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The map label for this gene is kipA [H]

Identifier: 126698990

GI number: 126698990

Start: 1605727

End: 1606713

Strand: Direct

Name: kipA [H]

Synonym: CD1387

Alternate gene names: 126698990

Gene position: 1605727-1606713 (Clockwise)

Preceding gene: 126698989

Following gene: 126698991

Centisome position: 37.43

GC content: 32.52

Gene sequence:

>987_bases
ATGGGATTCAAAGTTGAATTAGGAGGTTTCCAAACATTAATACAAGACAGAGGTAGAGTTGGCTATGGTCAATATGGTGT
ATCTGGATGTGGAGCAATGGATGAGTATGCACATAGAGTAGGAAATATATTAGTAGGAAATTCTGAAGATGAGGCTTCCT
TAGAAGTTTTAATGTTAGGTCCTACAATTACCTTTGATGAATATACGCAAATAGCAGTAACTGGGGGAGATTTAGGGGCT
AAAATAAATGGAAAAGAAATTCAAAACTGGAGGTCATATCAAATAAATCCAGGTGATGTATTATCATTTAGAGGTGTGAA
ATCAGGTGCTAGAGCCTATGTGTCAATAGCTGGTGGAATAGATGTTCCACTTGCAATGGGAAGTAAGTCAACTTATACAA
GAGCTAAAATTGGTGGATTTGAAGGTAGAGCACTTAAAAAAGGAGATTATATAAATACTTTTATTCAGGAAAAAGATTTT
ACAATAAATAAAAAATTAAGTTCAAAATATATTCCAACTTATAGTTCAGAAATCGTACTAAGAATTGTAAAAGGTCCTCA
ATTTGATGCTTTTTCTAACGGTGAAGTAGAGAAATTTTTATCAAATAAATACAAAGTTACGAATGAAATAGATAGAATGG
GTTGTAGACTAGATGGAGAGAGTATAAAGCACCTTAATGGAGCAGATATTATATCTGATGGTATTTCTTATGGAGCTATA
CAAGTACCTGGTCATGGAAAACCGATTATAATGTTATCAGATAGACAGACTAGTGGTGGCTATACTAAGATAGGGAACGT
TATAAGTGTAGATTTGTATAAGTTAGCACAAGCAAAGCCAAATGATGTAGTAAAATTTGAACTTGTAGATATATATGAAG
CACATAGACTATTGAGAGAGCAAGAAGATAAGATTCAAGATATCTACAAGAGTATGAAAAATATAAGAGTTGTAAAGGCA
AAAGTATTAAATGATATAGCAGTTTAA

Upstream 100 bases:

>100_bases
ATTTTATAAAATTTGTTCCAATAACATTAGATGAATTTATAGAAATCGAAAAAAATAACTTAAGTATTTAAATATCGTTA
TAGTACAGGGAGTGGTATAT

Downstream 100 bases:

>100_bases
TTTAATTTTAACAAATACAATTTTTATTATAATTTATAATATAACTTACAAATAGCTATTTACTATTTACCATAATTAAG
ATGGTTTAGATTAGTCAAAT

Product: allophanate hydrolase subunit 2

Products: ADP; phosphate; urea-1-carboxylate

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGA
KINGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAI
QVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKA
KVLNDIAV

Sequences:

>Translated_328_residues
MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGA
KINGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAI
QVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKA
KVLNDIAV
>Mature_327_residues
GFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAK
INGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDFT
INKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAIQ
VPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAK
VLNDIAV

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=313, Percent_Identity=31.629392971246, Blast_Score=185, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319685, Length=319, Percent_Identity=34.7962382445141, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: 6.3.4.6

Molecular weight: Translated: 36031; Mature: 35899

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLG
CCEEEECCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEC
PTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGI
CEEEECCCEEEEEECCCCCCEECCHHHCCCCCEECCCCCEEEECCCCCCCEEEEEEECCC
DVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDFTINKKLSSKYIPTYSSEIVL
CCEEEECCCCCCCEEECCCCCCCEECCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEE
RIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAI
EEECCCCCCCCCCCCHHHHHCCCEEEHHHHHHHCCEECCHHHCCCCCCHHHHCCCCCCEE
QVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLRE
EECCCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHCCCCCCEEEEEEHHHHHHHHHHHH
QEDKIQDIYKSMKNIRVVKAKVLNDIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLG
CEEEECCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCEEEEEEC
PTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGI
CEEEECCCEEEEEECCCCCCEECCHHHCCCCCEECCCCCEEEECCCCCCCEEEEEEECCC
DVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDFTINKKLSSKYIPTYSSEIVL
CCEEEECCCCCCCEEECCCCCCCEECCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCEEE
RIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAI
EEECCCCCCCCCCCCHHHHHCCCEEEHHHHHHHCCEECCHHHCCCCCCHHHHCCCCCCEE
QVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLRE
EECCCCCEEEEEECCCCCCCCCCCCCEEEEHHHHHHCCCCCCEEEEEEHHHHHHHHHHHH
QEDKIQDIYKSMKNIRVVKAKVLNDIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; urea; CO2

Specific reaction: ATP + urea + CO2 = ADP + phosphate + urea-1-carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]