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The map label for this gene is spoVD [H]

Identifier: 126698825

GI number: 126698825

Start: 1427651

End: 1429315

Strand: Direct

Name: spoVD [H]

Synonym: CD1229

Alternate gene names: 126698825

Gene position: 1427651-1429315 (Clockwise)

Preceding gene: 126698824

Following gene: 126698826

Centisome position: 33.28

GC content: 28.59

Gene sequence:

>1665_bases
ATGTCAAAAAAGAAGACTCCATTTTTGAAAAAAGTGGGAAAGAGAAGCTGGTGTATATTTACTATAATTTTAATAATTTA
TAGTGTTTTAATTTATAGGCTAGTTGATATACAAGTATTAAAAGGTGATAAATACAAACAAAGTGTTGAATCACAAAGCG
TTGAGAAAGTCGAGTTAAATAGTGGAAGAGGAATAATCTATGATAGAAACAACAAGAAGCTTACAGATACAAGTAAATCT
CAGGTATTAATTGTTGAAAAAGAAAAATTAAATAATAACTATAAAATTTTGGAGCTTATTAAGAAAGCTACTAAGATGAA
TGATTTAGATATATATAAAGCTGTACAAGAGCAATTGACACGCCCTATAATACAGATTCAGACTAAAAATATCGATAAGA
GTATGAAAAAAGAACTTGAGAAAAATGGAATAATGGTAGAAGAAAAAACTATGAGGTACGCAAAAGATGGTTTATTATCA
CATACAATAGGATATATAAAAGAAGATGATAAATCAGGTCAATCAGGAATTGAAAAGAGTATGGATAGTGTACTTAGAAA
TTCAAATGAAAAGTATATAAGTGCTTTTAAAGCTGGAGATGCAGGAAATGAAAAATCTCTAAACATACTAAAGGGAAGTG
TAAAAACTGTTGATAATAAGGATAAAGATAGACATCTAAAAACTACTATTGATTATAACATTCAAAAAAAATTAGAACAA
ATACTAAATAAAGAAGAAAATCCTACAGCAGCAATAATCTCGGAAGCATCTACAGGTGAAATTCTTGCAATGTGCTCTAG
ACCTAATTTTGACCAAAATGACATATCAAAAAGTTTAAAAGGAAAAAATGGGGAATTTGAAAATAGAGTTATAAAAGCGA
CATATCCACCAGGGTCTGTATTTAAGATGGTAGTTTTATTTTCTGCACTTGAAAATGGTGTTATAGATGAGAACTATACT
TACAACTGTACAGGTAAGACTAAAGTTGGGAATACTAATGAAATACTGCGATGTAATAAAAGAGATGGTCATGGTTTCCA
AAACTTAAGACAAGCTTTTTCTAATTCATGCAATCCTGCATTTTTAGATATAGCTATGAAACTTGGAAAAGAAAAGATAC
TCAAATCTGCTGAAAAATTACATTTATTTGAAAAGGTTGATATTGGTCTTGATGAAGAAAAAATTAGAGAAGCTCCAAAA
AACATATCAATAAGAAATTTAGCTATAGGTCAAGAAAATATAGAATTTACACCACTTCAAATAAATCAAATGACTCAAAT
AATAGCTAATAATGGAACATTCAAACCACTATACTTATATAAAAGTCTTGTGGACAATAATATGAATACAATAAAAACTT
ATAAGTCTTCAAAAAAAGAAGAACTTATTTCTCCTTATGTGTGTACACAAGTTAAAGAATATATGAAGTCTGTATCTAGG
ATTGGTACAGCTAAAGACCTAAAAGATATTGAAGGTGGTTGTGGAGTTAAAACTGGTACAGCTCAAAGTAGTTTAAATAA
AAAAGCTATAGACCATGGATGGATAACAGGATTTTATCCTGAAGAAAGACCTAAGTATGTAATAACTGTGTTAGTAGAAG
GAACTCAAAAAGGAAATAAATCTGCAACACCTATATTTAAGGAAATATGTGAAAGTATAAAATAA

Upstream 100 bases:

>100_bases
AAGTTATAGAAGAAAAGGTTGAAGAATAATAAAAAATTGATAAAAATAGTATTAGCCCCTTAGAAATTGTCAATAATGAA
ATTATCTAAGGGGTGATTTC

Downstream 100 bases:

>100_bases
ATTATGTACTATAAAATTTAAGGATATATCGTAACTTTGATTTTAGATAGAAAATTTTGTCTAATGATGTACGATATATC
CTTTTAAAATATAGTATTAA

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDKYKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKS
QVLIVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVDNKDKDRHLKTTIDYNIQKKLEQ
ILNKEENPTAAIISEASTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYT
YNCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPK
NISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSR
IGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK

Sequences:

>Translated_554_residues
MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDKYKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKS
QVLIVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVDNKDKDRHLKTTIDYNIQKKLEQ
ILNKEENPTAAIISEASTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYT
YNCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPK
NISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSR
IGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK
>Mature_553_residues
SKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDKYKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQ
VLIVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLSH
TIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVDNKDKDRHLKTTIDYNIQKKLEQI
LNKEENPTAAIISEASTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTY
NCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPKN
ISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSRI
GTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=607, Percent_Identity=24.5469522240527, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786272, Length=569, Percent_Identity=22.3198594024605, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 62619; Mature: 62488

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDKYKQSVESQSVEKVELN
CCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEC
SGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLT
CCCEEEEECCCCEECCCCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
RPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLSHTIGYIKEDDKSGQSGIEKS
CCEEEEECCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVDNKDKDRHLKTTIDYNIQKKLEQ
HHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHCCHHCCCCCCCCCCEEHEECCCHHHHHHH
ILNKEENPTAAIISEASTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSV
HHCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHHH
FKMVVLFSALENGVIDENYTYNCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPA
HHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHEEECCCCCCCHHHHHHHHCCCCCHH
FLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPKNISIRNLAIGQENIEFTPLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCEECCEE
INQMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSR
HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHH
IGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNK
CCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCCCC
SATPIFKEICESIK
CCCHHHHHHHHHCC
>Mature Secondary Structure 
SKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDKYKQSVESQSVEKVELN
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCCEEEEC
SGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKKATKMNDLDIYKAVQEQLT
CCCEEEEECCCCEECCCCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
RPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLSHTIGYIKEDDKSGQSGIEKS
CCEEEEECCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVDNKDKDRHLKTTIDYNIQKKLEQ
HHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHCCHHCCCCCCCCCCEEHEECCCHHHHHHH
ILNKEENPTAAIISEASTGEILAMCSRPNFDQNDISKSLKGKNGEFENRVIKATYPPGSV
HHCCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCHHH
FKMVVLFSALENGVIDENYTYNCTGKTKVGNTNEILRCNKRDGHGFQNLRQAFSNSCNPA
HHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHEEECCCCCCCHHHHHHHHCCCCCHH
FLDIAMKLGKEKILKSAEKLHLFEKVDIGLDEEKIREAPKNISIRNLAIGQENIEFTPLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCEECCEE
INQMTQIIANNGTFKPLYLYKSLVDNNMNTIKTYKSSKKEELISPYVCTQVKEYMKSVSR
HHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHH
IGTAKDLKDIEGGCGVKTGTAQSSLNKKAIDHGWITGFYPEERPKYVITVLVEGTQKGNK
CCCHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCEEEEEEEECCCCCCC
SATPIFKEICESIK
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]