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The map label for this gene is groES

Identifier: 126697766

GI number: 126697766

Start: 251943

End: 252227

Strand: Direct

Name: groES

Synonym: CD0193

Alternate gene names: 126697766

Gene position: 251943-252227 (Clockwise)

Preceding gene: 126697765

Following gene: 126697767

Centisome position: 5.87

GC content: 34.04

Gene sequence:

>285_bases
ATGAAAATAAGACCATTAGCTGACAGAGTAGTAATTAAAAAAGTAGAAGCAGAAGAAAAAACTGCAAGTGGAATAGTTTT
ACCAGGAGCAGCTAAAGAGCAACCTCAAATAGCTGAAGTTGTAGAAGTTGGACCAGGTGGAATAGTTGAAGGGAAAGAAA
TAAAAATGGAATTGACAGTGGGAGATAAGGTTATATTCCAAAAATATTCTGGAACAGAAGTTAAGATAGAAGGACAAGAA
TACACAATACTAAGACAGAGTGATGTATTAGCTGTTATTGAATAA

Upstream 100 bases:

>100_bases
AGTATATATATAAATCTACATATATAAGTAGTATTAATTTAAAAATAACTAAAAACATAGGCGAACTAGTCTATACTTAA
TATTTTAGGAGGCGTGAATA

Downstream 100 bases:

>100_bases
ATATAGAATAAATTTATTAGGAGGGGTTTAAAATGGCTAAAGAAATTAAATTTTCAGAGGAAACAAGAAGAGCTTTAGAA
GCTGGTGTAAATAAATTAGC

Product: 10 kDa chaperonin

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQE
YTILRQSDVLAVIE

Sequences:

>Translated_94_residues
MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQE
YTILRQSDVLAVIE
>Mature_94_residues
MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQE
YTILRQSDVLAVIE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=45.8333333333333, Blast_Score=79, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=42.5531914893617, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=38.7096774193548, Blast_Score=62, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CLOD6 (Q18CT6)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001086663.1
- ProteinModelPortal:   Q18CT6
- SMR:   Q18CT6
- STRING:   Q18CT6
- GeneID:   4915462
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0193
- NMPDR:   fig|1496.1.peg.1470
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   RIVIQQV
- ProtClustDB:   CLSK2534417
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10220; Mature: 10220

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTV
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEE
GDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVGPGGIVEGKEIKMELTV
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEE
GDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA