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The map label for this gene is hrsA [H]

Identifier: 126700185

GI number: 126700185

Start: 2968663

End: 2969115

Strand: Direct

Name: hrsA [H]

Synonym: CD2566

Alternate gene names: 126700185

Gene position: 2968663-2969115 (Clockwise)

Preceding gene: 126700183

Following gene: 126700186

Centisome position: 69.2

GC content: 27.59

Gene sequence:

>453_bases
ATGGTACTACAAGAAAAATATATATTTATAGATAAAGACTTAAAAAGCAAAGAAGAAGTATTAAATTTTATTGCAGATAG
TGCTTATATACTAGGTATTACAACTAATAAAGAGGCTCTTTTAAAAGACCTTCTAAAAAGAGAAAATGAATTTCCAACAG
GAATAAAAGATGGATTTGCGATACCTCATACAAAGAGTGTAAATGTAAAGGAAGCTTCCATACTCTATATTAAAACAACT
AACGAGTTAGAGTGGAAAACTTTAGATGATAGTAAGGTTAGATATGTATTTAGTTTGTTAGCCCCACATAAAAATGAAGG
AAATATACATTTGAAAACTCTATCTAAATTAGCCACATGTTTAATGGAGGATGATTTTACAAGTGAAGTTAAAAATGCTA
GTGATGCAAGTCATTTAGTAAAATATATAACTAATAAAATGAAGGAGGAATAA

Upstream 100 bases:

>100_bases
TTTCCATGTCGAAGTGGAAATTAGTTATATTTAATTTAATTAGGATAATGATTACAATATAAATATAAGTTAAGACATTA
TGAATGGAGTGGAAAAATAT

Downstream 100 bases:

>100_bases
TTATGAAAATAGTAGCTATAACATCATGTATAGCAGGATTAGCACACACACCTATGGCAGCAAAAGCTTTAGAACAAGCT
GCATCAAAAATGGGTCATGA

Product: PTS system transporter subunit IIA

Products: NA

Alternate protein names: Putative PTS system EIIABC component; Phosphotransferase enzyme IIA component; PTS system EIIA component; Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDLLKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTT
NELEWKTLDDSKVRYVFSLLAPHKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE

Sequences:

>Translated_150_residues
MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDLLKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTT
NELEWKTLDDSKVRYVFSLLAPHKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE
>Mature_150_residues
MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDLLKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTT
NELEWKTLDDSKVRYVFSLLAPHKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=138, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI48994992, Length=141, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788726, Length=140, Percent_Identity=30, Blast_Score=69, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17155; Mature: 17155

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDLLKRENEFPTGIKDGFA
CCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
IPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAPHKNEGNIHLKTLSKLATC
CCCCCCCCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
LMEDDFTSEVKNASDASHLVKYITNKMKEE
HHCCCHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDLLKRENEFPTGIKDGFA
CCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
IPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAPHKNEGNIHLKTLSKLATC
CCCCCCCCCCCEEEEEEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHH
LMEDDFTSEVKNASDASHLVKYITNKMKEE
HHCCCHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9063979; 9278503; 8905232 [H]