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The map label for this gene is xseA

Identifier: 126698799

GI number: 126698799

Start: 1401749

End: 1402954

Strand: Direct

Name: xseA

Synonym: CD1203

Alternate gene names: 126698799

Gene position: 1401749-1402954 (Clockwise)

Preceding gene: 126698798

Following gene: 126698800

Centisome position: 32.67

GC content: 27.36

Gene sequence:

>1206_bases
ATGAAACTAAGAGCTTTAGATATAAGTGAAGCAAACTCATATATTAAAAGAATTTTAATAAACGACCCAATACTTTCTAA
TCTTAAAGTTAAAGGAGAAATTTCTAATTTTAAGGTTCATAGTAGTGGGAATGTATATTTATCACTTAAAGATGAAACAT
CAAAGTTAAACTGTGTAATTTTTAAAAGTAATTTTAATCGCAATTTAAAATTAGATAATGGTGTAAAAATTATAGCTAAT
GGATATATATCAGTCTATGAAAGAGATGGTGCGTATCAATTATACATTAATGAAATTGAAATAGAGGGAATAGGAAATTT
ACACATAGAGTTTAATAGATTAAAGGAAAAACTTAATAAAGAAGGATTATTTGACCCTAAATACAAGATACCTATACCTA
AAATGCCAAACTCAATTGGCGTTATAACATCTCCAACAGGTGCTGTTATAAGAGATATAATAAATGTAATAAAAAGAAGA
TATCCGAAAGTTAATATAAAGCTTTATCCAGTAACGGTTCAAGGAGATAAATCAGCTGAAGAAATCTGTGAAGCAATTAG
ATTTTTCAATCATATGAAGAATGTTGATACACTTATAGTTGGTAGAGGTGGGGGTTCAATAGAAGAACTTTGGTCTTTTA
ATGATGAAATGGTAGCAAGAGAGGTTTTTAATTCTCAAATTCCGATAATATCAGCAGTTGGGCATGAAACGGATTTTACT
ATTTGTGATTTTGTGTCTGATATGAGAGCCCCAACGCCATCAGCAGCAGCTGAGATTGCTACTCCATCATTGGATGATAT
AAACTATAAACTTGGAAACATAAAAAGTAGGATGAGTAAGTCTCTTACAAATCAAATAGAGCTAGACCAATATAGGTTAG
AAACAGTATTTAATAAGATAAATAACTATTTAGATTCGTACACAATAAAAGATAAAGTTATACAATTAGACAAAATATAT
GATAAAATAATTTTTGGAATAGAAAATAATTTAAAATTAGAAGATGAAAAATTAGTAAAAATTGGAGCATTACTCCATAA
TTTAAGTCCATTAGCTACTATGGATAGAGGTTATAGTATAACTCAAAAAAATGGAAAAGTAATAAATAGTATAAAAGGAT
TAAAAATAAAGGATAGTATAGATATAGTATTAAAAGATGGAAATTTAGAATGTATGATAGATAAAATTGAAAATAAAGAG
GGATAG

Upstream 100 bases:

>100_bases
AAAAGCATATAGAAGCTTATTTTACAGAACCACAATATTCAACTGATAATGCTGTCGGGTGTGCTATAATAGGATTGAAT
AACTTTTTAGGAGAAAGAGT

Downstream 100 bases:

>100_bases
TATGAATTTAACCTACGAAGAAGCTTATAAAAGATTAGAAAGTATTTTAAGTGAATTAGAATCTAAAAATGCTAGCTTGG
ATGAATCTTTAAGCCTATAT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGNVYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIAN
GYISVYERDGAYQLYINEIEIEGIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMVAREVFNSQIPIISAVGHETDFT
ICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKSRMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIY
DKIIFGIENNLKLEDEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECMIDKIENKE
G

Sequences:

>Translated_401_residues
MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGNVYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIAN
GYISVYERDGAYQLYINEIEIEGIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMVAREVFNSQIPIISAVGHETDFT
ICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKSRMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIY
DKIIFGIENNLKLEDEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECMIDKIENKE
G
>Mature_401_residues
MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGNVYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIAN
GYISVYERDGAYQLYINEIEIEGIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMVAREVFNSQIPIISAVGHETDFT
ICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKSRMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIY
DKIIFGIENNLKLEDEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECMIDKIENKE
G

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=33.4096109839817, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_CLOD6 (Q18B66)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087696.1
- STRING:   Q18B66
- GeneID:   4913263
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1203
- NMPDR:   fig|1496.1.peg.192
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   FPALMQG
- ProtClustDB:   CLSK2534737
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 45300; Mature: 45300

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGNVYLSLKDETSKLNCVI
CCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECEEEEECCCCEEEEEECCCCEEEEEE
FKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIEGIGNLHIEFNRLKEKLNK
EECCCCCCEEECCCEEEEEECEEEEEEECCEEEEEEEEEEEECCCEEEEEHHHHHHHHCC
EGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRRYPKVNIKLYPVTVQGDKSAE
CCCCCCCEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCHH
EICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMVAREVFNSQIPIISAVGHETDFT
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCCH
ICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKSRMSKSLTNQIELDQYRLETVFNKI
HHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
NNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLEDEKLVKIGALLHNLSPLATMDRGYSI
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCHHHHCCCCEE
TQKNGKVINSIKGLKIKDSIDIVLKDGNLECMIDKIENKEG
ECCCCCEEHHCCCCEEECCEEEEEECCCEEEEEEECCCCCC
>Mature Secondary Structure
MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGNVYLSLKDETSKLNCVI
CCEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECEEEEECCCCEEEEEECCCCEEEEEE
FKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIEGIGNLHIEFNRLKEKLNK
EECCCCCCEEECCCEEEEEECEEEEEEECCEEEEEEEEEEEECCCEEEEEHHHHHHHHCC
EGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRRYPKVNIKLYPVTVQGDKSAE
CCCCCCCEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCHH
EICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMVAREVFNSQIPIISAVGHETDFT
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCCH
ICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKSRMSKSLTNQIELDQYRLETVFNKI
HHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
NNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLEDEKLVKIGALLHNLSPLATMDRGYSI
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCHHHHCCCCEE
TQKNGKVINSIKGLKIKDSIDIVLKDGNLECMIDKIENKEG
ECCCCCEEHHCCCCEEECCEEEEEECCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA