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The map label for this gene is regX3 [H]

Identifier: 126698400

GI number: 126698400

Start: 995689

End: 996381

Strand: Direct

Name: regX3 [H]

Synonym: CD0820

Alternate gene names: 126698400

Gene position: 995689-996381 (Clockwise)

Preceding gene: 126698399

Following gene: 126698401

Centisome position: 23.21

GC content: 36.94

Gene sequence:

>693_bases
ATGAATAAAGTTTTAATTATAGATGATGATAAAGATCTTTGTATTTTGTTAAAAAAGAGTATTTCAATTGAACAGATTGA
AGCAAACTATTGCCATTCTGGGAGAGATGGACTGGTTGAACTTTCAAAACAAGATTATCAGTTAGTAGTTCTAGACGTGA
TGATGCCAGGTATGGATGGTTTTGAAACTATGGAACAAATACGAAAATATAGCAGTATTCCCATCTTAATGCTGACATCA
AAAAGCGATAATTACAGCAAAGTGCATGGATTGCGAGCTGGTGCAGATGACTATCTAACCAAACCATTTGAAATTACAGA
ATTTACTGCTCGTGTACTGTCTTTAATCCGACGTTACACCCGTTTTAATCCAAAAAATGAGGAGCCACAGCAACTTTCTT
TCAAAGGTTTGTTGATTGACCTTGACCAGCATACAGTTACTACCAATGGCGAACCTATGTTGCTTCCACCCAAGGAATTT
GGTGTACTTCTTTACTGTGCAAGGCATCAGGGTAAGATTTTGACAAAACAGCAGATTTATGAAGCCGTGTGGGGTGAGCC
ATATGTATATGATGACAGCAATATCATGGCTATTATCAGTCGCCTAAGAAAAAAAATTGAACTAGACCCATCATCTCCCA
TCTATTTGCAAACAATAAAAGGAATTGGGTATCAATTCAACACGGAGGTATGA

Upstream 100 bases:

>100_bases
TCATTGAGGAGCATATTCTAAATGATGTAAAGATACTACAATATGACTAAATTCCTAGTGATAAAAAAGTCTACGAATGA
GTGTAGAAAGGGGAACTAAG

Downstream 100 bases:

>100_bases
AAATGGATGAACAAACGATAATTCTTTTCTTACTCTTGCTGTCGATTGGTCTACTTTTTCTTTCCATATTTGCTTTTTCA
AAGCTTGGGCATATTTACAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTS
KSDNYSKVHGLRAGADDYLTKPFEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV

Sequences:

>Translated_230_residues
MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTS
KSDNYSKVHGLRAGADDYLTKPFEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV
>Mature_230_residues
MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTS
KSDNYSKVHGLRAGADDYLTKPFEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV

Specific function: Part of the two-component regulatory system senX3/regX3. Once phosphorylated by senX3, activates the expression of several operons/genes involved in phosphate assimilation and metabolism, such as pstSCAB, phnDCE, and phoA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.0357142857143, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=32.4561403508772, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.15859030837, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=33.7777777777778, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=33.4782608695652, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=29.9145299145299, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=29.3859649122807, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=31.140350877193, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.0748898678414, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=27.4678111587983, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=27.7533039647577, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=25.7510729613734, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=28.1818181818182, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=28.0575539568345, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790437, Length=181, Percent_Identity=27.6243093922652, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26405; Mature: 26405

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDG
CCEEEEEECCCCEEEEEECCCCEEEEEHHCCCCCCCCEEEECCCCCEEEEEEEECCCCCC
FETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKPFEITEFTARVLSLIRRYT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
RFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEFGVLLYCARHQGKILTKQQIY
HCCCCCCCCCCEEEEEEEEECCCEEEECCCCEEEECHHHCCEEEEEECCCCCEECHHHHH
EAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV
HHHCCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCC
>Mature Secondary Structure
MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQDYQLVVLDVMMPGMDG
CCEEEEEECCCCEEEEEECCCCEEEEEHHCCCCCCCCEEEECCCCCEEEEEEEECCCCCC
FETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKPFEITEFTARVLSLIRRYT
HHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHH
RFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEFGVLLYCARHQGKILTKQQIY
HCCCCCCCCCCEEEEEEEEECCCEEEECCCCEEEECHHHCCEEEEEECCCCCEECHHHHH
EAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQTIKGIGYQFNTEV
HHHCCCCEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA