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The map label for this gene is speA [H]

Identifier: 126698465

GI number: 126698465

Start: 1070071

End: 1071546

Strand: Direct

Name: speA [H]

Synonym: CD0888

Alternate gene names: 126698465

Gene position: 1070071-1071546 (Clockwise)

Preceding gene: 126698464

Following gene: 126698466

Centisome position: 24.94

GC content: 29.47

Gene sequence:

>1476_bases
ATGGATAGCGAGTTTGCAAATGCAGTTGAATTAAGCTATGAGTGTGCTCCATTATTAGAGTCGTTAAAGGAATACTCAGA
GAAAGATATAGCTTGTTTTGATGTGCCTGGACATGTAAAAAATAGAGGTGTAGCTATATTAAATAAATATCTAGGTGAAA
GTCTCATGAAAATGGATATAAATTCATCACCAACTATGGATAATGTATCTGCGCCAAATGGGATTATAAAAAATGCACAA
GATTTGCTAGCACAAGCATATATGGCTGATGAGGCATTCTTTATAACGAATGGCACAACTCAAGCAATACATGCAATGAT
TTTGAGTGTTATAAAACCAGGTGAAAAAGTATTACTTCCAAGAAATATACATAAATCAGTAATAAATGCGTTAATACTTT
GTGGAGGAATACCAATATTTATACAACCAGAATTTGATGAAAAACTAGGTATAAGTTTAAATATTACTCTTGAAAAAGTT
AGAACAGAGATAGAAAAAGATTGTAATATAAAAGCATTATTTTTCCTTAATCCAACTTACTATGGAGTTTGTGCAGACCT
TGAGAGTATTATAGAACTATGCCATAAAAATAATGTTTTAGTGTTAGTTGATGAAGCTCATGGTGCACATTTTCCATTTC
ATTTAGATTTACCTCCTTCTGCAATAAGTTTGGGAGCTGATATGGTAGCTGTAAGTATACATAAAACTGGAGGAGCATTG
ACACAATCTTCAGCACTCTTATTGAATAGAGATAATGTAAGTTTTGAAAAGGTTCTTCAATCAATCAATATGCTACAATC
AACATCAGCATCTTATTTGCTTATGGCAAGTATAGATGGTGCTAGAGTTAATCTAGTTGAGAATGGTGAAAAGCAATTGT
CAAAAGCATTAAATCTATCTAGGTATGCAAAATCTAAATTGAACAAAATTGATGGAATAAAAGTTTTATCTACAGAAATA
TTGAAACAAAAAGGTGTTAAATTTATAGATGAAACAAAATTGTGTATAAATGTAAAAGAATTAAATTTGACTGGATTTGA
AGTATACGATTTATTATATAAAAATTTTTCAATTCAAGTAGAATTGGGAGATTCATATAATATACTGGCACTTGTGTCCA
TTGGAACAAATAAATCAGATATAGATAGATTAGTAAAAGCACTTTCTATAATTGCAAAGGTTTATAGAAAAGAATCAACA
TTAAATGAATTTAATATGGTTCAAATAAATCCAATTATTAAACTTAATCCAAGAGAAGCTTTTTATGCACCAAAGGAAAG
TGTAGAAATCAATTCATGTATAGATAGAATTTGTGGAGAATCAATAATGGCATATCCACCAGGTATACCGATTATTGCTC
CAGGAGAATTGATAACAGAAGAAATTATGGAGTATATTATTTTCTTAAAAAATAGCAATGCGTATCTTACAGATGTACAA
GATAAAAACTTAGATAGAATACTAGTAATAAAATAA

Upstream 100 bases:

>100_bases
TAAATATCATGAGTTTAATAAAAGTAAAAATAAAAAATAGAAATAATAAATAATAAATATTAAAAATATTTGAATATAGA
GAGGAGATGAATTTGAAATC

Downstream 100 bases:

>100_bases
ATTACTTTATTTTGCAAGGGCAAGTGTTTGTTAAGTAGAGTTTATCAAATAGAACTTATTAAAAGTATAAAGGAGTTGGG
GTTGAAATGAAATTTGAAAC

Product: arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQ
DLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGAL
TQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEI
LKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIAKVYRKEST
LNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQ
DKNLDRILVIK

Sequences:

>Translated_491_residues
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQ
DLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGAL
TQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEI
LKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIAKVYRKEST
LNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQ
DKNLDRILVIK
>Mature_491_residues
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQ
DLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGAL
TQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEI
LKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIAKVYRKEST
LNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQ
DKNLDRILVIK

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=590, Percent_Identity=21.3559322033898, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082193, Length=326, Percent_Identity=23.9263803680982, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI221142684, Length=293, Percent_Identity=22.8668941979522, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786909, Length=134, Percent_Identity=28.3582089552239, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54354; Mature: 54354

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDI
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCHHHEEECC
NSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEECC
RNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKVRTEIEKDCNIKALFFLNPTY
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEECCCC
YGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGAL
EEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCHHHHCCCCEEEEEEECCCCCC
TQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLS
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHH
RYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQV
HHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCEEEEEEEEECCCCHHHHHHHHHCEEEEE
ELGDSYNILALVSIGTNKSDIDRLVKALSIIAKVYRKESTLNEFNMVQINPIIKLNPREA
EECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEECCCHH
FYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQ
CCCCCCCCCHHHHHHHHHCCCEECCCCCCCEECCHHHHHHHHHHHHEEEECCCEEEEECC
DKNLDRILVIK
CCCCCEEEEEC
>Mature Secondary Structure
MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGVAILNKYLGESLMKMDI
CCCCCCCHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCHHHEEECC
NSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQAIHAMILSVIKPGEKVLLP
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCEEECC
RNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKVRTEIEKDCNIKALFFLNPTY
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEECCCC
YGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLPPSAISLGADMVAVSIHKTGGAL
EEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCHHHHCCCCEEEEEEECCCCCC
TQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMASIDGARVNLVENGEKQLSKALNLS
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHH
RYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKLCINVKELNLTGFEVYDLLYKNFSIQV
HHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCEEEEEEEEECCCCHHHHHHHHHCEEEEE
ELGDSYNILALVSIGTNKSDIDRLVKALSIIAKVYRKESTLNEFNMVQINPIIKLNPREA
EECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEECCCHH
FYAPKESVEINSCIDRICGESIMAYPPGIPIIAPGELITEEIMEYIIFLKNSNAYLTDVQ
CCCCCCCCCHHHHHHHHHCCCEECCCCCCCEECCHHHHHHHHHHHHEEEECCCEEEEECC
DKNLDRILVIK
CCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]