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The map label for this gene is evgS [C]

Identifier: 126699345

GI number: 126699345

Start: 2012365

End: 2014359

Strand: Direct

Name: evgS [C]

Synonym: CD1738

Alternate gene names: 126699345

Gene position: 2012365-2014359 (Clockwise)

Preceding gene: 126699344

Following gene: 126699346

Centisome position: 46.91

GC content: 25.21

Gene sequence:

>1995_bases
GTGAATAAAAAAAAGATTGTTATTATAGGGATTATTTATTCATTTTTAGTAGTATTTTCACTTACAAATATGTATGTAAA
TATGGAGTATAATTTAAATGTATTTGAATATATTAAGAAGTCACTTCCATTTACAGAAGAAGAAAAAAAGTGGTTAGAAA
AACACAAGAATTTGATTTACAGCTCTGACCAAAGTTCACCTCCTTTGAGATATAAAGGTAAGGAAGATGGACAGTATAAG
GGAATTATTGTTGATTTAATAAATTCTCTGTCAATTCAAATTGGTAGAGATTTTTATTTTAAACCAAATAATTGGTGGAA
AGAATCTTTTGTAAATTCAATAGATGATAGTATAAAGTTTTTTGACTTGATTCCATCAAAAGAAAGGGCAAATAAATTTA
TATTTACTGACCCAATATACACTTTGAGTGCAAATATATTGAAAGATAAAAAGTCCCAAGATATAAATAGTTACATGGAT
TTAAAGGGGAAAACAGTAGCAATTCCAGAAGGTGATTATTCTATAAATTTTTTAAAGCAAAAAATTCAAGATATAAACAT
TTTGTTGACTCCAGATATAAAGACTGGAGTCAACCATTTAATGTCTGGAAAAGTAGACGTAGTTGTTGGTGATGAACCAG
TATTGCGATACTATATAAATAATTATGGACTTTCAAATAAATACAGTGTTTTAAGTAATCCTATATATACTAAAAAAGCA
GTTCTTGCTGTACCTAAACAATATGAAGAGCTGGTTAGTATTTTAAATAAAGGCATTTTTAAACTTCAGAAAAATGGAGT
GTATAAAGATTTAAAGAAAAAATGGTATTCTACGTATAATGAAGTTGATGATATATTGTATGAGCGAGGAATTGTGCCTA
GTATTTATCTTTTTATAGGTATAATTTTAATATCAATTTATGTTTTTTATAGCTATACATATTTGTTAAAGATAGAAATC
AAAAGGAAAACAGAACAGGTAATAGAAAATAAAAAAACTTTAGAGGCAACTTTTAATAGTATTACAGATATAATAATGCT
TGTAGATGAAAATAACAATATAGTAGAATCGAACAAAGTACTATATGACTTTATGGGTGAAATGAGTTATAAGATAGCAG
ATTTGATTAGCATGATAAAAGGTGTTATTGAAAATACCTTCTCTGAAAATACTAATAAAACTAGTGAAATAGAAATACAC
AATAAAATTTTAAAGATAAACACTTTTCCTGTAGAGTATAAAAAAAATAATACTGAGTATATAGTAGTTCTTATTAAAGA
TATAACTAATGATAAAATAGTAGAGGCGAAATTACTTAGAGAAAACAAAATGATATCTATAGGACAATTAGCTTCTGGGG
TAGCACATGAGATAAGAAATCCTTTGGGTATAATAAGAAATAATTGCTATCTCTTAAAAGATAACGTTACAATGGAAGAA
GTAAATGATTGTGTTAAATCAATAGAAAGTAATGTAGATAGGGCAAGTAATATAATAACCAACTTGTTAAATTTTGCAAG
AATATCAGATGATAATTTAGAACATATAAATATAAAAAATTTTATTGAAAATATAGTGAAACTTCAATATAAAATGTTAC
AGTTAAAGAATGTTGAAATAAAAATTGACTGTGAACATAATTTAATATGCTATATAAATGGAGAATCGTTAAAACATGTA
TTTATAAATTTAATTTCTAATTCAATAGATGCAATACATCAAGATGGAAAAATTATTATATACTGTTATGAAAAAAATCA
TTGTTTATTTATAGATTTTAAAGATAATGGTGAAGGAATAAAAGAAGATGTCCTAAAGGACATATTTAATCCCTTCTATA
CAACAAAACCAATTGGTGAGGGAACTGGTTTAGGTTTATATATTACTTATAATGAGATTAAAAAGAATAATGGAGATATA
AGTGTTGAAAGTAAATTGGGGGTTGGAACTTGTTTTCATATAAAAATTCCATTAAATAAAGAGGTGACTATATAA

Upstream 100 bases:

>100_bases
AATTAGTTTTATAATAAATATAAATATTTAATGAAAAAAGTAGGATTTTGTTATTAAATATTGAATTTATTATAGTAAAA
AAGAAGATAGGAGTTTTAAA

Downstream 100 bases:

>100_bases
TGAAAATACTATTAGTTGATGATGAGCTAGAATATGGAGTGGTAATGAAAAAAATTCTACAAAAGAAGGGCTATCTTGTA
GATATAGCACTAAGTGGTGA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPFTEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYK
GIIVDLINSLSIQIGRDFYFKPNNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYYINNYGLSNKYSVLSNPIYTKKA
VLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWYSTYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEI
KRKTEQVIENKKTLEATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTNKTSEIEIH
NKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQLASGVAHEIRNPLGIIRNNCYLLKDNVTMEE
VNDCVKSIESNVDRASNIITNLLNFARISDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHV
FINLISNSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGLGLYITYNEIKKNNGDI
SVESKLGVGTCFHIKIPLNKEVTI

Sequences:

>Translated_664_residues
MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPFTEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYK
GIIVDLINSLSIQIGRDFYFKPNNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYYINNYGLSNKYSVLSNPIYTKKA
VLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWYSTYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEI
KRKTEQVIENKKTLEATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTNKTSEIEIH
NKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQLASGVAHEIRNPLGIIRNNCYLLKDNVTMEE
VNDCVKSIESNVDRASNIITNLLNFARISDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHV
FINLISNSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGLGLYITYNEIKKNNGDI
SVESKLGVGTCFHIKIPLNKEVTI
>Mature_664_residues
MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPFTEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYK
GIIVDLINSLSIQIGRDFYFKPNNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYYINNYGLSNKYSVLSNPIYTKKA
VLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWYSTYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEI
KRKTEQVIENKKTLEATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTNKTSEIEIH
NKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQLASGVAHEIRNPLGIIRNNCYLLKDNVTMEE
VNDCVKSIESNVDRASNIITNLLNFARISDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHV
FINLISNSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGLGLYITYNEIKKNNGDI
SVESKLGVGTCFHIKIPLNKEVTI

Specific function: Member Of The Two-Component Regulatory System Evgs/Evga. Phosphorylates Evga Via A Four-Step Phosphorelay In Response To Environmental Signals. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=682, Percent_Identity=23.6070381231672, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=29.0598290598291, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=30.4878048780488, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI87081816, Length=309, Percent_Identity=23.3009708737864, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=24.9329758713137, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=27.9569892473118, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=23.7960339943343, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787031, Length=226, Percent_Identity=23.8938053097345, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=222, Percent_Identity=25.2252252252252, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788228, Length=234, Percent_Identity=24.3589743589744, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788393, Length=218, Percent_Identity=21.1009174311927, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=22.8310502283105, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786600, Length=266, Percent_Identity=20.6766917293233, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76664; Mature: 76664

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPFTEEEKKWLEKHKNLIY
CCCCEEEEEHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHCCEEE
SSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKPNNWWKESFVNSIDDSIKF
ECCCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHHCCCEE
FDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMDLKGKTVAIPEGDYSINFLKQ
EECCCCHHHCCEEEEECCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHH
KIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYYINNYGLSNKYSVLSNPIYTKKA
HHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCEEEHHHHHCCCCCCHHHHCCCCCCCHH
VLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWYSTYNEVDDILYERGIVPSIYLFIG
HEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IILISIYVFYSYTYLLKIEIKRKTEQVIENKKTLEATFNSITDIIMLVDENNNIVESNKV
HHHHHHHHHHHEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHEEEEEEEECCCCEEECCHH
LYDFMGEMSYKIADLISMIKGVIENTFSENTNKTSEIEIHNKILKINTFPVEYKKNNTEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCE
IVVLIKDITNDKIVEAKLLRENKMISIGQLASGVAHEIRNPLGIIRNNCYLLKDNVTMEE
EEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHH
VNDCVKSIESNVDRASNIITNLLNFARISDDNLEHINIKNFIENIVKLQYKMLQLKNVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHEECCEE
KIDCEHNLICYINGESLKHVFINLISNSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGI
EEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCCH
KEDVLKDIFNPFYTTKPIGEGTGLGLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCEEEEEEEECCCC
EVTI
CCCC
>Mature Secondary Structure
MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPFTEEEKKWLEKHKNLIY
CCCCEEEEEHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHCCEEE
SSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKPNNWWKESFVNSIDDSIKF
ECCCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHHCCCEE
FDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMDLKGKTVAIPEGDYSINFLKQ
EECCCCHHHCCEEEEECCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHH
KIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYYINNYGLSNKYSVLSNPIYTKKA
HHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCEEEHHHHHCCCCCCHHHHCCCCCCCHH
VLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWYSTYNEVDDILYERGIVPSIYLFIG
HEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IILISIYVFYSYTYLLKIEIKRKTEQVIENKKTLEATFNSITDIIMLVDENNNIVESNKV
HHHHHHHHHHHEEEEEEEEEHHHHHHHHHCCHHHHHHHHHHEEEEEEEECCCCEEECCHH
LYDFMGEMSYKIADLISMIKGVIENTFSENTNKTSEIEIHNKILKINTFPVEYKKNNTEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCCE
IVVLIKDITNDKIVEAKLLRENKMISIGQLASGVAHEIRNPLGIIRNNCYLLKDNVTMEE
EEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHH
VNDCVKSIESNVDRASNIITNLLNFARISDDNLEHINIKNFIENIVKLQYKMLQLKNVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHEECCEE
KIDCEHNLICYINGESLKHVFINLISNSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGI
EEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCCH
KEDVLKDIFNPFYTTKPIGEGTGLGLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNK
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEECCCCEEEEEEEECCCC
EVTI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]