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The map label for this gene is apeB [H]

Identifier: 126697901

GI number: 126697901

Start: 396459

End: 397757

Strand: Direct

Name: apeB [H]

Synonym: CD0329

Alternate gene names: 126697901

Gene position: 396459-397757 (Clockwise)

Preceding gene: 126697900

Following gene: 126697902

Centisome position: 9.24

GC content: 29.87

Gene sequence:

>1299_bases
ATGGATAGTATAAACTTTGCTAAAAACTTAATAGACTTCATATATGATAGTCCGTCGTCTTTTCATGCAGTCGAGAGTAC
TAAGGAAATCTTAGATAAAAATGGATTTGAAGAATTAGTTTTGAATCAAAGATGGAATCTAAGAGTTGGTGGAAAGTATT
ATGTTACTAAGAATTTATCAGCTATAGTAGCTTTTGTAGTAAATTCAGAAGGTATAGAAAGAGATGGATTTAGAATAATA
GGCTCTCATTCAGATTCTCCTACATTTAGTATTAAACCAAATGCAGAAATAGAAGCTGAAAAATCTTATTTGAAGTTAAA
TACAGAATGCTATGGAGGAGCAATATTAAGTACATGGTTAGATAGACCTCTTGGGATAGCTGGTAGAGTAGTTTTAAAAG
GTGATAGTATATTAAAACCAAATGAAAGGCTTATAGACTTTAAAAAGCCAATTTGTATAATACCAAATCTAGCAATACAT
TTAAATAGAAGTATAAATGATGGTCACTCATATAATAAGCAAAAAGATATGTTACCTTTAGTTGGGATGTTAAATGATAC
ATTAGAAAAAGATAATTTTCTTATAAAGCAAATAGCATCTAACTTAGATGTAAATATGGAAGATATTATAGATTTTGATT
TATTTTTATATGAATTTGAAAAAGGAAGTTTAATAGGGGCTAATGATGAATTTATATCTATTGGGAGACAAGATAATCTT
GCAATGGTACATGCTAGTTTGAATGCTCTTGTTAATACTAAAGGTCAACATGGTGTAAATGTAATGGCTGTATTTGACAA
TGAAGAAGTTGGTAGCTCTACTAAACAAGGTGCAGATTCAAACATGTTGTTAAATATATTGGAGAGAATTTGCATATCAA
TGGGTAAGGATAGAGAGGGATTCTTTGAGTCTATTTATTCATCTTTTATGATATCATCAGATTTAGCTCATGCTATTCAT
CCAAACATTCCAGAAAAGCATGACCCAACTAATAAACCAATAATGGGAAAAGGTCCGGTTATAAAGATAAATGCTAGTCA
GGCATATACTAGTGATGGATATTCTATAGCTATTTATAAAAATATATGTAGAGAAGCTAATGTTGAGTATCAAGAATTTG
TTAATAGGTCAGATGAAAGAGGAGGAAGTACTATAGGTCCAATATCTTCTACTCATATAGATATACCATCTGTGGATGTG
GGAAGTCCAATTTTAGCAATGCATTCTATAAGAGAATTAGGAAATGTTGAGGACCACTATAGTATATATAAAACATTTAG
TAAGTTTTTTGAAATATAA

Upstream 100 bases:

>100_bases
ATTGGTACAGATGTTACTATAGCTTTTGACCAACAGGGAATTAAAAAAATAAATAAAGAATATACAACACTAAATATTTT
ATAATGGAGGTAAATGAGGA

Downstream 100 bases:

>100_bases
ATATAAGATAAACAATTTGGAGATGAGACTATGAAATTAGGATTATGTTTAGAAGGTGGAGGAGCAAAAGGGGCTTATCA
AGCAGGAGTAGTTAAAGCCT

Product: aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQRWNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRII
GSHSDSPTFSIKPNAEIEAEKSYLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYEFEKGSLIGANDEFISIGRQDNL
AMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQGADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIH
PNIPEKHDPTNKPIMGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTHIDIPSVDV
GSPILAMHSIRELGNVEDHYSIYKTFSKFFEI

Sequences:

>Translated_432_residues
MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQRWNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRII
GSHSDSPTFSIKPNAEIEAEKSYLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYEFEKGSLIGANDEFISIGRQDNL
AMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQGADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIH
PNIPEKHDPTNKPIMGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTHIDIPSVDV
GSPILAMHSIRELGNVEDHYSIYKTFSKFFEI
>Mature_432_residues
MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQRWNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRII
GSHSDSPTFSIKPNAEIEAEKSYLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYEFEKGSLIGANDEFISIGRQDNL
AMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQGADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIH
PNIPEKHDPTNKPIMGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTHIDIPSVDV
GSPILAMHSIRELGNVEDHYSIYKTFSKFFEI

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=449, Percent_Identity=36.3028953229399, Blast_Score=305, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI17552916, Length=453, Percent_Identity=35.5408388520971, Blast_Score=264, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6321905, Length=464, Percent_Identity=39.0086206896552, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6322746, Length=454, Percent_Identity=27.7533039647577, Blast_Score=197, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 48174; Mature: 48174

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQRWNLRVGGKYYVTKNLS
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEECCEEEEECCHH
AIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKSYLKLNTECYGGAILSTWL
EEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHH
DRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIHLNRSINDGHSYNKQKDMLPL
CCCCCCCCEEEECCCCCCCCCHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHH
VGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYEFEKGSLIGANDEFISIGRQDNL
HHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHEEEEEEECCCCEECCCCCEEEECCCCCE
AMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQGADSNMLLNILERICISMGKDREG
EEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPIMGKGPVIKINASQAYTSDGYSIAIYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEH
NICREANVEYQEFVNRSDERGGSTIGPISSTHIDIPSVDVGSPILAMHSIRELGNVEDHY
HHHHHCCCCHHHHHCCCCCCCCCEECCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHH
SIYKTFSKFFEI
HHHHHHHHHHCC
>Mature Secondary Structure
MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQRWNLRVGGKYYVTKNLS
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEECCEEEEECCHH
AIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKSYLKLNTECYGGAILSTWL
EEEEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCEEECCCEEEECCCCCCCHHHHHHH
DRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIHLNRSINDGHSYNKQKDMLPL
CCCCCCCCEEEECCCCCCCCCHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHH
VGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYEFEKGSLIGANDEFISIGRQDNL
HHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHEEEEEEECCCCEECCCCCEEEECCCCCE
AMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQGADSNMLLNILERICISMGKDREG
EEEEEHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPIMGKGPVIKINASQAYTSDGYSIAIYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEH
NICREANVEYQEFVNRSDERGGSTIGPISSTHIDIPSVDVGSPILAMHSIRELGNVEDHY
HHHHHCCCCHHHHHCCCCCCCCCEECCCCCCEECCCCCCCCCHHHHHHHHHHHCCCHHHH
SIYKTFSKFFEI
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA