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The map label for this gene is yvrH [H]

Identifier: 126698247

GI number: 126698247

Start: 809633

End: 810346

Strand: Direct

Name: yvrH [H]

Synonym: CD0668

Alternate gene names: 126698247

Gene position: 809633-810346 (Clockwise)

Preceding gene: 126698242

Following gene: 126698248

Centisome position: 18.87

GC content: 33.19

Gene sequence:

>714_bases
ATGATTATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAAT
CCTGAGAAAAGAGGGATTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAGAAATGTAAAGC
CAGATTGTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTTTCTATTATGAGAAAAATTAGAGAGACATCTAAA
ATACCAGTGATTTTTCTCTCTGCAAGAGGTGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGACGATTATAT
AGTAAAGCCATTTTTACCAAAGGAACTTACTTTAAGGCTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAG
AGGAGTTGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAG
ATTTCTTTAACAGCTAAAGAGCATTCGTTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAATGATTCACT
ATGTCAAGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGGGTTAGAGAGAAGA
TAGAAAAAACTCCATCTACACCTAAACATCTTATTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Upstream 100 bases:

>100_bases
TGGTTACATTTCAATTAGCTGAAATTTACCTTACAATAACCTTAAAAGTCTATTTAGGCAAAGTTGTGAAAATGGGTATA
TGGTATACTAAAGGAGGGTG

Downstream 100 bases:

>100_bases
TTTTAGATATTAGAATAAAAGAAATCAAGAGGAGTGATTTAATTTTGGATAGTGTAAAGTACATATTGAGGCGATTTATA
GGTTCAAGTATCTTGATTTC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MIMESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSK
IPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQE
ISLTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Sequences:

>Translated_237_residues
MIMESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSK
IPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQE
ISLTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN
>Mature_237_residues
MIMESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSK
IPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQE
ISLTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.2422907488987, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=33.9130434782609, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=32.3275862068966, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.9055793991416, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=30.3418803418803, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=31.7596566523605, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.3982300884956, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=29.4642857142857, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.4561403508772, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.6320346320346, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.858407079646, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=27.8260869565217, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=30.5309734513274, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=27.8260869565217, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=31.5315315315315, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26961; Mature: 26961

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILD
CCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEE
VVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRL
EEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCEEECCCCCHHHHHHH
VGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEISLTAKEHSLLLKLYENKGR
HHHHHHEECCCCCCCCCEEEECCEEEEEECHHHHCCCCCEEEEEEHHHHEEEEEECCCCC
IVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN
EEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEECCCEEEEEC
>Mature Secondary Structure
MIMESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFRNVKPDCAILD
CCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCEEEE
VVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRL
EEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCCCEEECCCCCHHHHHHH
VGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEISLTAKEHSLLLKLYENKGR
HHHHHHEECCCCCCCCCEEEECCEEEEEECHHHHCCCCCEEEEEEHHHHEEEEEECCCCC
IVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLITVRGLGYKLMIN
EEECHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]