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The map label for this gene is stc [H]

Identifier: 126698386

GI number: 126698386

Start: 979026

End: 980402

Strand: Direct

Name: stc [H]

Synonym: CD0806

Alternate gene names: 126698386

Gene position: 979026-980402 (Clockwise)

Preceding gene: 126698385

Following gene: 126698389

Centisome position: 22.82

GC content: 30.94

Gene sequence:

>1377_bases
ATGAAAGAGCAGTGGTATAAGGATATATTTGCAAGAGTATTATCTATGACTGATGATGGTTTTATTGTTGTAAATACAAG
TGGAGTAATAATAGATATTAATGATAAATATTGTGACTTTTTAGGAAAAGAAAGAAAAGATATAATAGGACAAAATATAC
AAAGTATTATACCAAATACAAAAATGCTAGATGTTATGAAAAATAAGTATTGTGAAGAAGGAGCTATACATCATTATTCA
GGTGGAAATACAAAAGAAAAAAGTGTAATAGTAAGTAGGTCTTATGTGGAAAATGACAATGGAGAAGTAGTTGCAGGAGT
AGCTCAAGTTAAATTTAGATTGCAATCATTTGATGTAGCTAAAAAGTTAATGTCAGAATATATGGAGCTCCAATATTATA
AAGAGCAGTTTAAGGATAACTGTGGTTTTGACAAGCTCATAGGTGAAAATAGAGACTTCATAGAACTTAAGAAAACAGGT
GTGAAAGCTTCTAAAACAAACTTTCCAGTACTTTTAACGGGTGAAACAGGTACAGGAAAAGAAGTCTTTGCTAGAGCAAT
TCACAATAATAGCAGTAGGTCAGATAAACCTATGGTTAGTATAAACTGCGCTGCAATACCAGAAGAATTATTAGAGTCAG
AGCTATTTGGCTATGACGAAGGAGCTTTTACAGGAGCAAAAAAGGGTGGTAAAAAAGGTAAGTTTTTAGTTGCGAATAAT
GGTACAATCTTTTTAGACGAGATAGGTGACATGCCTTTGACCATGCAAGCAAAACTTTTAAGAGTTCTTCAGGAAAGTGA
GATAGAACCAGTGGGAGGTCTTAAAACTATAAAGATAGATGTAAGAGTAATCTCTGCCACAAGAAAGAATTTAAGTAAAA
TGGTTGAAGAGGGATTATTTAGAGAAGACCTATACTATAGATTAAATGTAATAAACATTCATATGATGGAATTGAAGGAC
AGGCAAGATGATATTTTATTGCTAGCAAATTATATATTAAACAAATTAAATGTTGAATACAAGGAATTGAAGGTTTTAAG
TGATAAGGTTAAAAATTGTTTTATTAACTATACTTGGCCGGGAAATATAAGAGAACTACAAAATGTAATAAAAAGTGCCT
ATGCTGTAAGTGATGATATGGTCATTATGATGTGTGACCTTCCATCTAAGATGGATAATATCAGCAGAGTAGCTCAATGT
AATGTGGATAGCAATTGTTCAATTCATGAAATGGTTGAGAATTATGAAAAGAGCTTAATTATTGATGTGTTAAGGAAGTA
TAATTGGAAATGTTCTAAGGCAGCAGAGGTTATGGGAATACACAAGAGTCTTTTATATAAGAAAATAAAAAAGTATGAAA
TTGAATTAAATAATTAA

Upstream 100 bases:

>100_bases
AACTTTTAGAAAACATTGAATATGTAGAATGATAAGTCTTATAATATTGTATTGTAAGACTTATTATTTTTGCTGAAGGT
TATAGTGGGGAGATGAAACA

Downstream 100 bases:

>100_bases
GATAAATTGAATTAAGGCAATGCTAAAAAAGCGCCTTTATTCAAAGCGAACTGTATAAACTGTTTTATGCAGTTAAAACG
TGTAAAAGTAGATGTGAAGT

Product: sigma-54-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYS
GGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANN
GTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKD
RQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQC
NVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN

Sequences:

>Translated_458_residues
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYS
GGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANN
GTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKD
RQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQC
NVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN
>Mature_458_residues
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYS
GGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANN
GTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKD
RQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQC
NVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=417, Percent_Identity=35.9712230215827, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1789233, Length=459, Percent_Identity=37.037037037037, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=39.8773006134969, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788905, Length=299, Percent_Identity=40.8026755852843, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1790299, Length=367, Percent_Identity=34.3324250681199, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1790437, Length=283, Percent_Identity=42.756183745583, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI1789087, Length=419, Percent_Identity=35.0835322195704, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=36.5625, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=39.1025641025641, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=36.7601246105919, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=35.126582278481, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081858, Length=299, Percent_Identity=29.4314381270903, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=32.034632034632, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52218; Mature: 52218

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGQNIQSIIPNT
CCHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCHHHHHHCCHHHHHHHCCHHHHCCCC
KMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVA
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEHEEECCCCCEEEEHHHHHHHHHHHHHH
KKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTGVKASKTNFPVLLTGETGTGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEHHHCCCCCCCCCCCEEEECCCCCCH
EVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANN
HHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
GTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLF
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCH
REDLYYRLNVINIHMMELKDRQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWP
HHCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECC
GNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQCNVDSNCSIHEMVENYEKSLI
CCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKERKDIIGQNIQSIIPNT
CCHHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCHHHHHHCCHHHHHHHCCHHHHCCCC
KMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGEVVAGVAQVKFRLQSFDVA
HHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEHEEECCCCCEEEEHHHHHHHHHHHHHH
KKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTGVKASKTNFPVLLTGETGTGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEHHHCCCCCCCCCCCEEEECCCCCCH
EVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGYDEGAFTGAKKGGKKGKFLVANN
HHHHHHHHCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
GTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKTIKIDVRVISATRKNLSKMVEEGLF
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCH
REDLYYRLNVINIHMMELKDRQDDILLLANYILNKLNVEYKELKVLSDKVKNCFINYTWP
HHCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECC
GNIRELQNVIKSAYAVSDDMVIMMCDLPSKMDNISRVAQCNVDSNCSIHEMVENYEKSLI
CCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
IDVLRKYNWKCSKAAEVMGIHKSLLYKKIKKYEIELNN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA