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The map label for this gene is etfA [H]

Identifier: 126698385

GI number: 126698385

Start: 977905

End: 978927

Strand: Direct

Name: etfA [H]

Synonym: CD0805

Alternate gene names: 126698385

Gene position: 977905-978927 (Clockwise)

Preceding gene: 126698384

Following gene: 126698386

Centisome position: 22.79

GC content: 34.41

Gene sequence:

>1023_bases
ATGATGAGAGCAAAAGTTAATCAAGGTATAAATTTAAATGATTATAATGGTGTTTGGGTAATAGGAGAGCAAAGGGAAGG
TAAAATTAATCCTGTTACGATAGAACTTATTGGTGAAGGAAGAAAGCTTGCTGACCAATTAGGAAAAGAGCTTGCAGTTG
TGATAGCTGGATATGAAGTAGAGAAAGAAGTGAAGGAATTACTTCACTATAGTGTTGATAAAGTATATTACATCAATGAC
CCTCTTCTTAAAGATTTCACTACTGATGGATATGCAATTTCAATTGCAAATTTAATTGAAAGAAAAAAGCCAGAGGTTGT
ATTGGTTGGTGCTACTTCTATAGGAAGAGATATAGCGCCTAGAATTGCAGGTAAGGTTGGAACAGGTCTAACTGCTGACT
GTACAAAACTTGAAATAGATTCAACAGATAATAAGTTATTACAAACAAGACCAGCATTTGGTGGAAATTTAATGGCCACT
ATTGTTTGTCCAAAAAATAGACCACAGATGTCAACAGTTCGTCCAGGAGTTATGGCAAAAGCTGTAAGAAACGAATCAGA
GACTGGAATTTTAGAAGTTGTTACTCCAGAACTTACTGAAAAAATGATTAGAACTAGATTAGTAGAGATACTTCCACAAG
AAAAGAAATCTGTAAATCTAACTGATGCTAGAATAATAGTATCAGGAGGAAGAGGATTAAAAAGAGCAGAAGGATTTGAG
CTTATAAAAGAATTGGCTGATAAATTGGGGGCAGAGATTGGTGCTTCAAGAGCAGCAGTAGATTCAGGGTGGATAGAACA
TTCTCATCAAGTGGGACAAACAGGAACTACTGTTAGACCAGAACTATACATTGCATGTGGAATATCTGGAGCAATACAAC
ATTTAGCAGGTATGAGTGATTCTAAATATATAGTTGCTATAAATAAAGATGCAAAAGCCCCTATTTTTAGTATATGTGAC
TATGGAATAGTAGGAGATTTATATGAAATTATACCTGAAATGATAGAATCATTAAATAGGTAA

Upstream 100 bases:

>100_bases
GACAAGCATAATGAAATAATAGAAGGTATAAATAAAAAAGAAAAAGCTGAGAAACTAATAGAAATACTATTCGATTTGAA
ACTAGTATAGGAGTGTTAAG

Downstream 100 bases:

>100_bases
CTTTTAGAAAACATTGAATATGTAGAATGATAAGTCTTATAATATTGTATTGTAAGACTTATTATTTTTGCTGAAGGTTA
TAGTGGGGAGATGAAACAAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYIND
PLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFE
LIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICD
YGIVGDLYEIIPEMIESLNR

Sequences:

>Translated_340_residues
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYIND
PLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFE
LIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICD
YGIVGDLYEIIPEMIESLNR
>Mature_340_residues
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYIND
PLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFE
LIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICD
YGIVGDLYEIIPEMIESLNR

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=351, Percent_Identity=36.7521367521368, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI189181759, Length=240, Percent_Identity=44.5833333333333, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI1787990, Length=338, Percent_Identity=32.2485207100592, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786226, Length=338, Percent_Identity=28.9940828402367, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082157, Length=240, Percent_Identity=29.5833333333333, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=344, Percent_Identity=38.0813953488372, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6325261, Length=300, Percent_Identity=35, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI17136898, Length=342, Percent_Identity=34.7953216374269, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24652801, Length=342, Percent_Identity=34.7953216374269, Blast_Score=187, Evalue=9e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 37058; Mature: 37058

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEEECCHH
EKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAP
HHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEEEHHHHHHCCCCCEEEEECHHCCCHHHH
RIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATIVCPKNRPQMSTVRPGVMAK
HHHHHCCCCCCCCCEEEEECCCCCHHEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
AVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFE
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSD
HHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCEECCCEEEEECCHHHHHHHHCCCC
SKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEMIESLNR
CCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLADQLGKELAVVIAGYEV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHCCEEEEEEECCHH
EKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERKKPEVVLVGATSIGRDIAP
HHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEEEHHHHHHCCCCCEEEEECHHCCCHHHH
RIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMATIVCPKNRPQMSTVRPGVMAK
HHHHHCCCCCCCCCEEEEECCCCCHHEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHH
AVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSVNLTDARIIVSGGRGLKRAEGFE
HHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHH
LIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGTTVRPELYIACGISGAIQHLAGMSD
HHHHHHHHHHHHHCCCHHHHHCCHHHHCCCCCCCCCEECCCEEEEECCHHHHHHHHCCCC
SKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEMIESLNR
CCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA