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The map label for this gene is pgsA [H]

Identifier: 126698926

GI number: 126698926

Start: 1539080

End: 1539622

Strand: Direct

Name: pgsA [H]

Synonym: CD1327

Alternate gene names: 126698926

Gene position: 1539080-1539622 (Clockwise)

Preceding gene: 126698925

Following gene: 126698927

Centisome position: 35.87

GC content: 29.1

Gene sequence:

>543_bases
ATGAACTTGCCTAACAAGTTAACTTTGTTTAGAATATTTTTAATACCAGTATTTGTTTTAATTATGTTGCTCAATGTACC
AAATAAATTTTTAATAGCTTGTATTATTTTTATAATAGCTTCAATTACTGATGCTTTAGATGGAAAAATAGCTAGAAAAT
ACAATCTAGTCACTGACTTTGGAAAATTTATGGACCCATTAGCAGATAAGCTATTGGTTATTTCAGCACTTACATGTATG
ATAGAAGACCATCTTGTAAGTAGTTGGATGGTAATTATAATAGTGGCTAGAGAGCTTACAGTTAGCATATTAAGAGCTAT
AGCTGCTGCTGATGGAAAAGTAATTGCTGCTGGAAACAGTGGAAAACTTAAAACGATAACTCAAATGGTATCTATAGTGT
TTTTATTGTTAGGTGCTCAGTTTGAAAATGTATTGATATTAAATATTGGTGAAATTCTCATTCTTATAGCTACACTACTT
ACATTATATTCTGGATGGGAATATCTATATAAAAATAAAGAGCTTTTTATGTCTTCTAAGTAA

Upstream 100 bases:

>100_bases
ATAGTGTATGTAAAAAGTGTAGACAATCTTGAAGTAGGAGAATTTGTAAGTGTTCAAATAAATGATGCAATGGAATACGA
TTTAATGGGAGATGTTTTAT

Downstream 100 bases:

>100_bases
AAAATTATGCTTTAATAAATAAAAACTAATGATTAATAAATAAAAAATAACAACTTAAAATTTTAAAAATGTAAAAAAGG
GTATACTATTATAGTATACC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITDALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCM
IEDHLVSSWMVIIIVARELTVSILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
TLYSGWEYLYKNKELFMSSK

Sequences:

>Translated_180_residues
MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITDALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCM
IEDHLVSSWMVIIIVARELTVSILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
TLYSGWEYLYKNKELFMSSK
>Mature_180_residues
MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITDALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCM
IEDHLVSSWMVIIIVARELTVSILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
TLYSGWEYLYKNKELFMSSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=177, Percent_Identity=39.5480225988701, Blast_Score=118, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320059, Length=106, Percent_Identity=40.5660377358491, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20008; Mature: 20008

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITDALDGKIARKYNLVTDF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVSILRAIAAADGKVIAAGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLLTLYSGWEYLYKNKELFMSSK
CCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCHHHHHCCHHHHCCCC
>Mature Secondary Structure
MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITDALDGKIARKYNLVTDF
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVSILRAIAAADGKVIAAGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLLTLYSGWEYLYKNKELFMSSK
CCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA