Click here to switch to the map view.

The map label for this gene is bglA [H]

Identifier: 126697958

GI number: 126697958

Start: 459275

End: 460741

Strand: Direct

Name: bglA [H]

Synonym: CD0389

Alternate gene names: 126697958

Gene position: 459275-460741 (Clockwise)

Preceding gene: 126697957

Following gene: 126697959

Centisome position: 10.71

GC content: 31.08

Gene sequence:

>1467_bases
ATGAGAAAGTTTCCAGAAGGATTTCTTTGGGGAGGAGCTACAGCTGCTAATCAATTTGAAGGTGGTTGGAATTTAGGTGG
TAAAGGGTGGTCTGTATCAGATGTAGCAAAGGCACACTTTGATGCAGATGTGAAAGATTATAAATCTAATAATGAAATCA
CAACAAAAGATATAGAAGAAGGATTAGCACATCCTGAAGATGAAGTAAATTATCCAAAACGTCATGGTAGTGATTTTTAT
CATCACTATAAAGAAGATATTGCTCTAATGGCAGAAATGGGATTTAAGACATATCGAATGAGTATTGCTTGGTCTCGTAT
TTTTCCAAATGGAGATGATAAAGAGCCAAATGAAGAAGGTTTACAGTTTTATGATGATGTATTTGATGAGTTGATAAGTT
ATGGAATTGAACCACTTGTTACTATGTCACATTATGAACCACCATTAAATATCGTTTTAAACTATGATGGATGGTATTCA
CGACAAGTTATCAATATGTTTGTTAGGTATGTAGAAACTATCTGTGAAAGATATAAAAACAAAGTGAAATATTGGCTTAC
ATTTAATGAAGTTGATTCTATGATTCGTCATCCGTACACTACTGGTGGTTTAGTTCGAGACCGTTTTAAGGATAAAAACT
TTGAGGAAGTTATTTTTCAAGCTATGCATCATCAATTTGTAGCTAGTGCCCTTGCAACAAAAATTTGTCATGAGATTATT
CCAAATTCAAAAGTAGGGTGTATGTTAACAAAATTAACGTATTATCCATATACATGTAGACCAGAAGATGTTTTGGCAAC
TCAACAAAAAATGAGAAGTATTTATGCATATAGTGATACGCAGGTTTTTGGTGAGTATCCAGTATATTTACTGTCGTATT
TTAAAAATAATAACATTCAAATAGTAAAAGAAGAACATGATGATGAAATTATGAAAAAGTATCCAGTAGATTTTATTTCA
TTCTCTTACTATATGTCTTCTTGTGAGGCAGCTGATACAACTGGATTAGATATTACACCTGGGAATACGTTATTAGCTGT
AAAAAATCCTTATTTAGAAATGAGTGAATGGGGTTGGCAAATTGATTCAATAGGTCTACGTATATCTTTGATTGAATTAT
ATGATAGATACAGAAAGCCTTTATTTATAGTTGAAAATGGATTAGGAGCTAAAGATATTTTAACTGAAGATAAAAAAGTT
CATGACCAATATAGAATTAATTATTTAAAAGAACACTTTAAATGTATGTTAGATGCGATTATTGAAGATGGTGTTGAACT
TTGGGGATATACTTCATGGGGTTGTATTGATTTGGTCAGTGAATCAACGAAACAAATGTCAAAACGTTATGGATATATTT
ATGTGGATGCTGATGACTATGGAAAGGGGACATATAATCGATATAAGAAAGATAGTTTTTATTGGTATAAAAAGGTAATT
GAAAATAATAGTATAGATTTTAAATGA

Upstream 100 bases:

>100_bases
ACAATAATGGAGCAGATTATGCTTATAAAGTGTTAAACCAGTCTTATGGCAATGTAAAAAAAGGAAGTATCTTGTTTGAT
GTAAAGGGAGGAATATAAAT

Downstream 100 bases:

>100_bases
CCAATAGAAGGTGAGCAAATAAAATGAACTACATAATAAAGAAAGTTTTGAACTCGAGCGTTGTTTTAGTTCATGACACA
AAGGATAATGAATTTATTTT

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADVKDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFY
HHYKEDIALMAEMGFKTYRMSIAWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVIFQAMHHQFVASALATKICHEII
PNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYAYSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFIS
FSYYMSSCEAADTTGLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKDILTEDKKV
HDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRYGYIYVDADDYGKGTYNRYKKDSFYWYKKVI
ENNSIDFK

Sequences:

>Translated_488_residues
MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADVKDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFY
HHYKEDIALMAEMGFKTYRMSIAWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVIFQAMHHQFVASALATKICHEII
PNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYAYSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFIS
FSYYMSSCEAADTTGLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKDILTEDKKV
HDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRYGYIYVDADDYGKGTYNRYKKDSFYWYKKVI
ENNSIDFK
>Mature_488_residues
MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADVKDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFY
HHYKEDIALMAEMGFKTYRMSIAWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVIFQAMHHQFVASALATKICHEII
PNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYAYSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFIS
FSYYMSSCEAADTTGLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKDILTEDKKV
HDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRYGYIYVDADDYGKGTYNRYKKDSFYWYKKVI
ENNSIDFK

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=505, Percent_Identity=26.7326732673267, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI110681710, Length=511, Percent_Identity=28.5714285714286, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI24497614, Length=492, Percent_Identity=27.6422764227642, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI28376633, Length=497, Percent_Identity=26.7605633802817, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI13273313, Length=500, Percent_Identity=25.2, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1789070, Length=488, Percent_Identity=48.9754098360656, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI2367174, Length=486, Percent_Identity=48.7654320987654, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI2367270, Length=488, Percent_Identity=48.7704918032787, Blast_Score=470, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17552856, Length=500, Percent_Identity=27, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17539390, Length=489, Percent_Identity=25.7668711656442, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI21356577, Length=514, Percent_Identity=25.4863813229572, Blast_Score=138, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 57160; Mature: 57160

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADVKDYKSNNEITTKDIEE
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
GLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSIAWSRIFPNGDDKEPNEEG
HCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCCCCCCHHH
LQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYSRQVINMFVRYVETICERYKN
HHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
KVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVIFQAMHHQFVASALATKICHEII
CEEEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYAYSDTQVFGEYPVYLLSYFKNNNIQ
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCCCEE
IVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTTGLDITPGNTLLAVKNPYLEMSEWGWQ
EEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCEEHHHCCCE
IDSIGLRISLIELYDRYRKPLFIVENGLGAKDILTEDKKVHDQYRINYLKEHFKCMLDAI
EECCCCEEHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IEDGVELWGYTSWGCIDLVSESTKQMSKRYGYIYVDADDYGKGTYNRYKKDSFYWYKKVI
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHCCCHHHHHHHHH
ENNSIDFK
CCCCCCCC
>Mature Secondary Structure
MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADVKDYKSNNEITTKDIEE
CCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCHHHHHH
GLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSIAWSRIFPNGDDKEPNEEG
HCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCCCCCCHHH
LQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYSRQVINMFVRYVETICERYKN
HHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
KVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVIFQAMHHQFVASALATKICHEII
CEEEEEEHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYAYSDTQVFGEYPVYLLSYFKNNNIQ
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHCCCCEE
IVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTTGLDITPGNTLLAVKNPYLEMSEWGWQ
EEECCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCEEHHHCCCE
IDSIGLRISLIELYDRYRKPLFIVENGLGAKDILTEDKKVHDQYRINYLKEHFKCMLDAI
EECCCCEEHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IEDGVELWGYTSWGCIDLVSESTKQMSKRYGYIYVDADDYGKGTYNRYKKDSFYWYKKVI
HHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHCCCHHHHHHHHH
ENNSIDFK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]