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The map label for this gene is coaE [H]

Identifier: 126698723

GI number: 126698723

Start: 1329231

End: 1329833

Strand: Direct

Name: coaE [H]

Synonym: CD1129

Alternate gene names: 126698723

Gene position: 1329231-1329833 (Clockwise)

Preceding gene: 126698722

Following gene: 126698724

Centisome position: 30.98

GC content: 30.68

Gene sequence:

>603_bases
ATGTTGATATTAGGACTTACAGGAGGAATAGGCTGTGGAAAAAGCAGCCTATCAAATATATTTAGAAATCTTAACATTCC
TATAGTGGATGCTGATATTATATCCAGGAAGATATTTGAGGATAAGTTGTTATTGGAAAAAGTATTTGTCCATTTTGGGC
AAAGTATAAAAAATGATGATGGAACTCTAAATAGAAAAGCTCTTGGGAAAATAGTTTTTAGTGATGAAGAAAAACTTAAG
GAATTAAATAACTTGACTCATCCACGAATAAGAGAAAAAATAATAAGTGAAATAGAAAAATTGAGAAAAAAAGGCGAAAA
TATAGTAGTGTTAGATGCGGCAATATTGGTAGAAAGTGGTTTTTTAGATATGGTTGACAAGCTATTAGTAGTTACTTGTA
AACAAGAAGTACAAATTAGCAGAATACAAAAGAGAGATAATTGCAGTGAGCAGGAAGCACTTAGTAGGATAAATTCACAG
ATGAGTCAGGAAGAAAAATCCAAATATGGTGATTATATAATAGATAATTCGGGAACAATAACTGAATTAGAAAGTAAAGC
ACATAAATTTATTGAGTACATGAAGGAGAATTGGCGTGAATAG

Upstream 100 bases:

>100_bases
TAGTAAAAGAAGAAATGGAAAATGCTGTAAATATGGATGTTCACTTAGATGTAGATTTAAATGTAGGTAGTTCTTGGTAT
GAGACAAAGTAGGTGATTTT

Downstream 100 bases:

>100_bases
TAAGAAAGTATTGATTCTATCTATTTTTATAATCTTATTTGGGGCACTATTAATGGAAAGCAAAGTAATACATAAATTTT
TATATCCTAAAAAATATTCA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLLLEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLK
ELNNLTHPRIREKIISEIEKLRKKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE

Sequences:

>Translated_200_residues
MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLLLEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLK
ELNNLTHPRIREKIISEIEKLRKKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE
>Mature_200_residues
MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLLLEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLK
ELNNLTHPRIREKIISEIEKLRKKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=32.2222222222222, Blast_Score=123, Evalue=8e-29,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=32.2222222222222, Blast_Score=123, Evalue=8e-29,
Organism=Homo sapiens, GI110227607, Length=166, Percent_Identity=31.9277108433735, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=31.9277108433735, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI110227605, Length=166, Percent_Identity=31.9277108433735, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI110227603, Length=166, Percent_Identity=31.9277108433735, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI110227601, Length=166, Percent_Identity=31.9277108433735, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI1786292, Length=184, Percent_Identity=33.1521739130435, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17554944, Length=203, Percent_Identity=37.4384236453202, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143409, Length=166, Percent_Identity=34.9397590361446, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320402, Length=189, Percent_Identity=42.3280423280423, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24644728, Length=203, Percent_Identity=37.4384236453202, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24658602, Length=166, Percent_Identity=31.9277108433735, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22828; Mature: 22828

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLLLEKVFVHFGQSIKNDD
CEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLRKKGENIVVLDAAILVESG
CCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCC
FLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQMSQEEKSKYGDYIIDNSGTI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
TELESKAHKFIEYMKENWRE
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLLLEKVFVHFGQSIKNDD
CEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLRKKGENIVVLDAAILVESG
CCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCC
FLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQMSQEEKSKYGDYIIDNSGTI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
TELESKAHKFIEYMKENWRE
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]