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The map label for this gene is ackA

Identifier: 126698770

GI number: 126698770

Start: 1375461

End: 1376657

Strand: Direct

Name: ackA

Synonym: CD1175

Alternate gene names: 126698770

Gene position: 1375461-1376657 (Clockwise)

Preceding gene: 126698768

Following gene: 126698771

Centisome position: 32.06

GC content: 32.41

Gene sequence:

>1197_bases
ATGAAAATATTAGTATTAAACTGTGGGAGTTCTTCATTAAAATATCAATTAATAGATATGAATAATGAAGAAGTTTTATG
TATAGGATTGGTTGAAAGAATAGGAATAGAAGGTTCTATATTAAAACATGAAAAAGCAGGTAGAGATGATAAATACGTTG
TTGAACAACCAATGAAGGACCACAAAGATGCAATAGCATTAGTTTTAGAAGCTGTTGCTCATCCAGAATTTGGTGCAGTT
AAAGAAATGAAAGAAATAGATGCAGTAGGACATAGAGTTGTACATGCTGGAGAAAAATTTGCAACTTCAGTAGTAATAAC
TCCAGAAGTAGAAGAAGCTTTAAAAGAATGTATAGATTTAGCTCCACTTCATAATCCAGCAAACATAATGGGAATAGATG
CTTGTAAAGCTATACTTCCAGATGTACCAATGGTAGGTGTATTTGATACTGCTTTCCATCAAACAATGCCTAAATCTTCA
TACTTATATGGTTTACCTCATGAGCTATATACTAAATATGGGGTAAGAAGATATGGATTCCACGGAACTTCTCATAATTA
TGTATCTCAAAGAGCAGCAGAGATATTAGGAAAAGATATAAAAGATTTAAAAATAGTAACTTGTCACTTAGGAAATGGTG
CTTCTATAGCTGCTGTTGATGGTGGAAAATGTGTAGATACATCTATGGGATTCACTCCATTAGAAGGATTAATAATGGGA
ACTAGATGTGGAGATATAGACCCAGCTATATTACCATTCTTAATGAGAAAAGAAGGTTTAGATGCTGATGGATTGGATAA
ATTAATGAATAAAGAATCTGGAGTATATGGAATGACTGGAATTTCTAGTGACTTCAGAGATATAGAAGATGCAGCTAAAA
ATGGAGACGAAAGAGCTCAAGCTACATTAGAAGCGTATGTTAAAAAAGTACAAAAATATATAGGCGCTTATGCTGCTGAA
ATGAATGGATTGGATGTTGTAGTATTTACTGCAGGCGTTGGTGAAAATGGAAAGGCTATAAGAGCAGATATTGCTTCTAA
CATGGAGTTTTTAGGAATGAAATTAGATAAAGAAGCTAATGATGTTAGAGGAAAAGAAACAGTAATATCTACTGCTGATT
CTAAAGTAAAAATGCTTTTAATACCAACTAATGAAGAATTAATGATAGCTAGAGATACATTAAGATTGGTAAAATAA

Upstream 100 bases:

>100_bases
CTATAACAAAATAATAAAAGATAGAGTTTTATTTAGACATTTATTACAAATCAAAATTTATTACATATTATTTATAAAAA
AATCTAAGGAGGAAATAATA

Downstream 100 bases:

>100_bases
TTAAATTAAACCTATGCCTATCAAGTAAAAATACTTGACAAACAAATGCTAGATTTGTATAATAAATTTGGTGATATGTT
GAGGTGAACTTAATGAAAGT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAV
KEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMG
TRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAE
MNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK

Sequences:

>Translated_398_residues
MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAV
KEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMG
TRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAE
MNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK
>Mature_398_residues
MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAV
KEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMG
TRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAE
MNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI1788633, Length=402, Percent_Identity=45.5223880597015, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=41.8546365914787, Blast_Score=322, Evalue=3e-89,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ACKA_CLOD6 (Q18B36)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087667.1
- ProteinModelPortal:   Q18B36
- SMR:   Q18B36
- STRING:   Q18B36
- GeneID:   4916377
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1175
- NMPDR:   fig|1496.1.peg.221
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   TDEEYMI
- ProtClustDB:   CLSK2534720
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43321; Mature: 43321

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKD
CEEEEEECCCCCEEEEEEECCCCCEEEEEEHHHHCCCCCEECHHHCCCCCCHHHHCCHHH
HKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHH
APLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSSYLYGLPHELYTKYGVRRYGF
CCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEECCCHHHHHHHCCHHCCC
HGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMG
CCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCEEEE
TRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQ
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCHHHHH
ATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEAN
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHHCCHHHCCEECCCCCH
DVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK
HCCCCHHEEECCCCCEEEEEEECCCCEEEEHHHHHHCC
>Mature Secondary Structure
MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHEKAGRDDKYVVEQPMKD
CEEEEEECCCCCEEEEEEECCCCCEEEEEEHHHHCCCCCEECHHHCCCCCCHHHHCCHHH
HKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFATSVVITPEVEEALKECIDL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHH
APLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSSYLYGLPHELYTKYGVRRYGF
CCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEECCCHHHHHHHCCHHCCC
HGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAAVDGGKCVDTSMGFTPLEGLIMG
CCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCEEEE
TRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVYGMTGISSDFRDIEDAAKNGDERAQ
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCHHHHH
ATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVGENGKAIRADIASNMEFLGMKLDKEAN
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEHHHHCCHHHCCEECCCCCH
DVRGKETVISTADSKVKMLLIPTNEELMIARDTLRLVK
HCCCCHHEEECCCCCEEEEEEECCCCEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA