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The map label for this gene is iap [H]

Identifier: 126698969

GI number: 126698969

Start: 1582538

End: 1584067

Strand: Direct

Name: iap [H]

Synonym: CD1368

Alternate gene names: 126698969

Gene position: 1582538-1584067 (Clockwise)

Preceding gene: 126698968

Following gene: 126698970

Centisome position: 36.89

GC content: 30.52

Gene sequence:

>1530_bases
ATGATAATTAATAGGTCTAAAGATTCAAGCAGTAATGAAATTAGTTTTGTATCTAAAGATATGGGATTTTTACTTACACA
AAGTGAAGTGTCATACAATTTTAAAGATAAGTTAGTTGAAGACATAGCAAAGCAAGTATTTGCTGAAAATAGGCTTTCAG
TTGGAACAATAGCAAAGACCAATGTCAAGTATACAAAGATGTTTATAGGAGTAAATGGTTATGACACAATAATGAGTGCA
TATACAGAAGCAAGTAAAAAGACAAAGAAAAAGTATATGATAGAGGCCAATTTAGATAAGTTTAATGTTATTGAAAAAGG
AACTGTTACATTAAGTGTTATGTTTGAAGAGGGATTTAATATTATAAATACCACCTTTTCGGAGAGCATGGAAAATGTAA
AAAATAAAGTAATAGTGGTAGACCAGTATGGAAGCAAGATTAGCGAAAAAATAGATAATGAAATTTTTAAGGAAGTAAAT
GTAATAATGCAAAAAGTAATTCAGCAACAAGAAAATCAAGATGTAGATATTGATAGCGAGTTTAATGGGATAGAAAAAAG
CTGTTCTCTTAAAGGTTATGGAGATGTAAGTTGTATAACTGGTAGAGGAGTAAAAGTTAAAGATTCTTATACAAAGCTTG
TAGGACTATTTTATATAGATACAGACAAACATACTTGGCAAAATGGAGAATATCAAATTGAGCTTGAACTTAATTTTCAA
AATCTTATGGATGAAAAGTCAGCAGGACAGGATGAACCTAAGGAAGAAAGTAATTTAGGGGGAGAAGATTATGCAGGAGG
AAAAGAGTTTACAGCAGAATTTACAGCTTACTGTCCTAGAAAAGAAGAAGGTGGAGATACAGATTGTAGAAAGAAAAAAC
TTGACCCATCTAAAAAAACTTGCGCTGCTCCTATGGTTGGTAAATATGAGCAAACTTATTATACAAAAGAGTTTTTAAAT
AAACATCCTTTATTAAACTATGGAGATGAAATACAGGTAATTACAGGAGTTTCTGGTCGTGATGGAGTCTATAAAGTAAA
TGACGTAGGACCTGCAATAACTATAGAAAAGAATGGAACATACCATATAGATATTTTATTTGGAAATGTTGAAGAAGCTA
GTAAATTTGGAAGAAGAAAAGGAAAAATTATTATTGGTGGTTATTCTGGTAATGTATCTGATAAAGCTAAAATAGTAATA
TCAGAAGCAAAAAAACATCTAGGTAAACCTTATAAATGGGGTGGAAATGGACCAAGTAGTTTTGACTGTTCTGGTTTAAT
GGTCTATTGTTTTAAAAAAGTTAATGTTAGTTTGCCAAGAACGTCAAATCAACAATCTAAAAAAGGCAAGAAAGTAGAAC
AAAAAAATCTTCAAGCAGGAGATTTAGTATTTTTTCATAATCCAGTCAGCCATGTTGGATTATATATAGGTAATGGAGAA
TTTTTACATGCTCCACAGAAAGGTGATGTAGTTAAAATAAGTAAGTTAAGTAGTAGAAGAGATTTTAACACAGCTAGGAG
AGTATTATAA

Upstream 100 bases:

>100_bases
AATAATACAATCATCATTTGATGTAAATTTCCAACAAATCGATATACCAATAGCTAGTACAGTCTGTTTCTATGTAGATG
AGAAAGAACTCTTTAGAGGA

Downstream 100 bases:

>100_bases
AAGGATGGTGATATAATGGCTAATCCAATAAATGAATTTATAGGAATAATAAGAGAAGAAGGAAAGTATCATAATCAACC
TTCTTTTTTTATTGGAAAAA

Product: phage cell wall hydrolase

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSA
YTEASKKTKKKYMIEANLDKFNVIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGEYQIELELNFQ
NLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLN
KHPLLNYGDEIQVITGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKAKIVI
SEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQKNLQAGDLVFFHNPVSHVGLYIGNGE
FLHAPQKGDVVKISKLSSRRDFNTARRVL

Sequences:

>Translated_509_residues
MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSA
YTEASKKTKKKYMIEANLDKFNVIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGEYQIELELNFQ
NLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLN
KHPLLNYGDEIQVITGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKAKIVI
SEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQKNLQAGDLVFFHNPVSHVGLYIGNGE
FLHAPQKGDVVKISKLSSRRDFNTARRVL
>Mature_509_residues
MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSA
YTEASKKTKKKYMIEANLDKFNVIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGEYQIELELNFQ
NLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLN
KHPLLNYGDEIQVITGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKAKIVI
SEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQKNLQAGDLVFFHNPVSHVGLYIGNGE
FLHAPQKGDVVKISKLSSRRDFNTARRVL

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787944, Length=134, Percent_Identity=36.5671641791045, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786421, Length=132, Percent_Identity=36.3636363636364, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788501, Length=125, Percent_Identity=37.6, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788001, Length=108, Percent_Identity=34.2592592592593, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 57009; Mature: 57009

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFAENRLSVGTIAKT
CCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEC
NVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFNVIEKGTVTLSVMFEEGFN
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCEEEEEEEEECCCC
IINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVNVIMQKVIQQQENQDVDIDSE
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGEYQIELELNFQ
CCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEEEEECCCCCCCCCCEEEEEEECHH
NLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPRKEEGGDTDCRKKKLDPSKKT
HHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCCCCCHHHHCCCCCHHH
CAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVITGVSGRDGVYKVNDVGPAITIEKNGT
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEEECCCC
YHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKAKIVISEAKKHLGKPYKWGGNGPSS
EEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHHHHHCCCCCCCCCCCCCC
FDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQKNLQAGDLVFFHNPVSHVGLYIGNGE
CCCCCEEEEEEECCCEECCCCCCCHHHCCCCHHHHCCCCCCEEEEECCHHHEEEEECCCC
FLHAPQKGDVVKISKLSSRRDFNTARRVL
EEECCCCCCEEEEECCCCCCCCHHHHHCC
>Mature Secondary Structure
MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAKQVFAENRLSVGTIAKT
CCCCCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEC
NVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFNVIEKGTVTLSVMFEEGFN
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCEEEEEEEEECCCC
IINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVNVIMQKVIQQQENQDVDIDSE
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFYIDTDKHTWQNGEYQIELELNFQ
CCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEEEEECCCCCCCCCCEEEEEEECHH
NLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTAYCPRKEEGGDTDCRKKKLDPSKKT
HHHHHHHCCCCCCCHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCCCCCHHHHCCCCCHHH
CAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVITGVSGRDGVYKVNDVGPAITIEKNGT
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEEECCCC
YHIDILFGNVEEASKFGRRKGKIIIGGYSGNVSDKAKIVISEAKKHLGKPYKWGGNGPSS
EEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEHHHHHHCCCCCCCCCCCCCC
FDCSGLMVYCFKKVNVSLPRTSNQQSKKGKKVEQKNLQAGDLVFFHNPVSHVGLYIGNGE
CCCCCEEEEEEECCCEECCCCCCCHHHCCCCHHHHCCCCCCEEEEECCHHHEEEEECCCC
FLHAPQKGDVVKISKLSSRRDFNTARRVL
EEECCCCCCEEEEECCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]