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The map label for this gene is ycbM [H]

Identifier: 126698401

GI number: 126698401

Start: 996378

End: 997313

Strand: Direct

Name: ycbM [H]

Synonym: CD0821

Alternate gene names: 126698401

Gene position: 996378-997313 (Clockwise)

Preceding gene: 126698400

Following gene: 126698402

Centisome position: 23.22

GC content: 37.71

Gene sequence:

>936_bases
ATGAAAATGGATGAACAAACGATAATTCTTTTCTTACTCTTGCTGTCGATTGGTCTACTTTTTCTTTCCATATTTGCTTT
TTCAAAGCTTGGGCATATTTACAAGCGCCTAAAAGATATAGAGGAGATACTGGCTGATGTAGAAATTGGAGACGAAAATC
GTAAAATACTAATTAAGCCATGTGATGTTATGGCTCCATTGGTTTATCAGCTTAATGAGATTGTCTACGATTATGAAAAT
AAGTTACTTTCTCTGAAAAAGTCGGATAAAGCTAGCAAACAACTTATGACAAGTTTATCTCATGATGTTCGTACACCATT
AACAACTCTGATTGGTTATCTGGATGCTGTACACAGTGGTATAGTTATCGAACAAGAGCGGGAGGAATACCTTGAAATCG
CTAGGCGTAGAGCCTACGACCTCAAGGATTACATTGATGTTCTTTTTGACTGGTTTCGGTTGAACTCTGATGAATTTACG
CTGTCAATAGAATCTGTGGAAATTGCAGAGTTGTCACGCAATATTTTGAAAGACTGGATTCCTATATTCCATGAAAAGAA
ACTGAATTTTGAAATTGATATTCCAGAAAATCGACTAATGGTAAACCTCGACCCAGATGGATATTCCCGTGTGGTCAATA
ATCTGGTTCAAAATGTTCTTGCTCACAGTAAGGCTCGGCAAATCAAGATTACCATGAGTGAGGATTCCAGAATGGTATTA
CTCCGTGTTGAGGATGATGGTGTTGGGATTGCCAGAGAAAATTTACCACATATTTTTGAGCGACTGTATAAGTGTGATAA
AGGACGTTCAGAAAAAGGAAGTGGTCTTGGTCTATCTATTGTCAGTCAAATGGTGGAGCGAATGGGTGGTCAGGTTTCCG
TAGAAAGTGAGATTGGAAAGTATACCGTATTTACAGTGAGCTTACCATTAATATAA

Upstream 100 bases:

>100_bases
CTATTATCAGTCGCCTAAGAAAAAAAATTGAACTAGACCCATCATCTCCCATCTATTTGCAAACAATAAAAGGAATTGGG
TATCAATTCAACACGGAGGT

Downstream 100 bases:

>100_bases
AATTGTTTTTCCCCCATGTGACATGTATACACAGGGGGATTTTTTGTAAGTTATAAAGTTGCAAGGTTAATACAAGGTTG
TTGCAAGGTTAATGTAAGAT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEILADVEIGDENRKILIKPCDVMAPLVYQLNEIVYDYEN
KLLSLKKSDKASKQLMTSLSHDVRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQNVLAHSKARQIKITMSEDSRMVL
LRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGLGLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI

Sequences:

>Translated_311_residues
MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEILADVEIGDENRKILIKPCDVMAPLVYQLNEIVYDYEN
KLLSLKKSDKASKQLMTSLSHDVRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQNVLAHSKARQIKITMSEDSRMVL
LRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGLGLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI
>Mature_311_residues
MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEILADVEIGDENRKILIKPCDVMAPLVYQLNEIVYDYEN
KLLSLKKSDKASKQLMTSLSHDVRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQNVLAHSKARQIKITMSEDSRMVL
LRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGLGLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=29.004329004329, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=29.9107142857143, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=26.1802575107296, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=25.6809338521401, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=25.4166666666667, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=26.6968325791855, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=24.2798353909465, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=29.5964125560538, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=24.8908296943231, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=23.2484076433121, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790567, Length=203, Percent_Identity=30.5418719211823, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=25.7383966244726, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082128, Length=221, Percent_Identity=25.7918552036199, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=26.2135922330097, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 35772; Mature: 35772

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEILADVEIGDENRKILIKP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
CDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHDVRTPLTTLIGYLDAVHSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFTLSIESVEIAELSRNILKDWI
CEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
PIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQNVLAHSKARQIKITMSEDSRMVL
HHHHCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
LRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGLGLSIVSQMVERMGGQVSVESEIGK
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCC
YTVFTVSLPLI
EEEEEEEECCC
>Mature Secondary Structure
MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEILADVEIGDENRKILIKP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
CDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHDVRTPLTTLIGYLDAVHSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFTLSIESVEIAELSRNILKDWI
CEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHH
PIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQNVLAHSKARQIKITMSEDSRMVL
HHHHCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
LRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGLGLSIVSQMVERMGGQVSVESEIGK
EEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCC
YTVFTVSLPLI
EEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]