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The map label for this gene is kdpE [H]

Identifier: 126699438

GI number: 126699438

Start: 2118785

End: 2119483

Strand: Direct

Name: kdpE [H]

Synonym: CD1830

Alternate gene names: 126699438

Gene position: 2118785-2119483 (Clockwise)

Preceding gene: 126699437

Following gene: 126699439

Centisome position: 49.39

GC content: 30.76

Gene sequence:

>699_bases
ATGAGTAAAAAACTTATATTGTTAGTAGAGGATGATAAGACAATAAGAAAATTTATATCTACTGCACTTTTAACACAGGA
TTATGATGTCAAGGAGGCTATAACTGGAAAAGAAGGTATATCTATTGCTGTCTCATATTCTCCAGATGTTGTTCTTTTAG
ATTTAGGCTTAGAAGATATGGATGGAATAGAGGTAATAAAAGCTATCAGACAATTTTCAAATATACCAATAATTGTAGTT
TCAGCTAGAGAGCAAGATAGAGACAAGGTAGAAGTATTTGATGCAGGGGCAGATGATTACTTAACAAAACCATTCTCTAT
AGTAGAGTTATTAGCAAGAGTAAGAGTAGCATTTAGACATTCACAAGTAGAAGCTCAACAAAAAGATGATGTTAAATCTA
CGTTTGAAGTAGATAAATTATTGATTGATTTTGATAAAAGAAAAGTTATTGTTGATGATGTTGAAGTCCATTTGACACCT
ATTGAATATAATATTCTTTCATTACTTGCAAAGCATCATGGAAAAGTGCTTACTCATAATTTTATAATAAAAGAAATATG
GGGTAGTGTTATAGGGAATGAGACTAAGTCTTTAAGGGTCTTTATGGCAACGTTAAGACGAAAAATAGAAAAACAACCTG
CAAACCCAAGATATATAATTACAGAAGTTGGTGTAGGATACAGATTAAATGATGAATAG

Upstream 100 bases:

>100_bases
TATGGTAGAAAACAATAAAGATAAGGGTTCAACTTTTAAGTTTAGTTTGCCTAAGGAAAATGAATAGTTTTAAATTTTAA
AATTAGTTTTGGAGGAAGAA

Downstream 100 bases:

>100_bases
TTGTAATATATTAATTATTAGATTATGTGCTTATTAATATATATTAAAATTATATAGTTTAGTTAAAATAAGAATGAAGT
GTATGTGCTTGTTGTCAGTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAVSYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVV
SAREQDRDKVEVFDAGADDYLTKPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRYIITEVGVGYRLNDE

Sequences:

>Translated_232_residues
MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAVSYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVV
SAREQDRDKVEVFDAGADDYLTKPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRYIITEVGVGYRLNDE
>Mature_231_residues
SKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAVSYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVS
AREQDRDKVEVFDAGADDYLTKPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTPI
EYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRYIITEVGVGYRLNDE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=44.1964285714286, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=32.8828828828829, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.4821428571429, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=31.5555555555556, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.9734513274336, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=30.3571428571429, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=28.695652173913, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=29.9107142857143, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=32, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=29.3859649122807, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=26.2931034482759, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=26.2931034482759, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=25.5605381165919, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=34.9056603773585, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=33.8345864661654, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26380; Mature: 26249

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAVSYSPDVVLLDLGLEDM
CCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCEEEEECCCCCC
DGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLTKPFSIVELLARVRVAFRH
CHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHH
SQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTPIEYNILSLLAKHHGKVLTHN
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECEEEEEEECHHHHHHHHHHHCCCEEHHH
FIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRYIITEVGVGYRLNDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCC
>Mature Secondary Structure 
SKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAVSYSPDVVLLDLGLEDM
CCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCEEEEECCCCCC
DGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLTKPFSIVELLARVRVAFRH
CHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHH
SQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTPIEYNILSLLAKHHGKVLTHN
HHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECEEEEEEECHHHHHHHHHHHCCCEEHHH
FIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRYIITEVGVGYRLNDE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]