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The map label for this gene is pgm1 [H]

Identifier: 126699180

GI number: 126699180

Start: 1825729

End: 1827426

Strand: Direct

Name: pgm1 [H]

Synonym: CD1577

Alternate gene names: 126699180

Gene position: 1825729-1827426 (Clockwise)

Preceding gene: 126699179

Following gene: 126699181

Centisome position: 42.56

GC content: 29.51

Gene sequence:

>1698_bases
ATGGATTATACTAAAACTTATGAAGAGTGGATAAAGGGTTCATATTTTGATGAAGATACAAAGCTAGAGTTGGAGAATAT
AAAAAATAATGAAAAAGAAATAGAGGATAGATTCTATAAGGATTTAGAATTTGGGACTGCGGGTCTTAGAGGAATAATTG
AAGCAGGAACGAATAGAATAAATAAGTACACAGTTAGAAGAGCTACTTTTGGATTGGCAAACTATATATTAGAAAACACA
ACAAAAGAAGAAACAAGTAGAGGAGTAGTAATAGCTCATGATAATAGACACAAGTCTAGACAATTCTGTATAGAATCTGC
AAATACTTTGGCAGCATGTGGTATAAAAGCATATATATTTGATAGTTTGAGAACTACTCCAGAATTATCTTTTGCTGTTA
GAAGCTTAAACGCAATCGCTGGTATAGTCATAACAGCAAGCCATAATCCTCCAGAATATAATGGATATAAGGTATACTGG
GAAGATGGAGCACAAGTTATGCCAGAGATTGCAAATGCAATAACAGAGAAAGTAAATAGTATACATGATTATAGTACAAT
ACCAACCTTAACGGAAGCTAATAAAAATTTGGTAGTTTTGTTGGACGAATCACAAGATACTAAATTTATAGAAGCAGTAA
AAAGCCAAATTATAAGAAAAGATTTAGTTAAAAATGTAGGTAAAAGCTTTAAGATAGTTTATACACCTCTTTGTGGAACA
GGGAATGTTCCAATAAGAAGAGCATTGAAAGAAGTTGGTTTTGAAAATATAATTGTAGTTCCAGAAGAAGAAAATCCAGA
CCCAAATTTTGCAGGGCTTGATTATCCAAATCCAGAAGAGAAAAAAGCTTTAAATAGAGGTATATTACTCGCAAAAGAAA
AAGGAGCAGACCTTGTAATAGCAACTGACCCAGATTGTGATAGAGTAGGTGTAGCAGTAAAAACTACTACAGGTGAGTAT
GCTTTACTTACAGGAAATCAAATTGGTGGTATGCTGACACATTATATAATAGAAGGATTAAAAGAAAATAACAAATTAAA
AGAAAATCCTACAATAATAAAAACCATAGTTACATCAGAATTTGGAGCAGATATAGCTAAAGCAAATAATGTTGATGTAT
TAAATGTTCTTACAGGTTTTAAATTTATTGGTGAAAAAATAAAATTATTTGAACAAAATAAAAATAGAAGTTATGTATTT
GGATATGAAGAAAGTTATGGTTACTTAGTTGGGACTCATGCTAGAGATAAAGATGGTGTAGTTTCTTCATTGTTAATATC
TGAAATGGCAGCATTTTACTATTCAAAAGGTATGAGTTTATATGATGGTTTAATAGAACTTTATAAAAAGTATGGATTTT
TCAAAGAACAGACTATATCTTTGACTTTAAAAGGTATAGAAGGTGTAGAAAAGATAAAAGAAATAATATCTTATTTTAGA
GAAAATCAAATTGATTATATAAATAGTATTAAAGTAGTTGATAAAAAAGATTATAAAAATGGTATAGATAATCTTCCTAA
ATCTGATGTTTTAAAATACTTTTTGGAAGATGAATCTTGGGTAGCTATAAGACCATCTGGAACAGAACCAAAACTTAAAT
TTTACATAGCTGTAAAAGGAGCTAGTGATATTGAAGCAGATAAAAAGATTCAAGGTTTGAAAAAGTATATAGATGACATG
GTCGAAAAATTAAAATAA

Upstream 100 bases:

>100_bases
TTAATTCAATTAATAAGTATATAGAAGAGTTATAGATTACATTAAAATGCTTGTTTATGCGTCAGTTGCAATAAATACAT
ACAGTAGAGAGGGGTTTATT

Downstream 100 bases:

>100_bases
AATATTATTATTTTATAAGATAATTTTGTAATAATATTTATTTAGCTGAAAATTATAATTTACTTTCATTGAGTAGAATA
TGGAAATGTTAGTAGAATTG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRINKYTVRRATFGLANYILENT
TKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGT
GNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEY
ALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVF
GYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFR
ENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDM
VEKLK

Sequences:

>Translated_565_residues
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRINKYTVRRATFGLANYILENT
TKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGT
GNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEY
ALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVF
GYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFR
ENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDM
VEKLK
>Mature_565_residues
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRINKYTVRRATFGLANYILENT
TKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGT
GNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEY
ALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVF
GYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFR
ENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDM
VEKLK

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI31377548, Length=592, Percent_Identity=31.9256756756757, Blast_Score=266, Evalue=6e-71,
Organism=Homo sapiens, GI63055049, Length=601, Percent_Identity=30.4492512479201, Blast_Score=253, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71993870, Length=565, Percent_Identity=32.7433628318584, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI71993878, Length=298, Percent_Identity=33.5570469798658, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323934, Length=556, Percent_Identity=31.1151079136691, Blast_Score=230, Evalue=4e-61,
Organism=Drosophila melanogaster, GI20129809, Length=564, Percent_Identity=30.8510638297872, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24651977, Length=493, Percent_Identity=31.237322515213, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24653722, Length=437, Percent_Identity=30.4347826086957, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 63650; Mature: 63650

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRI
CCCCHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
NKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIF
HHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCHHHHHHHCCCHHHHCCHHHHHH
DSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYWEDGAQVMPEIANAITEKVNS
HHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGT
HHCCCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVI
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCEEEE
ATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSE
ECCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHH
FGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVFGYEESYGYLVGTHARDKDGV
HCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCHH
VSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
ENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKG
CCCCCHHHCEEEEECHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEEC
ASDIEADKKIQGLKKYIDDMVEKLK
CCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEFGTAGLRGIIEAGTNRI
CCCCHHHHHHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHH
NKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQFCIESANTLAACGIKAYIF
HHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCCHHHHHHHCCCHHHHCCHHHHHH
DSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYWEDGAQVMPEIANAITEKVNS
HHHCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
IHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQIIRKDLVKNVGKSFKIVYTPLCGT
HHCCCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
GNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYPNPEEKKALNRGILLAKEKGADLVI
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEEEECCCCEEEE
ATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTHYIIEGLKENNKLKENPTIIKTIVTSE
ECCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHH
FGADIAKANNVDVLNVLTGFKFIGEKIKLFEQNKNRSYVFGYEESYGYLVGTHARDKDGV
HCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCHH
VSSLLISEMAAFYYSKGMSLYDGLIELYKKYGFFKEQTISLTLKGIEGVEKIKEIISYFR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
ENQIDYINSIKVVDKKDYKNGIDNLPKSDVLKYFLEDESWVAIRPSGTEPKLKFYIAVKG
CCCCCHHHCEEEEECHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEEC
ASDIEADKKIQGLKKYIDDMVEKLK
CCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]