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The map label for this gene is 126698308

Identifier: 126698308

GI number: 126698308

Start: 890080

End: 892206

Strand: Direct

Name: 126698308

Synonym: CD0728

Alternate gene names: NA

Gene position: 890080-892206 (Clockwise)

Preceding gene: 126698307

Following gene: 126698309

Centisome position: 20.75

GC content: 35.64

Gene sequence:

>2127_bases
ATGAATCTATATAATATAATCTTTACAGGGTCAGAACAAGCTTTAGGTGCGGCTCAAGCTATGTTAGCTGAAGCTATAGA
AAAGAATGGAAAAGAGCATAAAGTTGCTTTCCCTGATACAGCATATTCATTACCTTGTATATATGCTGCAACAGGACAAA
AGATGAACACTTTAGGGGACTTAGAAGGTGCTTTAGAAGTAGTAAAATCTTTAATAAATAGAACTCATTTACTAGAACAT
GCTTTTAATGCTGGTTTAGCTACAGCTTTAGCAGCAGAAGTAATTGAAGCATTAAAATATTCAACTATGGATGCTCCATA
TAGTGAGCCATGTGCAGGTCATATAACTGACCCTATAATCAGATCACTTGGTGTACCATTAGTTACAGGAGATATACCTG
GTGTTGCAGTTGTTCTTGGTGAGTGTCCAGATGCAGAATCAGCAGCAAAAGTTATAAAAGATTACCAATCTAAAGGTTTA
CTAACTTTCTTAGTTGGTAAAGTTATAGACCAAGCTATAGAAGCTGGAGTAAAAATGGGTCTTGAGCTAAGAGTTATACC
TCTAGGATATGATGTAACTTCTGTTATACACGTTGTATCTGTTGCAGTAAGAGCAGCATTAATATTCGGTGGATTAACTC
CTGGTGATTTAAACGGATTATTAGAGTACACAGCTAATAGAGTTCCTGCATTTGTTAATGCATTTGGACCATTAAGTGAA
TTAGTTGTATCTGCAGGTGCTGGAGCAATAGCTTTAGGATTCCCAGTTATAACTGACCAAACAGTTCTTGAAGTTCCAAT
GAACCTATTAACTCAAAAAGATTACGATAAGATAGTAGCTACTTCATTAGAAGCTAGAGGAATAAAAATAAAAGTTACTG
AAATACCTATCCCAGTTTCATTTGCAGCAGCATTTGAAGGTGAGAGAATTAGAAAGAGCGATATGTTTGCTGAGTTTGGT
GGAAACAGAACTGAAGCTTGGGAGCTTGTTGTTAAGAAAGAAGCAACAGAAGTTGAAGACCATAAGATAGAAATAATAGG
ACCAAATATAGATGAAGTTGATGCAGATGGTGTATTAAGATTACCACTTGCTGTAATAGTTAAAATAGCTGGTAAAAATA
TGCAAGAAGATTTCGAGCCAGTTCTTGAAAGACGTTTCCACTACTTCTTAAACTATATAGAAGGTGTAATGCACGTTGGA
CAAAGAGATATGGCTTGGGTAAGAATCTCTAAAGATGCATTTGATAAAGGATTTAGACTTGAGCATATAGGAGAAGTTTT
ATATGCTAAGATGTTAGATGAATTTGAATCAGTAGTTGATAAGTGTGAAATAACTATAATTACAGATGCTGAAAAAGTTT
CTGAATTAAAAGGTGAAGCAATAGCTAAGTACAATGCTAGAGATGAAAGATTAGCTTCATTAGTTGATGAAAGTGTTGAC
ACTTTCTATTCTTGTAACTTATGTCAATCATTTGCACCAGCTCACGTTTGTGTTGTTACTCCTGAAAGACTTGGTCTTTG
TGGAGCAGTTAGCTGGTTAGATGCTAAGGCTACTAAAGAATTAGACCCAACAGGTCCTTGTCAACCAATAGAAAAAGGCG
AGTGCTTAGATGATAGAACAGGTGTATGGAATTCAGTAAATGAAACTGTAAACCAAATATCTCAAGGTGCAGTTGAATCT
GTTACATTATACTCTATACTAGAAGACCCAATGACTTCTTGTGGATGCTTCGAATGTATCTGTGGTATAATGCCAGAAGC
AAATGGATTTGTTGTAGTTAACAGAGAATTTGCAAGTGTTACTCCAGTTGGTATGACTTTCGGAGAACTTGCTTCTATGA
CAGGTGGAGGAGTTCAAACTCCAGGATTTATGGGACACGGAAGACATTTCATATCTTCTAAAAAATTCGCTTATGCAGAA
GGTGGACCAGAAAGAATAGTTTGGATGCCAAAAGAATTAAAAGATTATGTAGCTGATAAATTAAATGCTACAGTTAAAGA
AATGACTGGAATAGAAAACTTCTGTGATATGGTTTGTGATGAAACTATAGCTGACGATTCTGAAGGAGTATTAGCTTTCT
TAGAAGAAAAAGGTCATCCAGCATTAGCTATGGAAAGTGTAATGTAA

Upstream 100 bases:

>100_bases
CAGACTCTTTCTTAGAGTTAAATGAAGGTGGATTTGCTTTCTAGGGTTTTTAGGGTATAGTTAATAAAAAATAGGTGTAA
ATATTAAAGGGGGAAATAGA

Downstream 100 bases:

>100_bases
TTGATGGAAAATTTAAAATAATATGATATAATATTAATATGATTTAAGTAATTTAATCAATAATATAATATTGGGGGTCT
ATCGAAATGAAATTATTACC

Product: bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta

Products: NA

Alternate protein names: ACS subunit; Acetyl-CoA synthase subunit; CODH/ACS [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSLPCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEH
AFNAGLATALAAEVIEALKYSTMDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLNGLLEYTANRVPAFVNAFGPLSE
LVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYDKIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFG
GNRTEAWELVVKKEATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNYIEGVMHVG
QRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDAEKVSELKGEAIAKYNARDERLASLVDESVD
TFYSCNLCQSFAPAHVCVVTPERLGLCGAVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVES
VTLYSILEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFMGHGRHFISSKKFAYAE
GGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDETIADDSEGVLAFLEEKGHPALAMESVM

Sequences:

>Translated_708_residues
MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSLPCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEH
AFNAGLATALAAEVIEALKYSTMDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLNGLLEYTANRVPAFVNAFGPLSE
LVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYDKIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFG
GNRTEAWELVVKKEATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNYIEGVMHVG
QRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDAEKVSELKGEAIAKYNARDERLASLVDESVD
TFYSCNLCQSFAPAHVCVVTPERLGLCGAVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVES
VTLYSILEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFMGHGRHFISSKKFAYAE
GGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDETIADDSEGVLAFLEEKGHPALAMESVM
>Mature_708_residues
MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSLPCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEH
AFNAGLATALAAEVIEALKYSTMDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLNGLLEYTANRVPAFVNAFGPLSE
LVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYDKIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFG
GNRTEAWELVVKKEATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNYIEGVMHVG
QRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDAEKVSELKGEAIAKYNARDERLASLVDESVD
TFYSCNLCQSFAPAHVCVVTPERLGLCGAVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVES
VTLYSILEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFMGHGRHFISSKKFAYAE
GGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDETIADDSEGVLAFLEEKGHPALAMESVM

Specific function: The beta subunit generates CO from CO(2), while the alpha subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the alpha subunit by a corrinoid ir

COG id: COG1614

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004461
- InterPro:   IPR011254
- InterPro:   IPR016099 [H]

Pfam domain/function: PF03598 CdhC [H]

EC number: =2.3.1.169 [H]

Molecular weight: Translated: 76589; Mature: 76589

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSLPCIYAATGQKMNTLGD
CCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHH
LEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYSTMDAPYSEPCAGHITDPII
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
RSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGLLTFLVGKVIDQAIEAGVKMG
HHCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
LELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLNGLLEYTANRVPAFVNAFGPLSE
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHH
LVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYDKIVATSLEARGIKIKVTEIPIPVS
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCEE
FAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKEATEVEDHKIEIIGPNIDEVDADGVLR
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHH
LPLAVIVKIAGKNMQEDFEPVLERRFHYFLNYIEGVMHVGQRDMAWVRISKDAFDKGFRL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCH
EHIGEVLYAKMLDEFESVVDKCEITIITDAEKVSELKGEAIAKYNARDERLASLVDESVD
HHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
TFYSCNLCQSFAPAHVCVVTPERLGLCGAVSWLDAKATKELDPTGPCQPIEKGECLDDRT
HHEEHHHHHHCCCCEEEEECHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GVWNSVNETVNQISQGAVESVTLYSILEDPMTSCGCFECICGIMPEANGFVVVNREFASV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCC
TPVGMTFGELASMTGGGVQTPGFMGHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADK
CCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCCEEEECCHHHHHHHHHH
LNATVKEMTGIENFCDMVCDETIADDSEGVLAFLEEKGHPALAMESVM
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCHHHHHCC
>Mature Secondary Structure
MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSLPCIYAATGQKMNTLGD
CCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHH
LEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYSTMDAPYSEPCAGHITDPII
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
RSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGLLTFLVGKVIDQAIEAGVKMG
HHCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
LELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLNGLLEYTANRVPAFVNAFGPLSE
CEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHH
LVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYDKIVATSLEARGIKIKVTEIPIPVS
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCEE
FAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKEATEVEDHKIEIIGPNIDEVDADGVLR
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHH
LPLAVIVKIAGKNMQEDFEPVLERRFHYFLNYIEGVMHVGQRDMAWVRISKDAFDKGFRL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCH
EHIGEVLYAKMLDEFESVVDKCEITIITDAEKVSELKGEAIAKYNARDERLASLVDESVD
HHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
TFYSCNLCQSFAPAHVCVVTPERLGLCGAVSWLDAKATKELDPTGPCQPIEKGECLDDRT
HHEEHHHHHHCCCCEEEEECHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GVWNSVNETVNQISQGAVESVTLYSILEDPMTSCGCFECICGIMPEANGFVVVNREFASV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCC
TPVGMTFGELASMTGGGVQTPGFMGHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADK
CCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCEEECCCCCCEEEECCHHHHHHHHHH
LNATVKEMTGIENFCDMVCDETIADDSEGVLAFLEEKGHPALAMESVM
HHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1748656 [H]