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The map label for this gene is glnS

Identifier: 126699676

GI number: 126699676

Start: 2373865

End: 2375529

Strand: Direct

Name: glnS

Synonym: CD2059

Alternate gene names: 126699676

Gene position: 2373865-2375529 (Clockwise)

Preceding gene: 126699668

Following gene: 126699681

Centisome position: 55.33

GC content: 30.75

Gene sequence:

>1665_bases
ATGTCAAATGAAACGAACTCATCTAACTTTATAAAGAATATTATTATAAACGACTTAGAAACAGGAAAACATGACAGTAT
CATAACTCGTTTTCCACCTGAGCCAAACGGATATTTACATATTGGTCATGCAAAAAGTATATGTCTTAATTTTGGATTAG
CTAAGGAGTTTAATGGAAAAGCTAATTTAAGATTTGATGATACAAACCCATTAAAAGAGGATGTTGAATATGTAGAGTCC
ATAAAAGAAGATGTAAAGTGGTTAGGATTTGATTGGAACGAGTTAAATTTTGCATCTAACTACTTTGATGAAATGTATAA
GAGAGCTTTAATACTAATAAAAAAGGGTAAAGCTTATGTATGTGATTTGACACAAGAGGAAATGAGAGAATATCGTGGTA
CTCTAACTGAACCAGGAAAAGAAAGTCCTCATAGAAACAGAACTATTGAAGAAAACCTTGATTTATTTGAAAGAATGAAA
AATGGTGAATTTAAAGATGGTGAAAAAACATTAAGAGCCAAAATAGATATGTCTTCTCCAAATATAAACCTTAGAGACCC
AATTATATATAGAATATCTCATTCAACACACCATAATACAGGAGATAAATGGTGCATATATCCTATGTATGCTTTTGCTC
ATCCAATTGAAGATGCAATTGAAGGAATAACTCACTCTATATGTACTTTAGAGTTTGAAGACCAAAGACCTCTTTATGAT
TGGTTTGTTAAAGAATGTGAGATGGAAAATATACCTAGACAAATAGAATTTGCTAGACTTAATATAAATAATACTGTCAT
GAGTAAAAGGAAATTAAAACAACTTGTAGATGAGGGTATTGTTGATGGTTGGGATGACCCTCGTGTTCCTACAATATCCG
GAATCAGACGTAAGGGATATACTGCAGAAGCATTGCGCAATTTCTGTAGTGAAATAGGGGTATCAAAAGTTAACTCTACG
GTAGATAGTCAAATGCTTGATTATTTCCTAAGAGAAAACTTACAACCAAAGGCTCCTCTTACTATGGGAGTTTTAAGACC
TTTAAAACTTATTATAACTAATTACCCAGAAGATAAGATTGAGATGCTTGAAATAGAGAATAATGCTAAAGATGAATCTC
AAGGAAAGAGATTAGTTCCTTTCTCTAGAGAATTGTATATAGAACAAGATGATTTTATGGAAGAACCTGTTAAGAAATAT
TTTAGATTTTTCCCAGGAAATGAAGTCCGTTTAAAAGGTGCTTATTTTGTAAAATGTACTGATGTAATTAAGGATGAAAA
TGGAAATGTAGTTGAAATACATGGTACTTATGACCCTGAAACTAAGAGTGGCTCTGGCTTTACAGGACGTAAGGTAAAAT
CTACAATACATTGGGTTGATGCTAAATCAGCTATACCATGTGAATTTAGATTATTTGAACCATTAATTCTTGATGATATA
CCTGAAAATGAAGGTAAACATTTCTTAGAACAAATAAATCCTAATTCATTGGAAATATTACAAGGTTTTGTTGAACCTAC
ACAGATAAAAGATGCTAAACCTTTTGATAAATTCCAATTTGTTAGAAATGGATTCTTTAGTATAGATAATAAATATACAA
CTGATGAAAAATTTGTATTTAATAGAATAGTTCCTCTAAAAAGTTCTTTTAAACCAGGTAAATAA

Upstream 100 bases:

>100_bases
ATTACACCTTTATTTTTTTCTAATCTTGGATTAAAATTAATATTATGCAATACAGTGTAGTGTTCTGTATTATAATCAAA
TTAAATAGGAGGTATAGAAT

Downstream 100 bases:

>100_bases
TCTTACAATCAAAAAATGAAGACTTAAAATATAAATTACTTCTACTATAAATAAACTTAGTTAGAAGTAATTTTTTATTT
GAGTCTTCATCATTTACTTT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHAKSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVES
IKEDVKWLGFDWNELNFASNYFDEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIEDAIEGITHSICTLEFEDQRPLYD
WFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLVDEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNST
VDSQMLDYFLRENLQPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDFMEEPVKKY
FRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGRKVKSTIHWVDAKSAIPCEFRLFEPLILDDI
PENEGKHFLEQINPNSLEILQGFVEPTQIKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK

Sequences:

>Translated_554_residues
MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHAKSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVES
IKEDVKWLGFDWNELNFASNYFDEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIEDAIEGITHSICTLEFEDQRPLYD
WFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLVDEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNST
VDSQMLDYFLRENLQPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDFMEEPVKKY
FRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGRKVKSTIHWVDAKSAIPCEFRLFEPLILDDI
PENEGKHFLEQINPNSLEILQGFVEPTQIKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK
>Mature_553_residues
SNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHAKSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESI
KEDVKWLGFDWNELNFASNYFDEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMKN
GEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIEDAIEGITHSICTLEFEDQRPLYDW
FVKECEMENIPRQIEFARLNINNTVMSKRKLKQLVDEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTV
DSQMLDYFLRENLQPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDFMEEPVKKYF
RFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGRKVKSTIHWVDAKSAIPCEFRLFEPLILDDIP
ENEGKHFLEQINPNSLEILQGFVEPTQIKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4826960, Length=547, Percent_Identity=42.2303473491773, Blast_Score=411, Evalue=1e-114,
Organism=Homo sapiens, GI62241042, Length=520, Percent_Identity=35.5769230769231, Blast_Score=285, Evalue=6e-77,
Organism=Escherichia coli, GI1786895, Length=548, Percent_Identity=54.3795620437956, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1788743, Length=323, Percent_Identity=25.6965944272446, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=537, Percent_Identity=40.2234636871508, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17511007, Length=528, Percent_Identity=33.7121212121212, Blast_Score=253, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6324742, Length=561, Percent_Identity=40.4634581105169, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321192, Length=559, Percent_Identity=35.9570661896243, Blast_Score=313, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6324540, Length=312, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864488, Length=526, Percent_Identity=41.4448669201521, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24649466, Length=519, Percent_Identity=36.4161849710983, Blast_Score=290, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24665321, Length=313, Percent_Identity=26.1980830670927, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYQ_CLOD6 (Q188C8)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001088573.1
- ProteinModelPortal:   Q188C8
- SMR:   Q188C8
- STRING:   Q188C8
- GeneID:   4915499
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD2059
- NMPDR:   fig|1496.1.peg.2720
- eggNOG:   COG0008
- HOGENOM:   HBG334108
- OMA:   RMPTIAG
- ProtClustDB:   PRK05347
- GO:   GO:0005737
- HAMAP:   MF_00126
- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:2.40.240.10
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119:SF3
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00440

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C; SSF50715 Ribosomal_L25rel

EC number: =6.1.1.18

Molecular weight: Translated: 64282; Mature: 64150

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 269-269

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHAKSICLNFGLAKEFNGK
CCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHCCCHHCCCCC
ANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYFDEMYKRALILIKKGKAYV
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEE
CDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMKNGEFKDGEKTLRAKIDMSSP
ECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
NINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIEDAIEGITHSICTLEFEDQRPLYD
CCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHH
WFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLVDEGIVDGWDDPRVPTISGIRRKGY
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC
TAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENLQPKAPLTMGVLRPLKLIITNYPEDKI
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCE
EMLEIENNAKDESQGKRLVPFSRELYIEQDDFMEEPVKKYFRFFPGNEVRLKGAYFVKCT
EEEEECCCCCCHHCCCEECCCCHHEEECCHHHHHHHHHHHHHHCCCCEEEECCEEEEEEE
DVIKDENGNVVEIHGTYDPETKSGSGFTGRKVKSTIHWVDAKSAIPCEFRLFEPLILDDI
EHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCCCEECCCHHHCCC
PENEGKHFLEQINPNSLEILQGFVEPTQIKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVF
CCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCHHHHH
NRIVPLKSSFKPGK
HHCCCCCCCCCCCC
>Mature Secondary Structure 
SNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHAKSICLNFGLAKEFNGK
CCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEECCHHHHHHHCCCHHCCCCC
ANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYFDEMYKRALILIKKGKAYV
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEE
CDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMKNGEFKDGEKTLRAKIDMSSP
ECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
NINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIEDAIEGITHSICTLEFEDQRPLYD
CCCCCCCEEEEEECCCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHEEEEECCCCCHHH
WFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLVDEGIVDGWDDPRVPTISGIRRKGY
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC
TAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENLQPKAPLTMGVLRPLKLIITNYPEDKI
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCE
EMLEIENNAKDESQGKRLVPFSRELYIEQDDFMEEPVKKYFRFFPGNEVRLKGAYFVKCT
EEEEECCCCCCHHCCCEECCCCHHEEECCHHHHHHHHHHHHHHCCCCEEEECCEEEEEEE
DVIKDENGNVVEIHGTYDPETKSGSGFTGRKVKSTIHWVDAKSAIPCEFRLFEPLILDDI
EHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCCCEECCCHHHCCC
PENEGKHFLEQINPNSLEILQGFVEPTQIKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVF
CCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEECCCCCCCCHHHHH
NRIVPLKSSFKPGK
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA