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The map label for this gene is speB [H]

Identifier: 126698468

GI number: 126698468

Start: 1072917

End: 1073795

Strand: Direct

Name: speB [H]

Synonym: CD0891

Alternate gene names: 126698468

Gene position: 1072917-1073795 (Clockwise)

Preceding gene: 126698467

Following gene: 126698470

Centisome position: 25.01

GC content: 29.81

Gene sequence:

>879_bases
ATGAAGAATAATTTCTATCATATGAACACTTTTATGAGTATGGACAAAAATTATGAAGAATCTAATCTTATAGTATTTGG
TGTTGGATTTGATGGAACTACTTCTAACAGACCTGGGGCTAGATTTGCAAGTAGCTCTATGAGAAAAGAATTTTACGGTC
TTGAGACATACAGTCCTTTTTTAGATTTGGATTTAGAGGATTATAATATATGTGATTATGGAGATTTAGAAATTAGTGTT
GGAAGTACAGAACAAGTCTTAAAAGAAATCTATCAAGAGACATATAAGATTGTTAGAGATTCAAAGGTACCCTTTATGAT
TGGAGGAGAGCATTTAGTTACATTACCAGCCTTTAAAGCAGTACATGAAAAGTACAATGATATATATGTAATTCATTTTG
ATGCCCATACTGATTTGAGGGAAGAATATAATAATAGTAAAAATTCTCATGCAACAGTAATTAAAAGAATATGGGATATT
GTAGGTGATAATAAAATATTTCAATTTGGTATAAGGTCTGGGACAAAAGAAGAATTTAAATTTGCTACAGAAGAAAAACA
CACATACATGGAAATAGGAGGAATAGATACATTTGAAAATATAGTTAACATGCTAAATGGAAAGAATATTTATCTAACTA
TAGATTTAGATGTATTGGATGCATCTGTGTTTCCAGGAACAGGTACACCAGAACCTGGTGGTGTAAATTATAGAGAGTTT
CAAGAGATTTTTAAGATTATAAAAAACTCTAATATAAATATAGTTGGTTGTGACATTGTAGAGTTAAGCCCTGATTACGA
TACAACAGGTGTATCGACAGTTATAGCTTGTAAAATCCTAAGAGAGTTATGCTTAATAATATCTGATAAAATTAAATAG

Upstream 100 bases:

>100_bases
AGAAATGGATGGGAGAAATTAAGTTTAAAAACTAAATATTATAATAGTGATATACATTTAGGTTCGTTTATGTTACCTCA
ATATGTGAAGGAGATGCTAG

Downstream 100 bases:

>100_bases
AGTATTTTATATAAATAGTATATATTATAATATAAGAAGTTATTTTAAAAAAGTTAGTTTAAGTTTGACGCTTTTCTAAA
GTAACTTCTTATTTTTGTAA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISV
GSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREF
QEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK

Sequences:

>Translated_292_residues
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISV
GSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREF
QEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK
>Mature_292_residues
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISV
GSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREF
QEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=289, Percent_Identity=29.0657439446367, Blast_Score=145, Evalue=3e-35,
Organism=Escherichia coli, GI1789306, Length=289, Percent_Identity=27.3356401384083, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33308; Mature: 33308

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPF
CCCCEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
LDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKA
EECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEHHHHHH
VHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDIVGDNKIFQFGIRSGTKEEFK
HHHHCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
FATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREF
HHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEEEEEEECEECCCCCCCCCCCCCHHHH
QEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK
HHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPF
CCCCEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
LDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKA
EECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEHHHHHH
VHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDIVGDNKIFQFGIRSGTKEEFK
HHHHCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHH
FATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREF
HHCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEEEEEEEECEECCCCCCCCCCCCCHHHH
QEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIK
HHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]