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The map label for this gene is dnaC [H]

Identifier: 126698203

GI number: 126698203

Start: 748113

End: 749414

Strand: Direct

Name: dnaC [H]

Synonym: CD0626

Alternate gene names: 126698203

Gene position: 748113-749414 (Clockwise)

Preceding gene: 126698202

Following gene: 126698204

Centisome position: 17.44

GC content: 30.8

Gene sequence:

>1302_bases
ATGGGTAAATCAAAAGATGTTGAAATAGAGAAGTCTATTTTAGGCACAATTCTTTTAGACAATAAATTAAGCTATAAGCT
AGATGAATTAAATGAAAACATGTTTATGAATGATATATGTCTTGAGATATTTAAAATTATGAAAGAACTTAAAAAAGAAA
ACATAGTGATTGATGTGGCCACTGTGAAATCAAAGATAGATAGAAAATCTCTAGCAATAAAAACGAGTGATGTGACTAAT
CTAATTACTTGGGGTCAGAATTTTGGTCTTGATGGTCATATTAAAATTTTAAAAGAAAATTTAGCTAGAAGAAGCATAAA
TCAAAACTGCCAAAACCTTTTACACAGCCTAAACCTTGGAGAAAATATCGATACTTGTATTTACAAATTTGAAAGTAATA
TAAAGGAGATTTTGGACAAGGATACTTATGAAAATGATGATGTAAATAGTATAGCAGGGAAGGTGCTTGATTTTTTAGAA
AACAAAAAAGATATTGGATTTAAGTTTGGTATAAAATTACTTGATACCACTATAGGAGGTCTTTTTAAAGGAGAGCTAAC
CACAATAGCAGCTAAATCAGGGGTTGGGAAAACTGCTTTGGCACTTCAAATAATGTTAAATTCATTTAAGCAAGGTAAAA
AAACTTTATTTATAAGTAGAGAAATGACCAGTGAGCAAGTATTTATGAGAAATATATGCAGAGTAACTGGTGTAAGTACA
AGGAATATGAAATCTAAAGAAATAGATGAAAATGATTGGAAACTTATTGTAAATGCTATAGGTGATTTAAGCGAAAATAA
CTTAATTTATATCAATGATAAGATAGATACAATTAGTGCAATTAGAAAGAGGATAAGGCAGGTAAAGCCAGATTTATTAA
TAGTGGATTATGTGCAACTCCTTACATCTCAGAAAAGCATGGATAAGAGAGAAAGGGAGGTAGCTACTTTTTCGAGAGAA
CTTAAAAATATGACTTTAGATTTTAATATACCTGTAATCCAATTAAGTCAGTTAAATGATGAAATGAAAGATTCAAGACC
TTATGGAGATAGACCTATGAGGGATAGCAAAGCCATCTACCACGATAGCAACAATGTGGTTTATATACATCAATTAAAGG
GGAGTGATTATGAAGAAGCAGTGAGAGATATTGGAGAAAGTGAGGAGGCAGTTAGAGCATCAGAATACAGGGGAATTAAG
ATGGTTGATTTAATAGTTGCGAAGTGTAGAGATGGACAGACTAGGCATAAGCATTTTTGTTACTTTGGGGATAAGTTACA
TTTTCAAGAACTAAATTATTAG

Upstream 100 bases:

>100_bases
CATAACAAATAGTGAGTCATAACAAATAATGTATTTATAATTGATAATGTATTTAAAAATCAAAATATAAAAACTTATAA
GGAAAGAGAGATTAATTTAT

Downstream 100 bases:

>100_bases
GTCAATAAAGTAGTAATAACAAGCTTATTAAAAGTCGGGAAATAGCAAATAGATTATAAAATATGAGGTGAAAATATGTT
GGAATTAAGAAAAATTATAG

Product: phage-related replicative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIFKIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTN
LITWGQNFGLDGHIKILKENLARRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFISREMTSEQVFMRNICRVTGVST
RNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKIDTISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRE
LKNMTLDFNIPVIQLSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVRASEYRGIK
MVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY

Sequences:

>Translated_433_residues
MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIFKIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTN
LITWGQNFGLDGHIKILKENLARRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFISREMTSEQVFMRNICRVTGVST
RNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKIDTISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRE
LKNMTLDFNIPVIQLSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVRASEYRGIK
MVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY
>Mature_432_residues
GKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIFKIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNL
ITWGQNFGLDGHIKILKENLARRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLEN
KKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFISREMTSEQVFMRNICRVTGVSTR
NMKSKEIDENDWKLIVNAIGDLSENNLIYINDKIDTISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSREL
KNMTLDFNIPVIQLSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVRASEYRGIKM
VDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=394, Percent_Identity=25.1269035532995, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49680; Mature: 49549

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIFKIMKELKKENIVIDVA
CCCCCCCCHHHHHHHHHEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEH
TVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLARRSINQNCQNLLHSLNLG
HHHHHHCHHHEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLENKKDIGFKFGIKLLDTTIGG
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
LFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFISREMTSEQVFMRNICRVTGVST
HHCCCHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHCCCCC
RNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKIDTISAIRKRIRQVKPDLLIVDYVQL
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHH
LTSQKSMDKREREVATFSRELKNMTLDFNIPVIQLSQLNDEMKDSRPYGDRPMRDSKAIY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEHHHCCHHHHCCCCCCCCCCCCCCCEE
HDSNNVVYIHQLKGSDYEEAVRDIGESEEAVRASEYRGIKMVDLIVAKCRDGQTRHKHFC
ECCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEE
YFGDKLHFQELNY
EECCEECCCCCCC
>Mature Secondary Structure 
GKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIFKIMKELKKENIVIDVA
CCCCCCCHHHHHHHHHEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEH
TVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLARRSINQNCQNLLHSLNLG
HHHHHHCHHHEEEEECCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLENKKDIGFKFGIKLLDTTIGG
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
LFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFISREMTSEQVFMRNICRVTGVST
HHCCCHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHHCCCCC
RNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKIDTISAIRKRIRQVKPDLLIVDYVQL
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHH
LTSQKSMDKREREVATFSRELKNMTLDFNIPVIQLSQLNDEMKDSRPYGDRPMRDSKAIY
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEHHHCCHHHHCCCCCCCCCCCCCCCEE
HDSNNVVYIHQLKGSDYEEAVRDIGESEEAVRASEYRGIKMVDLIVAKCRDGQTRHKHFC
ECCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEE
YFGDKLHFQELNY
EECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]