Click here to switch to the map view.

The map label for this gene is secA1

Identifier: 126697715

GI number: 126697715

Start: 189276

End: 191951

Strand: Direct

Name: secA1

Synonym: CD0143

Alternate gene names: 126697715

Gene position: 189276-191951 (Clockwise)

Preceding gene: 126697714

Following gene: 126697716

Centisome position: 4.41

GC content: 32.25

Gene sequence:

>2676_bases
ATGAGCTTTATGGATAATTTATTCAACATGGCAGATAAAAAAGAATTAAAAAAGTTCAATAAAACTGTTGATATAATAGA
TTCATTAGAACCTAAATTTGAATCTATGGCAGACTCGGAACTTAAAAATATGACAAATATATTTAAAGAAAGATTAGCAA
ATGGTGAAAGTATAGATGATATACTTCCAGAAGCTTTTGCAGTAGTTAGAGAAGTTTCTAAGAGAGTGTTAGGACTTAGA
CACTACAGAGTTCAAATGATTGGAGGTATAGTACTACATCAAGGAAGAATAGCAGAAATGAAAACAGGTGAAGGTAAAAC
TTTGGTTGCAACTGCTCCTGTTTATTTGAATGCGCTTACTGGAAAAGGTGTACATGTTGTAACAGTAAATGATTACCTTG
CAAAACGTGATAGAGACCAAATGGCAAAAATCTATGAGTTTTTAGGAATGAGTGTAGGCGTTATTATACACGGTCAAAAT
CCAAAAGTTAGAAAAGAACAATATGATTGTGATATAACTTATGGTACAAATAATGAATATGGATTTGACTATCTAAAGGA
CAATATGGTAATACACAAAGAGCAAAGAGTTCAAAGAGGATTAAATTATGCTATAGTGGATGAGGTTGACTCTATACTAA
TAGATGAGGCTAGAACACCACTTATCATATCTGGACCTGGAGACAAATCAACTCACTTATATTCAGATGCAAACACATTT
GTTTTAACCTTAAAACCAGATGATTATGAATTAGAAGAAAAAGATAAGGCTGTATCTCTAACAGCATCGGGTATACAAAA
AGCAGAAGTGTATTTTAATGTTGATAATATAACAGATATATCTCATACAGAATTATACCATCATATAAATCAAGCTTTAA
GAGCACATGTAATAATGAAGAAAGATGTTGATTATGTTGCTAAAGATGGAGAAATAGTAATAGTAGATGAGTTCACAGGT
AGACTTATGTTTGGTAGAAGATATTCAGAAGGTTTACATCAAGCAATAGAGGCTAAAGAAGGTCTTAAAATACAAAGAGA
ATCTAAAACACTAGCTACTGTAACATTCCAAAACTACTTTAGAATGTACAAAAAACTTTCTGGTATGACTGGTACAGCAA
AAACAGAAGAAGAAGAGTTTAAAGCAATCTACAAAATGGATGTTTTCCAAGTACCTACTAATAAGCTTATGATAAGGGAA
GACTTACCAGACTGTGTATACAAAAGTGAAATAGGTAAATTTAATGCTGTAGCACAAGAAATAATTGAAAGGCACAAAGT
CAATCAACCAATACTTGTAGGTACAGTATCAATAGAAAAATCAGAATTATTATCACAAATACTAAAGAAAAAGGGCATAA
AGCACGAGGTATTAAATGCTAAGCATCATGATAAAGAGGCAGAAATAATAGCACAAGCTGGTAGACTTGGAGCTGTTACA
ATAGCTACTAATATGGCTGGTCGTGGTACAGATATAGTTCTAGGTGGAAATCCAGATTTTTTAACTAAGAGAGAAATGAG
AAGAAATGGATTTAAAGAAGAAATAGTAAATAGAGTAGATACTCCAATAGAAGGTATACCTGTAAAAGGTAATGAAATTC
TATTTGAAGCTAGAGAAGAGTATGAAAAACTATTTGAAAAGTTTAAGCAACAAACGCAAGAAGAACAAAAACAAGTTGTA
GAAGCAGGTGGACTTGCTATAATCGGTACAGAAAGACACGAATCTCGAAGAATAGATAACCAGTTGAGAGGTCGTGCTGG
ACGTCAAGGTGACCCAGGGAGTTCAAGATTCTATATAGGTCTTGATGATGACCTTATGAGATTGTTTGGTAGTGATAGAA
TATCTGGTATTGTAGATAAAATAGGTCTTGAAGAAGACATGCCGATAGAACATAGAATATTATCTAAGTCTATTGAAGGA
GCACAAAAGAAAGTCGAAGGTAAAAACTTTGGAATAAGAAAGCATGTACTTCAATATGATGATGTTATGAATAAACAAAG
AGAAATAATATATGCAGAGAGAAAACGTGTATTAGAAGGTGAAGATTTACAAGAACAAATACAATCAATGACTCATTCTA
TAATAGAAGAAGCAGTTACTCTTTATACACAAGATAAAGGATTTGATGAAGAAGGATTCAAAGAACATATGTATAATCTG
TTCTTGCCAAAAGGTAGCATAGAAATACCAGAAATAGAAAAACTTAATCCAGTTGAAATAACAGAAAAAGTTTATGAAAT
AGCTATGAAGATATATACTTCAAAAGAAGAACAAGTTGGCTATGAGAGAATGAGAGAAGTTGAGAGAGTAATCTTACTTC
AAGCTGTTGATAACCATTGGATAGACCATATAGATGCTATGGACCAATTACGCCAAGGTATTGGTCTTCGTGCTGTAGGT
CAGCAAGACCCAGTTATTGCTTATAAAATGGAAGGTTTTGATATGTTTGATGAAATGAATAAACATATCAAAGAAGATAC
TGTAAGATATTTATTTAATATAACAATAGAAACTCCAGTGGAAAGAAAAGCAGTTGTAGATGTTGAAAATCTATCTTCTC
CATCAGATGGAACACTTCCAACAAGTAAAACTGTTAAAAAAGATGAAAAGGTTGGAAGAAATGACTTATGCCCTTGTGGA
AGTGGTAAAAAATATAAAAACTGTTGTGGAAGATAA

Upstream 100 bases:

>100_bases
ATAAATAAATTATCGATAGCTTTTTAAATTAATATTAAAAGTATAGTTTTTATGGTAAAATGAATAATAGTACAATAAAG
AACGAGGAGAGATGTAAAAT

Downstream 100 bases:

>100_bases
TCTCGGAGGATTAAATGTTAAAGTTACAAGAGTATAAACATAGTATGGAGCAGATGGCTTCAAATTTAGAAGAATTGAGG
GTTTCTCTTTGACATAGCTT

Product: preprotein translocase SecA subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDDILPEAFAVVREVSKRVLGLR
HYRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTF
VLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTG
RLMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIRE
DLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVT
IATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVV
EAGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEG
AQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNL
FLPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRAVG
QQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCG
SGKKYKNCCGR

Sequences:

>Translated_891_residues
MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDDILPEAFAVVREVSKRVLGLR
HYRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTF
VLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTG
RLMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIRE
DLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVT
IATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVV
EAGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEG
AQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNL
FLPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRAVG
QQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCG
SGKKYKNCCGR
>Mature_890_residues
SFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRH
YRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQNP
KVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTFV
LTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGR
LMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIRED
LPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVTI
ATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVE
AGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEGA
QKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLF
LPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRAVGQ
QDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCGS
GKKYKNCCGR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=930, Percent_Identity=47.9569892473118, Blast_Score=847, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_CLOD6 (Q18CN0)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001086612.1
- ProteinModelPortal:   Q18CN0
- SMR:   Q18CN0
- STRING:   Q18CN0
- GeneID:   4914134
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0143
- NMPDR:   fig|1496.1.peg.1523
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   VEVEREN
- ProtClustDB:   CLSK2534398
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 101566; Mature: 101435

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCEEEEEEC
GKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQNPKVRKEQYDCDITYGTNNEY
CCCEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEECCCCCC
GFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTF
CCHHHHCCEEEEHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCEE
VLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMK
EEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYF
CCCHHHCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHH
RMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIREDLPDCVYKSEIGKFNAVAQE
HHHHHHCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHCCHHHHHHHH
IIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVT
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCCCEEEE
IATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREE
EEECCCCCCCEEEECCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
YEKLFEKFKQQTQEEQKQVVEAGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIG
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
LDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYD
CCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDHIDAMDQLRQGIGLRAVGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPV
HHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEEEEECCC
ERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR
CCHHEEEHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
SFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEECCEEEEEEC
GKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQNPKVRKEQYDCDITYGTNNEY
CCCEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCEEEEECCCCCC
GFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTF
CCHHHHCCEEEEHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCEE
VLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMK
EEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYF
CCCHHHCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHHHCCCEEEECCCEEEEHHHHHHH
RMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIREDLPDCVYKSEIGKFNAVAQE
HHHHHHCCCCCCCCCCHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHCCHHHHHHHH
IIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVT
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCCCEEEE
IATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREE
EEECCCCCCCEEEECCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
YEKLFEKFKQQTQEEQKQVVEAGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIG
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
LDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYD
CCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
DVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
FLPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IDHIDAMDQLRQGIGLRAVGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPV
HHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHEEEEEEEEECCC
ERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR
CCHHEEEHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA