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The map label for this gene is murA [H]

Identifier: 126697695

GI number: 126697695

Start: 168164

End: 169435

Strand: Direct

Name: murA [H]

Synonym: CD0123

Alternate gene names: 126697695

Gene position: 168164-169435 (Clockwise)

Preceding gene: 126697694

Following gene: 126697696

Centisome position: 3.92

GC content: 33.88

Gene sequence:

>1272_bases
ATGAGGAGATCAAAAAATATGGCTAAGATAATAGTAAAAAAGAGTAATCCACTTAAAGGTAGTGTTAAAATAGATGGTGC
AAAAAATGCAGTTTTACCAATAATAGCAGCGACTTTATTAGCAAACGGAAAATCAACATTAAATGGAGTACCAAATTTAA
GAGATGTTCATGTTATATCAGATTTATTAAGACATGTAGGAGCAGAAGTTGAATATAAAGAAAATACACTTACTGTTGAT
GCAAGCAATATAAAAACTTGTGAAGCTCCATATGAGCTTGTAAGAAAGATGAGAGCTTCTTTTTTGGTTATGGGACCATT
GCTTGCTAGATTTAATAGTACGAAAATTTCTATGCCAGGAGGATGTGCTATAGGAACAAGACCTATAGATTTACATTTAA
AAGGATTTAAAGCTTTAGGTGCAAAGATAGAAATGGACCATGGTTTTGTTGAAGCAGCAACAGAAAAGTTAGTAGGAAAT
AAATTATATTTAGATTTCCCATCTGTTGGAGCAACTGAAAACATAATGATGGCAGCTTCTTTAGCAGAAGGGACTACAAT
AATAGAGAATGCAGCAGAAGAGCCAGAAATAGTAGATTTAGCAAACTTCTTGAACGAAATGGGAGCAGATGTTAAAGGTG
CAGGTACTAATACTATAAAAATAAAAGGTGTTAAAGAGTTAAAAGGAGCAGAACATAATGTAATTCCAGACAGAATAGAA
GCAGCAACTTATATGGTTGCAGCAGCTATGACAAAAGGTGATATAACTGTTGAAAATGTTTTAATGGAGCATTTAAAACC
AGTTGTAGCTAAATTAAGAGAAGCTGGTTGTGAAATAACAGAAATGGACAATTCTGTAAGAGTTGTAGGTCCAAAAGTAT
TAAAACCAATAGATATAAAAACTTTACCACATCCAGGATTTCCTACAGATGTTCAAGCACAATTTATGGCTATGCTTACT
GTAGCCAATGGAACTGGTGTAGTTATAGAAACTGTTTTTGAAAACAGATTTATGCATGTTGCTGAATTTAATAGAATGGG
TGCTAATATAAAAATAGATGGAAGAAGTGCGGTTGTTAATGGTGTAGATGAGCTACACGGTGCAGCAGTAAACGCTACTG
ATTTAAGAGCAGGGGCAGCCCTTATTTTATGCGGTCTTATAGCAGAAGGAGAAACTCAAATAGGAGAAATATACCATATC
CAAAGAGGTTATGTTGATATAGATAAGAAGATAACAGCTCTAGGTGGTCAAATCGAAATAGTAGAAGATTAA

Upstream 100 bases:

>100_bases
GGGAAAAAATTAATTTAAATATAGGAATTAAATATAATGAGGATGACGGAAAAACACTCATATATATTGCCACACCAATT
ATAAAATTAGATTATTAATT

Downstream 100 bases:

>100_bases
TAATTGGTTTATAGAAGAAAGTTATAAATTAATAGGGTTGTTCATATACTTAAATACAAGGTTTTAAAAGCTAAGGAGGA
GAGTATATGAAGAACCCATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRRSKNMAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGVPNLRDVHVISDLLRHVGAEVEYKENTLTVD
ASNIKTCEAPYELVRKMRASFLVMGPLLARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGN
KLYLDFPSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGVKELKGAEHNVIPDRIE
AATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEMDNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLT
VANGTGVVIETVFENRFMHVAEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIYHI
QRGYVDIDKKITALGGQIEIVED

Sequences:

>Translated_423_residues
MRRSKNMAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGVPNLRDVHVISDLLRHVGAEVEYKENTLTVD
ASNIKTCEAPYELVRKMRASFLVMGPLLARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGN
KLYLDFPSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGVKELKGAEHNVIPDRIE
AATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEMDNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLT
VANGTGVVIETVFENRFMHVAEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIYHI
QRGYVDIDKKITALGGQIEIVED
>Mature_423_residues
MRRSKNMAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGVPNLRDVHVISDLLRHVGAEVEYKENTLTVD
ASNIKTCEAPYELVRKMRASFLVMGPLLARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGN
KLYLDFPSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGVKELKGAEHNVIPDRIE
AATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEMDNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLT
VANGTGVVIETVFENRFMHVAEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIYHI
QRGYVDIDKKITALGGQIEIVED

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=49.5215311004785, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45368; Mature: 45368

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSKNMAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGVPNLRDVHVIS
CCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHH
DLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLLARFNSTKISMPG
HHHHHCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDFPSVGATENIMMAAS
CCEECCCEEEEEEECHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEH
LAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGVKELKGAEHNVIPDRIE
HCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCHHHH
AATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEMDNSVRVVGPKVLKPIDIK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCCCCE
TLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHVAEFNRMGANIKIDGRSAVVN
ECCCCCCCCCHHHHEEEEEEEECCCCEEEEEEHHCCCEEHHHHHHCCCEEEECCCHHHHC
GVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIYHIQRGYVDIDKKITALGGQIEI
CHHHHCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCEECCCEEEE
VED
ECC
>Mature Secondary Structure
MRRSKNMAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGVPNLRDVHVIS
CCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHH
DLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLLARFNSTKISMPG
HHHHHCCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
GCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDFPSVGATENIMMAAS
CCEECCCEEEEEEECHHHCCCEEEECCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEH
LAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGVKELKGAEHNVIPDRIE
HCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHCCCCCCCCCHHHH
AATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEMDNSVRVVGPKVLKPIDIK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCCCCE
TLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHVAEFNRMGANIKIDGRSAVVN
ECCCCCCCCCHHHHEEEEEEEECCCCEEEEEEHHCCCEEHHHHHHCCCEEEECCCHHHHC
GVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIYHIQRGYVDIDKKITALGGQIEI
CHHHHCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCEECCCEEEE
VED
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]