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The map label for this gene is hydA [H]

Identifier: 126698471

GI number: 126698471

Start: 1076412

End: 1077908

Strand: Direct

Name: hydA [H]

Synonym: CD0894

Alternate gene names: 126698471

Gene position: 1076412-1077908 (Clockwise)

Preceding gene: 126698470

Following gene: 126698472

Centisome position: 25.09

GC content: 31.13

Gene sequence:

>1497_bases
ATGTTTGAATTTGAAACGCAACTAAAAAGGTTAAAACATGAAGTTTTAACAGCAGTAGCAAGACTATCTATTGAAGAAAA
TTTAACAAAAGAAAATATAGAAAAAATTCCATATGAAATAATTAAAGGAGAAAAGGCGAGATATAGATGTTGTGTTTATA
AAGAGAGAGAAGTAGTTCTTGAAAGGGCGCAACTTGCATTAAGTTTAACTCCAAATAGTAAATATGGAGATATAAATCCA
GATTCAGTTAGTTTGGACACAGATGAGCAAATTATATATATAGTTGAAGCAGCATGTGATAGATGTCCAATAAATGAATT
TACAGTTACAGAGCTTTGTAGAGGGTGTTTGGCTCATAGATGTAAGGAAGCATGTAAATTTGGGGCAATTTCTTATATAA
ATGGGAGAGCATATATAAATCATGATTTATGTAAGGCTTGTGGAATGTGCAAAAGTTCATGTCAATATGATGCTATATCA
GAAGTTGTAAGACCTTGTAAAAGCGTTTGTCCAACAGGAGCTTTGGATTTTAATAGAAACACTATGAAAGCAATGATACA
TGAAGATAATTGTATAAATTGTGGAGCATGTATGTCAGCATGTCCTTTTGGAGCAATATCTGATAAGAGTTTGATAGCAC
CTGTTGCAAAAAAACTTGCAAAGAAAGAAAATATGTATGCAATAGTAGCTCCAGCTATAACAGGTCAAATAGATAGTAAT
ATTACATATGGTCAGTTAAAAAATGCTATAAAATCACTGGGATTTGTAGATATGATAGAAGCTTCTTGTGGAGCAGATGC
AGTTACAGTTCATGAAAGCAATGAACTTATTGAAAGAATAAAATCAGGAGATAATTACATGACAAATTCATGTTGTCCGG
GATTTTTTAAGTATATAGAGAAGATGTTCCCAGATGAAAAAGATAGAATATCATCTACAGTGTCTCCTATGGTAGCAACA
GGAAGATTAGTAAAAAAAATAGATTCTGATGCTAAAGTTGTATTTATAGGTCCATGTACAGCTAAAAAGAGTGAGGCAAC
AGAGAAAAGTTTAAAAGATTCAGTAGATTATGTACTTACTTTTGAAGAACTAATGGCATTATTTGAAGCATTTAATATAG
ATTTATCAAAATGTTCAAATGAAGATATAAATGATGGTTCGATTTTTGGAAGGGGATTTGGAGCATCTGGTGGACTTGCC
AAATCAGTACAGAACTATATTGCTGAAAAGGGGCTTAGTTTTGATTTTGAACCTATAAAAGTATCTGGTCCAAGACAAAT
TAAAAAGACAATGACAATGGCTAAATTGGGAAGATTAGAAGGTAATTTTATAGAAGGAATGATGTGTGAAGAAGGTTGTA
TTAATGGAGCAGGTAAGTTTTTATCAGGTGTAAAAGCTAAAAATACTTTTGATAGAAAAAATGGACAATCTACTAAAAAG
AGTGTTTTATCTAATGATAAGATTAAAGAATTTGAAGATGTAAATTTAGAAAGATAA

Upstream 100 bases:

>100_bases
TATGCCTATGTTATAATAATTTATAGAAATAAATAAAAAATACAATATACATAATAGTAGAAATATAGCAAAAAGGTGTG
ATTTATAGGGAGGATTACTT

Downstream 100 bases:

>100_bases
TTGTTTTGGTACAGTCATTTTTTTATCATGTTTTTATCATGCCACAAATATGCCTAAAATTTGCCCTTTTTATATGTGTA
TTTTACAGAGTTAAGGTTGC

Product: iron-dependent hydrogenase

Products: NA

Alternate protein names: Fe hydrogenlyase [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVLERAQLALSLTPNSKYGDINP
DSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSN
ITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVAT
GRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLA
KSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKK
SVLSNDKIKEFEDVNLER

Sequences:

>Translated_498_residues
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVLERAQLALSLTPNSKYGDINP
DSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSN
ITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVAT
GRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLA
KSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKK
SVLSNDKIKEFEDVNLER
>Mature_498_residues
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVLERAQLALSLTPNSKYGDINP
DSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSN
ITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVAT
GRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLA
KSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKK
SVLSNDKIKEFEDVNLER

Specific function: May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme [H]

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR013352 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF00037 Fer4 [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 54995; Mature: 54995

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCEEEEEEHHHHHHH
ERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHR
HHHHEEEEECCCCCCCCCCCCCEECCCCCCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHH
CKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAISEVVRPCKSVCPTGALDFNRN
HHHHHHCCCEEEECCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSN
HHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCC
ITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIE
CCHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHH
KMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLT
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
FEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLAKSVQNYIAEKGLSFDFEPIK
HHHHHHHHHHHCCCHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEE
VSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKK
ECCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHH
SVLSNDKIKEFEDVNLER
HHHCCCCHHHHCCCCCCC
>Mature Secondary Structure
MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGEKARYRCCVYKEREVVL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCEEEEEEHHHHHHH
ERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRCPINEFTVTELCRGCLAHR
HHHHEEEEECCCCCCCCCCCCCEECCCCCCEEEEEEHHHCCCCCCCCCHHHHHHHHHHHH
CKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAISEVVRPCKSVCPTGALDFNRN
HHHHHHCCCEEEECCCEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
TMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKKLAKKENMYAIVAPAITGQIDSN
HHHHHCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCC
ITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNELIERIKSGDNYMTNSCCPGFFKYIE
CCHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHH
KMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVVFIGPCTAKKSEATEKSLKDSVDYVLT
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
FEELMALFEAFNIDLSKCSNEDINDGSIFGRGFGASGGLAKSVQNYIAEKGLSFDFEPIK
HHHHHHHHHHHCCCHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCEE
VSGPRQIKKTMTMAKLGRLEGNFIEGMMCEEGCINGAGKFLSGVKAKNTFDRKNGQSTKK
ECCHHHHHHHHHHHHHHCCCCCHHCCCHHHHHCCCCHHHHHHCCCCCCCCCCCCCCHHHH
SVLSNDKIKEFEDVNLER
HHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2661538 [H]