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The map label for this gene is cmpR [H]

Identifier: 126699407

GI number: 126699407

Start: 2079472

End: 2080389

Strand: Direct

Name: cmpR [H]

Synonym: CD1798

Alternate gene names: 126699407

Gene position: 2079472-2080389 (Clockwise)

Preceding gene: 126699404

Following gene: 126699411

Centisome position: 48.47

GC content: 29.85

Gene sequence:

>918_bases
ATGACAATTCGTAGTCTTGAAATCTTTGTTAAGGTTGCTGAATGTGGTAAAATGAGTGAAGTAGCAAGAAATATGTATAT
TACCCAGTCATCAGTTAGCCAAGCTATTTCAGAAATAGAAAAAGAGTATGGTGTTAAGCTATTTGATAGAATTTCAAAAA
AATTATATTTAACTGAGGCAGGGAAAAAACTTCTTGGATATGGGAGGCATCTTTTAGCTGTAAATGAAGAAATGAATGAT
TGTATGAAGCATTGTGCAAAAAATATCCGTATAAGAGTTGGGGCAACAGTAACTGTTGGTACATGTGTAATAAGTCCAAT
AATGTTAGAATTATACAAGGTAAATCCTCTTATAGAACCTGAAGTATTTGTAGAAGATACAAGACTGATTGCAAAAAAAT
TACTTAATAGTGAATTAGATATTGCGATTGTAGAAGGAAAAATTAAGCACCCAGATATTGTTACAAAAAGCATTATTAAT
GATAATCTTGTACTTATATGTTCACACAAGCATGAGTTTTATAAAAGAGACTCTATAAAAGTTTCAGAACTTTCAAATCA
ACCATTAATTATGCGTGAATTGGGAAGTGGTACAAGAGCACAATTAGAAAAGCAATTAAAAGAATTAAAAATCCCAATGA
ATATTAGATGGTCATGTTATAACTCTGAAGCTATATTAAGAGCAGTTGTAGATAATTTTGGCATTGCAGTTATATCCGAA
TTACTTATTGAGGATTATTTAAAAAAGCATCTTTTGTGGGCTTGTGATATTGAAGGTATTAATTTACATAGGACATTTGA
TATTGCATATCATAGAAGCAAGTTTTTTACAGAAAATATTTCAGCATTTTTTGATATTTCAGTAGAATATGGGAAAAAAC
AAGCGAGAAAGAAGAGTAGAAGTGTAAACAGTTTATAA

Upstream 100 bases:

>100_bases
CTCTATAATAAAATTATACTTCTTGACAATATATTTGTAAAATACTAAAATATTAATAAAATCATAAGCATTTACTAATG
TTTGCTAAGGTTGTGATAAT

Downstream 100 bases:

>100_bases
TATATCTAAATAAAAATAAGAGTATATCAATATACTCTTATTTTTATTTAGATATATTAGCCTATATTAACGCCAAAATT
TTTACACAATCCTGCAAGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYGVKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMND
CMKHCAKNIRIRVGATVTVGTCVISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWSCYNSEAILRAVVDNFGIAVISE
LLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFFTENISAFFDISVEYGKKQARKKSRSVNSL

Sequences:

>Translated_305_residues
MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYGVKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMND
CMKHCAKNIRIRVGATVTVGTCVISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWSCYNSEAILRAVVDNFGIAVISE
LLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFFTENISAFFDISVEYGKKQARKKSRSVNSL
>Mature_304_residues
TIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYGVKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDC
MKHCAKNIRIRVGATVTVGTCVISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIND
NLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWSCYNSEAILRAVVDNFGIAVISEL
LIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFFTENISAFFDISVEYGKKQARKKSRSVNSL

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=28.0276816608997, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI157672245, Length=207, Percent_Identity=26.0869565217391, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=22.9508196721311, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=22.8373702422145, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=24.3027888446215, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790399, Length=304, Percent_Identity=22.3684210526316, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994962, Length=147, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=202, Percent_Identity=23.2673267326733, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=178, Percent_Identity=23.0337078651685, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=24.2914979757085, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=218, Percent_Identity=23.8532110091743, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788297, Length=244, Percent_Identity=20.9016393442623, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787530, Length=288, Percent_Identity=20.4861111111111, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34842; Mature: 34711

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYGVKLFDRISKKLYLTEA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEHHHH
GKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTCVISPIMLELYKVNPLIEP
HHHHHHCCCCEEEECHHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHHCCCCCCC
EVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIINDNLVLICSHKHEFYKRDSIK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEECCCHHHHHCCCEE
VSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWSCYNSEAILRAVVDNFGIAVISE
HHHCCCCCEEHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHH
LLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFFTENISAFFDISVEYGKKQARKKSR
HHHHHHHHHHCEEEECCCCCEEEEEEEHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHC
SVNSL
CCCCC
>Mature Secondary Structure 
TIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYGVKLFDRISKKLYLTEA
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEHHHH
GKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTCVISPIMLELYKVNPLIEP
HHHHHHCCCCEEEECHHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHHCCCCCCC
EVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIINDNLVLICSHKHEFYKRDSIK
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCCEEEEECCCHHHHHCCCEE
VSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWSCYNSEAILRAVVDNFGIAVISE
HHHCCCCCEEHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHH
LLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFFTENISAFFDISVEYGKKQARKKSR
HHHHHHHHHHCEEEECCCCCEEEEEEEHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHC
SVNSL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]