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The map label for this gene is yvrG [H]

Identifier: 126698248

GI number: 126698248

Start: 810391

End: 811797

Strand: Direct

Name: yvrG [H]

Synonym: CD0669

Alternate gene names: 126698248

Gene position: 810391-811797 (Clockwise)

Preceding gene: 126698247

Following gene: 126698249

Centisome position: 18.89

GC content: 28.78

Gene sequence:

>1407_bases
TTGGATAGTGTAAAGTACATATTGAGGCGATTTATAGGTTCAAGTATCTTGATTTCATTACTTTTTATTGTATTAAATAT
AGCAGGTTTTCTTCTGTTTTCATATATGTTATTTGTATCTAAATACTCTGATAATTTAGATACAAGTGATAGCAGAGAAA
TAAAATCAAACTTGATTATGATTGAAGATAATTTGGTTTTAAAAGATGGAAAGTTTATTTTAGATGATTCTAGTAAGGAA
GTGCTACATAAAAATAAAGTTTGGGCAATGTTAATTGATAACAATGGAGATAGAATATGGGGATTTGATTTACCAAAAGA
AATTCCAAGTCATTATACTTTGACAGATGTAGCAAAGTTTTCAAGGTTCTTTTTAAAGGACTATCCTGTGTATGTATGGG
AACATCCAAATGGAATATTAGTAACAGGTTATCCAAAAGACAAGTACACTAAGTTTAACCTTACTTATACGGTTAAGGAA
ATAGAACAATTTCCTATGTTAATAATAGGTATGTTTCTGGTTAATGCAATAGTTACTTTTTTAATAGCTCTATTCATAGG
TTTAAAAATGGTGAAATCTATAAAGCCAATTATTACTGGCATAAAGCTTATGTCAAAAGGAGAACCAGTACTTTTACAAG
AAAAAGGAATACTAAGTGATATTTCAAAATCTATTAATACTGTATCTAAAGAGTTGCAAATGAAAGATGAAAAACTTAGG
AAGAAAGAGGAAGCTAGGTCTAACTGGATTGCAGGAATATCTCATGATATAAGAACTCCACTTTCAATGATAATTGGATA
TGCTGGAGAACTTGAAGAAAGCAGTAGCCTTTCAAATAGAGAACAAGAGCAAGTGTCTATTATATGCAATCAAGGGATTA
AAATCAGAGAATTAGTAAATGACCTAAATTTAGTGTCTAAACTTGAATATAATATGCAAGCATTGAATTGTGATAAGATT
AGAGTTTCTGCGTTTTTGAGAGAGCTTATTTCTGAGTTTATAAATAATAATTTGGATAATGACTTTTACGTTGAACTTGA
TATACTAAATGAAGATATTATTATAGATGCAGATAAAAAATTATTAAAAAGGGCTATTAGTAATTTAATACAAAATAGTA
TAACTCATAACCAACAAGGATGTAATATAAGGGTTACCTCTAAGTCTGATTTAGATTTTTGCTATATAATTGTTGAAGAT
GATGGAAAAGGTATGAGTCAAGAAAGAATTAATAGTTTATTAAAGAGCCAAAATGGACTAAGTGAGGCATATGCCAAAGG
TCAAAATCATGGTCTAGGTATTTTGATAGTATCTGGCATTATTAATGCACATAGAGGTAAATTAGATATTACGAGCATTG
ATAGTCAGGGACTAAAAACAATACTAAAATTACCTCTAATTAAGTGA

Upstream 100 bases:

>100_bases
CACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAATTTTAGATATTAGAATAAAAGAAA
TCAAGAGGAGTGATTTAATT

Downstream 100 bases:

>100_bases
TATTTTATAAAATAATAACAGATAAGAATGAAGAATGAAAATATTTTGAAAATAATTTTATTCTTTATTGACAAATTAAC
TCTATTAGAGTAGAATAAGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKE
VLHKNKVWAMLIDNNGDRIWGFDLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLR
KKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKI
RVSAFLRELISEFINNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVED
DGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK

Sequences:

>Translated_468_residues
MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKE
VLHKNKVWAMLIDNNGDRIWGFDLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLR
KKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKI
RVSAFLRELISEFINNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVED
DGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK
>Mature_468_residues
MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKE
VLHKNKVWAMLIDNNGDRIWGFDLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLR
KKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKI
RVSAFLRELISEFINNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVED
DGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=340, Percent_Identity=25.2941176470588, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=24.5833333333333, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=24.896265560166, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=25.609756097561, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=22.093023255814, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=294, Percent_Identity=23.8095238095238, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53131; Mature: 53131

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEE
IEDNLVLKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGFDLPKEIPSHYTLTDVAKF
EECCEEEECCCEEECCCCHHHHHCCCEEEEEEECCCCEEECCCCHHHCCCCCCHHHHHHH
SRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKEIEQFPMLIIGMFLVNAIVTF
HHHHHHCCCEEEEECCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
DLNLVSKLEYNMQALNCDKIRVSAFLRELISEFINNNLDNDFYVELDILNEDIIIDADKK
HHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCHH
LLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGL
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCH
SEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK
HHHHHCCCCCCEEEEEEEHHHHHCCCEEEEECCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSDNLDTSDSREIKSNLIM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCEEE
IEDNLVLKDGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGFDLPKEIPSHYTLTDVAKF
EECCEEEECCCEEECCCCHHHHHCCCEEEEEEECCCCEEECCCCHHHCCCCCCHHHHHHH
SRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKEIEQFPMLIIGMFLVNAIVTF
HHHHHHCCCEEEEECCCEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGILSDISKSINTVSKELQMKDEKLR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSSLSNREQEQVSIICNQGIKIRELVN
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
DLNLVSKLEYNMQALNCDKIRVSAFLRELISEFINNNLDNDFYVELDILNEDIIIDADKK
HHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCHH
LLKRAISNLIQNSITHNQQGCNIRVTSKSDLDFCYIIVEDDGKGMSQERINSLLKSQNGL
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCH
SEAYAKGQNHGLGILIVSGIINAHRGKLDITSIDSQGLKTILKLPLIK
HHHHHCCCCCCEEEEEEEHHHHHCCCEEEEECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]