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The map label for this gene is spoIVB [H]

Identifier: 126698809

GI number: 126698809

Start: 1411397

End: 1412455

Strand: Direct

Name: spoIVB [H]

Synonym: CD1213

Alternate gene names: 126698809

Gene position: 1411397-1412455 (Clockwise)

Preceding gene: 126698806

Following gene: 126698810

Centisome position: 32.9

GC content: 26.82

Gene sequence:

>1059_bases
ATGAACAAAATAAATAAAAATTTCAAAAATATTTGGATAATATTAGGAGCTGTATCGATTTTTACCATGGTTATAATTTT
TAATAAAAATTGTAATGTTAATAAAGAGACTCAAATAGAAGCTTTTACAATTAAGAATCATGATAAAAAATTTGTATATC
CTATGGGAAATATAATTGGAGTAAAAGCAAATACAGATGGTGTATTGGTCTTAGGATATGAGGAAGAGGATGTAGACTAT
ATTGGAGGCATACAAATCGGTGATAATATAGTAAAAATAGATAATAAAAGGATAAAAAATAGTCAAGATGTATCAGAGAT
TTTGAATAAGATTAAAAAAAGTAAAGTTGAAGTGACTTTTGAGAGAAAAAATAAGTATAAAACAGAAGTAATAGAGACTA
AAAAAGAAAATGGCAAGTATAAACTTGGATTATGGGTAAGAGATAAAATATCTGGAATTGGAACTATGACTTTTTACGAC
CCTAGTATGGAAAAGTTCAAAGCAATCGGTCATGCCATAAAAGATTCGGATACTAATGAACTATTAAAGATAAAGCAAGG
ATATATATATAAGCCAGAACAATTAAAAATAGTAAAAGCTAGTAATGAAAAAGTAGGTAAAATAAAAGGAGATTTTAATG
ACAGCAATTTAATGGGTAATTTCTCAAATAATTCAGAGCTAGGTATAAGTGGTAATATTACAGAAAACCATAATAAAGAG
TTTAATGTAGCAAATAAAGAAAAGCAATTAATAGAAGTTGGAAGGCCGCAAGATGTAAAAATAGGAGATGCAGTAATTCT
TTTTGAGGATAAAAACAAAAATATAACAAGCTATGATATAAAAATAGAAAGTATAGTATATGATAAAGGAAATTATAGAG
ATATGGTAATAAAAGTAGTAGATGACAAGTTATTGGAATACACAGGAGGTATCGTACAGGGGATGAGTGGAGCTCCAATA
ATACAAAATAATAAAATTATTGGTGCAATAACTCATGTTTTTAGAGATAATCCGAAAAAAGGATATGGTATTTTTATAGA
TGAAATGATAAAATTGTAG

Upstream 100 bases:

>100_bases
ATCACTTATTAAGATTTTAAATAAACTTTTTAAATGAATAAATTCTCAGGAAAAAGGAATTATAAATACATAATAATACA
GCATAGGAGTAGATGGATAT

Downstream 100 bases:

>100_bases
GTGAGGCATTAAAAAATTTTATTATTTTATCAATTATCTAGGAGGAATATAATTTTGGAGTGTCGAATATGCTTTAGAGT
AGATAATTAGGAAGCAATTG

Product: stage IV sporulation protein B

Products: NA

Alternate protein names: Sporulation factor IV B protease; Stage IV sporulation protein B [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTIKNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDY
IGGIQIGDNIVKIDNKRIKNSQDVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLMGNFSNNSELGISGNITENHNKE
FNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNITSYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPI
IQNNKIIGAITHVFRDNPKKGYGIFIDEMIKL

Sequences:

>Translated_352_residues
MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTIKNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDY
IGGIQIGDNIVKIDNKRIKNSQDVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLMGNFSNNSELGISGNITENHNKE
FNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNITSYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPI
IQNNKIIGAITHVFRDNPKKGYGIFIDEMIKL
>Mature_352_residues
MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTIKNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDY
IGGIQIGDNIVKIDNKRIKNSQDVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLMGNFSNNSELGISGNITENHNKE
FNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNITSYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPI
IQNNKIIGAITHVFRDNPKKGYGIFIDEMIKL

Specific function: Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by c

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Forespore intermembrane space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase S55 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR014219
- InterPro:   IPR008763 [H]

Pfam domain/function: PF00595 PDZ; PF05580 Peptidase_S55 [H]

EC number: =3.4.21.116 [H]

Molecular weight: Translated: 39892; Mature: 39892

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTIKNHDKKFVYPMGNIIG
CCCCCCCCCEEEEEEEHHHHEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEECCCEEE
VKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQDVSEILNKIKKSKVEVTF
EEECCCCEEEEEECCCCCCEECCEEECCEEEEECCCCCCCHHHHHHHHHHHHHCEEEEEE
ERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYDPSMEKFKAIGHAIKDSDTNE
ECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCCHH
LLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLMGNFSNNSELGISGNITENHNKE
HHEECCCCEECCCEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCCCEECCCCCCCCCC
FNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNITSYDIKIESIVYDKGNYRDMVIKVV
CCCCCCHHHHHHCCCCCCEEECCEEEEEECCCCCEEEEEEEEEEEEECCCCCCEEEEEEH
DDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVFRDNPKKGYGIFIDEMIKL
HHHHHHHCCHHHCCCCCCCEEECCEEEEEEHHHHHCCCCCCCCEEHHHHHCC
>Mature Secondary Structure
MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTIKNHDKKFVYPMGNIIG
CCCCCCCCCEEEEEEEHHHHEEEEEEECCCCCCCCCCEEEEEEEECCCCEEEEECCCEEE
VKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQDVSEILNKIKKSKVEVTF
EEECCCCEEEEEECCCCCCEECCEEECCEEEEECCCCCCCHHHHHHHHHHHHHCEEEEEE
ERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYDPSMEKFKAIGHAIKDSDTNE
ECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCCHH
LLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLMGNFSNNSELGISGNITENHNKE
HHEECCCCEECCCEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCCCEECCCCCCCCCC
FNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNITSYDIKIESIVYDKGNYRDMVIKVV
CCCCCCHHHHHHCCCCCCEEECCEEEEEECCCCCEEEEEEEEEEEEECCCCCCEEEEEEH
DDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVFRDNPKKGYGIFIDEMIKL
HHHHHHHCCHHHCCCCCCCEEECCEEEEEEHHHHHCCCCCCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2106508; 8969508; 9384377; 11741860 [H]