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The map label for this gene is vorA [H]

Identifier: 126697690

GI number: 126697690

Start: 161043

End: 161600

Strand: Direct

Name: vorA [H]

Synonym: CD0118

Alternate gene names: 126697690

Gene position: 161043-161600 (Clockwise)

Preceding gene: 126697689

Following gene: 126697691

Centisome position: 3.75

GC content: 34.05

Gene sequence:

>558_bases
ATGTCTACAGCTAGAGTAATATGTGCAGGCTTCGGAGGCCAAGGTGTTATGTCTATGGGGCAATTACTTACTTATGCAGG
AATGCTAGAAGGAAAAGAAGTTTCTTGGTTACCATCTTATGGACCAGAAATGCGTGGAGGTACAGCAAACTGTGCAGTAA
CTGTATCTAATGAGCCAGTTGGTTCTCCACTTATAACAGATGATGCAACTGCAGCTATATTATTAAATATACCAGCATTT
GAAAAATTCAAAGATGATGTTATTCCTGGTGGAAAAATAATAGTAAATAGTTCTTTAATAAAAGAAAAAGTTGATAGAAC
AGATGTAGATGTTTATTATATACCAGCAAATGAATTAGCAGCTGAATTAGGAAATGATAAAGTTGCTAACATGATAATGT
TAGGCGCTTACTTAAAAGTATCTGATACTGTAGATATAGAATCTGTACTAGAAGCATTCAAAAAAGTTTTCGGACCTAGA
AAAGAAAAATTCGTTCCATTAAACAGAGAAGCTTTACAAAAAGGTATGGATGCTACATGTTCTAAAGCAACTAACTAA

Upstream 100 bases:

>100_bases
ACTAGCTCCAAACGATGCTTTACAATGGTTAAGAGACAACATGATACCATACTATCCATTAGGAAATTTCAAAAATGTTG
AAGTTGAGGAGGTGAAGTAA

Downstream 100 bases:

>100_bases
TAAAGAAAAAGATGTCAAAAAAAAGACAATAGAATTATTTCTATTGTCTTTTTTGCTGATAAGTATTAAAATATTTTTAT
GACTGAAATTAAGCCTATAA

Product: subunit of oxidoreductase

Products: succinyl-CoA; CO2; reduced ferredoxin

Alternate protein names: VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAF
EKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
KEKFVPLNREALQKGMDATCSKATN

Sequences:

>Translated_185_residues
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAF
EKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
KEKFVPLNREALQKGMDATCSKATN
>Mature_184_residues
STARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFE
KFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRK
EKFVPLNREALQKGMDATCSKATN

Specific function: Unknown

COG id: COG1014

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019752
- InterPro:   IPR002869
- InterPro:   IPR011766 [H]

Pfam domain/function: PF01558 POR; PF02775 TPP_enzyme_C [H]

EC number: 1.2.7.3

Molecular weight: Translated: 19784; Mature: 19653

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPV
CCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCC
GSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELA
CCCEECCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHHHCCCCCEEEEECHHHHH
AELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRKEKFVPLNREALQKGMDATC
HHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCH
SKATN
HCCCC
>Mature Secondary Structure 
STARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEMRGGTANCAVTVSNEPV
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEECCCCC
GSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKEKVDRTDVDVYYIPANELA
CCCEECCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHHHCCCCCEEEEECHHHHH
AELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPRKEKFVPLNREALQKGMDATC
HHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCH
SKATN
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-oxoglutarate; CoA; oxidized ferredoxin

Specific reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9108258 [H]