTAACAAAGTGTATAGAAGCTATTTCTTAA

Upstream 100 bases:

>100_bases
CATGTTTAATGGAGGATGATTTTACAAGTGAAGTTAAAAATGCTAGTGATGCAAGTCATTTAGTAAAATATATAACTAAT
AAAATGAAGGAGGAATAATT

Downstream 100 bases:

>100_bases
TAAAAAAATCTCACTCTAATATAGAATGAGAAAAATCAAAAATTAAAAAATTGTCTAATGTAATTATAACATATTATCAA
AAAATATAACAAACTTATAT

Product: PTS system transporter subunit IIB

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGRVNTITKEEAQDADFILIASDQTISGMERFDGKKVIK
VKIGIALKKPEAVLTKCIEAIS

Sequences:

>Translated_102_residues
MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGRVNTITKEEAQDADFILIASDQTISGMERFDGKKVIK
VKIGIALKKPEAVLTKCIEAIS
>Mature_102_residues
MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGRVNTITKEEAQDADFILIASDQTISGMERFDGKKVIK
VKIGIALKKPEAVLTKCIEAIS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=99, Percent_Identity=46.4646464646465, Blast_Score=89, Evalue=5e-20,
Organism=Escherichia coli, GI87082348, Length=98, Percent_Identity=45.9183673469388, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1788492, Length=88, Percent_Identity=43.1818181818182, Blast_Score=77, Evalue=2e-16,
Organism=Escherichia coli, GI1790390, Length=93, Percent_Identity=34.4086021505376, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1788730, Length=101, Percent_Identity=36.6336633663366, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1786951, Length=96, Percent_Identity=35.4166666666667, Blast_Score=65, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 10881; Mature: 10881

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGRVNTITKEEAQDADFIL
CEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
IASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
EECCCCCCHHHHCCCCEEEEEEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGRVNTITKEEAQDADFIL
CEEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
IASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
EECCCCCCHHHHCCCCEEEEEEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]