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The map label for this gene is zupT [H]

Identifier: 126698674

GI number: 126698674

Start: 1280584

End: 1281387

Strand: Direct

Name: zupT [H]

Synonym: CD1087

Alternate gene names: 126698674

Gene position: 1280584-1281387 (Clockwise)

Preceding gene: 126698673

Following gene: 126698675

Centisome position: 29.85

GC content: 30.22

Gene sequence:

>804_bases
TTGAATAATGTAATATTTGCATTTTTGATAACATTATTGGCTGGTTTATCTACTGGTATAGGAAGTTGTATAGCATTTTT
TGCTAAAAAAACAAATACTAAGTTTCTTTCTATAAGCTTAGGATTTTCTGCTGGTGTTATGATTTATGTTTCTATGATAG
AAATTTTTCCTAAAGCACAAGATGCTTTGACAAAATCTATGGGAGAGAAATTAGGAAGTTGGTCAACTGTAATAGCTTTT
TTTATAGGTATGGCTATCATTGCTGCTATTGATAAGCTAATTCCACAAGAAGAAAATCCACATGAAATAAAGAAAATGGA
GAATATAGAAGAAAAGAATATCAAAAAAAATAAGTCTCTTTTAAGAACAGGTATATTTACAGCAATGGCTATAGCAATTC
ACAATTTTCCTGAAGGATTAGCTACATTTATATCAGCTCTTGATGATGTTACAATAGCTATTCCGATAGCAATTGCAATT
GCAATACACAATATACCAGAAGGTATATCTGTATCTGTACCAGTTTATTATGCCACAGGAGATAAAAAGAAAGCTTTTTA
TTATTCCTTTTTATCTGGTATGTCTGAGCCTTTAGGAGCGATTATTGGATATGTACTTCTTAGAAATTTTTTAAATGATA
TAACTCTTGGAATTGTATTTGCAATTGTAGGAGGAATTATGGTATTCATATCACTAGATGAATTATTGCCATCAGCTAGA
GAGTACGGGGAACATCATTTATCTATTTATGGATTGATTGCAGGAATGGGTGTTATGGCTATTAGTTTATTACTATTTAA
ATAG

Upstream 100 bases:

>100_bases
TTTTATTATGTATATTTTTTATAAATATTGACTATATAAAATATATATGATAGCATAAAGAAAATGATAATCAATATCAA
TTAAAAAGAAGGTGATTTAT

Downstream 100 bases:

>100_bases
CTTTTAAATATATGATTGTAACCTAAAATTAGTATCAAAATGATATAATTATTTAAATAGATTTTTAAGCTATTTAAAAA
TATCATTTTGGAGAATGAGT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSAGVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAF
FIGMAIIAAIDKLIPQEENPHEIKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGIVFAIVGGIMVFISLDELLPSAR
EYGEHHLSIYGLIAGMGVMAISLLLFK

Sequences:

>Translated_267_residues
MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSAGVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAF
FIGMAIIAAIDKLIPQEENPHEIKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGIVFAIVGGIMVFISLDELLPSAR
EYGEHHLSIYGLIAGMGVMAISLLLFK
>Mature_267_residues
MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSAGVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAF
FIGMAIIAAIDKLIPQEENPHEIKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGIVFAIVGGIMVFISLDELLPSAR
EYGEHHLSIYGLIAGMGVMAISLLLFK

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=324, Percent_Identity=27.1604938271605, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI229577422, Length=331, Percent_Identity=26.2839879154079, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1789419, Length=261, Percent_Identity=35.2490421455939, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17507805, Length=302, Percent_Identity=25.8278145695364, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24652846, Length=170, Percent_Identity=31.7647058823529, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28924; Mature: 28924

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSAGVMIYVSMIEIFPKAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCHH
DALTKSMGEKLGSWSTVIAFFIGMAIIAAIDKLIPQEENPHEIKKMENIEEKNIKKNKSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHH
LRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAIAIHNIPEGISVSVPVYYATG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECC
DKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGIVFAIVGGIMVFISLDELLPSAR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYGEHHLSIYGLIAGMGVMAISLLLFK
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSAGVMIYVSMIEIFPKAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCHH
DALTKSMGEKLGSWSTVIAFFIGMAIIAAIDKLIPQEENPHEIKKMENIEEKNIKKNKSL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHH
LRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAIAIHNIPEGISVSVPVYYATG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECC
DKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGIVFAIVGGIMVFISLDELLPSAR
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYGEHHLSIYGLIAGMGVMAISLLLFK
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]